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Clinical study on the treatment of Qingfei Paidu Granules combined with nondrug therapy for asymptomatic patients with novel coronavirus
Summary of Clinical Study on Qingfei Paidu Granules and Nonpharmacological Interventions for Asymptomatic COVID-19 Patients Background The study evaluated the effectiveness of Qingfei Paidu Granules (QFPG) and nonpharmacological interventions in managing asymptomatic novel coronavirus infection, acknowledging the significant role of Traditional Chinese Medicine (TCM) in pandemic intervention. Methods Asymptomatic individuals were randomly assigned to three…
Adverse effects, Clinical outcomes, Clinical research, Clinical study, Control arm, Data collection, Double-blind, Drug trial, Efficacy, Patient consent, Patient enrollment, Placebo, Randomization, Regulatory approval, Safety profile, Study design, Study protocol, Treatment group, Trial monitoring, Trial phase -
Comparison of the pleiotropic effect of atorvastatin and rosuvastatin on postmenopausal changes in bone turnover: A randomized comparative study
Comparison of Atorvastatin and Rosuvastatin Effects on Bone Turnover in Postmenopausal Women Key Findings: • Statins, commonly used for dyslipidemia, may have additional benefits on bone health. • This study compared the impact of atorvastatin and rosuvastatin on bone turnover in postmenopausal women. • After 12 months, atorvastatin showed potential superiority in inhibiting adverse changes…
Adverse effects, Clinical outcomes, Clinical research, Clinical study, Control arm, Data collection, Double-blind, Drug trial, Efficacy, Patient consent, Patient enrollment, Placebo, Randomization, Regulatory approval, Safety profile, Study design, Study protocol, Treatment group, Trial monitoring, Trial phase -
Neuromuscular electrical stimulation for physical function maintenance during hematopoietic stem cell transplantation: Study protocol
Neuromuscular Electrical Stimulation for Physical Function Maintenance during Hematopoietic Stem Cell Transplantation: Study Protocol Overview Hematopoietic stem cell transplantation (HCT) is a common treatment for blood cancers but can lead to long-term functional impairment, fatigue, and decreased quality of life. Traditional exercise is not consistently recommended or maintained by patients. This study aims to assess…
Adverse effects, Clinical outcomes, Clinical research, Clinical study, Control arm, Data collection, Double-blind, Drug trial, Efficacy, Patient consent, Patient enrollment, Placebo, Randomization, Regulatory approval, Safety profile, Study design, Study protocol, Treatment group, Trial monitoring, Trial phase -
A Digital Cognitive-Physical Intervention for Attention-Deficit/Hyperactivity Disorder: Randomized Controlled Trial
Study Title: A Digital Cognitive-Physical Intervention for Attention-Deficit/Hyperactivity Disorder: Randomized Controlled Trial Background ADHD is a common neurodevelopmental disorder in children. This study aimed to assess the effectiveness of BrainFit, a digital intervention combining cognitive and exercise training, in reducing ADHD symptoms and improving executive function in school-aged children. Methods The study included 90 children…
Adverse effects, Clinical outcomes, Clinical research, Clinical study, Control arm, Data collection, Double-blind, Drug trial, Efficacy, Patient consent, Patient enrollment, Placebo, Randomization, Regulatory approval, Safety profile, Study design, Study protocol, Treatment group, Trial monitoring, Trial phase -
Long-Term Effect of Home Blood Pressure Self-Monitoring Plus Medication Self-Titration for Patients With Hypertension: A Secondary Analysis of the ADAMPA Randomized Clinical Trial
Long-Term Effect of Home Blood Pressure Self-Monitoring Plus Medication Self-Titration for Patients With Hypertension: A Secondary Analysis of the ADAMPA Randomized Clinical Trial Summary: BP self-monitoring and self-titration of antihypertensive medication, in combination with primary-care nursing involvement, were found to effectively lower blood pressure in the longer term without increasing health care use or adverse…
Adverse effects, Clinical outcomes, Clinical research, Clinical study, Control arm, Data collection, Double-blind, Drug trial, Efficacy, Patient consent, Patient enrollment, Placebo, Randomization, Regulatory approval, Safety profile, Study design, Study protocol, Treatment group, Trial monitoring, Trial phase -
Comparison of local massage, steroid injection, and extracorporeal shock wave therapy efficacy in the treatment of lateral epicondylitis
Comparison of Treatments for Lateral Epicondylitis Study Overview This study compared the effectiveness of local massage, corticosteroid injection, and extracorporeal shock wave therapy (ESWT) in treating lateral epicondylitis (LE). Key Findings ESWT showed superior results compared to the other treatments, with significant improvements in clinical evaluation scores at the six-month follow-up. Practical Solutions and Value…
Adverse effects, Clinical outcomes, Clinical research, Clinical study, Control arm, Data collection, Double-blind, Drug trial, Efficacy, Patient consent, Patient enrollment, Placebo, Randomization, Regulatory approval, Safety profile, Study design, Study protocol, Treatment group, Trial monitoring, Trial phase -
Paraxanthine provides greater improvement in cognitive function than caffeine after performing a 10-km run
Paraxanthine Improves Cognitive Function After Exercise Study Details Researchers investigated the effects of paraxanthine (PX) and caffeine (CA) on cognitive function after exercise. PX, a caffeine metabolite, was found to enhance cognitive performance without the limitations of caffeine habituation and genetic sensitivity. Method 12 trained runners were given different treatments in a double-blind, randomized, crossover…
Adverse effects, Clinical outcomes, Clinical research, Clinical study, Control arm, Data collection, Double-blind, Drug trial, Efficacy, Patient consent, Patient enrollment, Placebo, Randomization, Regulatory approval, Safety profile, Study design, Study protocol, Treatment group, Trial monitoring, Trial phase -
Cost-effectiveness and cost-benefit analyses of fluoride varnish for caries prevention in Guangxi, China
Cost-effectiveness and Cost-benefit of Fluoride Varnish for Caries Prevention Summary This study evaluated the cost-effectiveness and cost-benefit of fluoride varnish (FV) interventions for preventing caries in the first permanent molars (FPMs) among children in rural areas in Guangxi, China. The findings suggest that a comprehensive intervention combining FV application with oral health education is more…
Adverse effects, Clinical outcomes, Clinical research, Clinical study, Control arm, Data collection, Double-blind, Drug trial, Efficacy, Patient consent, Patient enrollment, Placebo, Randomization, Regulatory approval, Safety profile, Study design, Study protocol, Treatment group, Trial monitoring, Trial phase -
ØCD: protocol for the development and evaluation of a cognitive-behavioral prevention program for obsessive-compulsive disorder
Study Overview OCD imposes significant burdens and has been exacerbated by the COVID-19 pandemic. This study aims to develop and validate a prevention program for at-risk adults utilizing cognitive-behavioral therapy and exposure response prevention techniques. Methods The study will involve a single-blind, randomized controlled trial comparing the prevention program to a waitlist control group. At-risk…
Adverse effects, Clinical outcomes, Clinical research, Clinical study, Control arm, Data collection, Double-blind, Drug trial, Efficacy, Patient consent, Patient enrollment, Placebo, Randomization, Regulatory approval, Safety profile, Study design, Study protocol, Treatment group, Trial monitoring, Trial phase -
Randomized comparison of the effects of tailored text messaging versus pillbox organizers on medication adherence of heart failure patients
Comparing Text Messaging and Pillbox Organizers for Heart Failure Medication Adherence Background Heart failure affects millions and non-adherence to medication is a common problem. New reminders like text messaging show promise in improving adherence. Methods 189 heart failure patients were randomly assigned to tailored text messaging (TTM), pillbox organizers, or control. Medication adherence was measured…
Adverse effects, Clinical outcomes, Clinical research, Clinical study, Control arm, Data collection, Double-blind, Drug trial, Efficacy, Patient consent, Patient enrollment, Placebo, Randomization, Regulatory approval, Safety profile, Study design, Study protocol, Treatment group, Trial monitoring, Trial phase