Clinical trials

Introduction Current clinical practice struggles to measure elbow joint movements effectively. This study introduces a new device called the Elbow Joint Torque Measurement Device (EJTMD) that measures muscle strength and range of motion in a more accurate way. Study Overview In this study, 22 healthy individuals and 22 stroke patients participated in a randomized trial. […] ➡️➡️➡️

Background Antibiotics are often used in Neonatal Intensive Care Units (NICUs) for babies suspected of having infections. The decision to stop these antibiotics usually depends on the baby’s health and the results of blood tests. Sometimes, delays in getting these test results can lead to longer antibiotic use. Objective We wanted to see if having […] ➡️➡️➡️

“`html Study Overview This study focused on how Total Motion Release (TMR) and caffeine can improve key performance areas for male sprinters, including physical ability and mental performance. Research Design A total of 56 male sprinters participated in this trial. They were divided into four groups: a control group, a caffeine group, a TMR group, […] ➡️➡️➡️

Study Overview This study looked at how early use of indirect calorimetry (IC) can help critically ill patients with acute kidney injury (AKI) by guiding their nutrition. The aim was to see if this approach could improve survival rates and kidney health. Study Details We conducted a trial with patients in the Intensive Care Unit […] ➡️➡️➡️

Background Bowel cancer is a leading cause of cancer deaths, but early diagnosis can significantly improve survival rates. Unfortunately, individuals with mental health issues like anxiety and depression (A/D) often struggle to engage in important health behaviors that can lead to early detection. Aims This study aimed to investigate three key areas related to early […] ➡️➡️➡️

Understanding Cognitive Changes in Multiple Sclerosis Cognitive impairment is a common issue for people with multiple sclerosis (MS). To improve clinical trials, we need to accurately measure changes in cognitive abilities. Study Overview This study focused on a phase-3 trial of a drug called natalizumab for patients with secondary progressive MS (SPMS). The trial included […] ➡️➡️➡️

“`html Nutrients Study Overview This study investigates how pomegranate extract (PE) can help reduce inflammation and improve heart health in older adults. Study Details In this trial, 86 participants aged 55-70 were divided into two groups: one received daily doses of pomegranate extract (740 mg), while the other received a placebo for 12 weeks. Measurements […] ➡️➡️➡️

Background Patients with head and neck cancer often face serious oral health issues during chemotherapy and radiation therapy. These problems can include painful sores in the mouth, infections, difficulty speaking and eating, bleeding gums, and stiff tissue. Study Overview This study aimed to see how effective a specific oral care plan (OCIP) was in improving […] ➡️➡️➡️

Cardiac Impact of Tadalafil in Duchenne Muscular Dystrophy Background: Tadalafil, a medication that inhibits phosphodiesterase 5 (PDE5), was tested to see if it could slow the progression of Duchenne muscular dystrophy (DMD). A major study found that it did not prevent loss of walking ability, but we will discuss its effects on heart health. Study […] ➡️➡️➡️

Overview of the Study This study focuses on how young people often feel anxious in social situations due to fear of being judged. It explores short digital tools designed to help manage this anxiety, particularly during situations where they feel evaluated by others. Study Details One hundred twenty healthy young individuals participated in the study. […] ➡️➡️➡️

Reducing Radiation in Lung Tumor Treatment It’s crucial to lower radiation exposure while ensuring effective treatment for lung tumors. This study explores a new technology called spectral shaping to achieve this during microwave ablation (MWA). Study Overview We conducted a clinical trial with 114 patients diagnosed with lung cancer, who were set to undergo CT-guided […] ➡️➡️➡️

Background When patients have acute cholecystitis, the timing of surgery can vary. Some patients have surgery early (within 7 days), while others may have it later (after 7 days). Early surgery might lead to better health outcomes because it reduces the time patients are exposed to complications. This study aimed to see if it is […] ➡️➡️➡️

Atrial Fibrillation and Stroke Prevention Background Atrial fibrillation (AF) increases the risk of stroke. Anticoagulation medications (OAC) help prevent strokes but may also cause bleeding. Current guidelines don’t clearly suggest whether patients with borderline stroke risk should use OAC. Understanding the risks and benefits can help patients make better decisions. Study Objective This study aimed […] ➡️➡️➡️

Summary of Research on Irritability in Depressed Adolescents This study examined how irritability affects treatment outcomes in adolescents with major depressive disorder (MDD) using transcranial magnetic stimulation (TMS). Key Findings Irritability, a common problem for many adolescents, improved significantly during TMS treatment: Irritability decreased for both 1 Hz and 10 Hz TMS groups. Irritability improvements […] ➡️➡️➡️

Introduction to Laser Patterned Microcoagulation (LPM) Laser patterned microcoagulation (LPM) is a new treatment option for desquamative gingivitis caused by oral lichen planus (OLP). This clinical trial tested how effective LPM is in reducing symptoms compared to a control treatment. Study Overview The study was conducted with 30 patients who had OLP presenting as desquamative […] ➡️➡️➡️

Clinical Trial Summary: LY05008 vs. Dulaglutide Background Dulaglutide is a medication for type 2 diabetes that helps control blood sugar and lower heart disease risks. A new drug, LY05008, was tested to see if it works similarly to dulaglutide. Study Design In this study, 440 Chinese adults with type 2 diabetes were randomly assigned to […] ➡️➡️➡️

Clinical Trial Overview This study looked at whether adding psychomotor therapy could help improve treatment outcomes for young adults who stutter. Study Details A total of 47 young adults, with an average age of 24 years, were involved in the trial. They were divided into two groups: Control Group: 24 participants received standard treatment for […] ➡️➡️➡️

Study Overview This study aimed to compare two types of dental splints for patients with a specific jaw issue called anterior disc displacement with reduction (DDWR). The two splints tested were: Anterior Repositioning Splint (ARS) Stabilization Splint (SS) Study Design The study involved 20 patients diagnosed with anterior disc displacement. They were randomly divided into […] ➡️➡️➡️

Study Overview This study focuses on a treatment for sudden sensorineural hearing loss using a special form of medication called methylprednisolone acetate nanogel. It was conducted in a hospital in Iran with 96 patients participating. Treatment Groups Patients were divided into two groups: Intervention Group: 40 patients received intratympanic injections of methylprednisolone acetate nanogel four […] ➡️➡️➡️

Study Overview This study looked at how effective a method called selective removal of carious tissue (SRCT) is for treating cavities in permanent teeth. Methods Used The researchers conducted a clinical trial with 74 teeth. They compared SRCT with two other methods of removing cavities: Non-selective removal to hard dentin (nSRCT-HD) for medium-depth cavities. Stepwise […] ➡️➡️➡️