Clinical Trials

Background The need for therapy is growing, but there aren’t enough therapists available. This study looks at how an AI chatbot named Friend can help people during tough times, especially compared to regular therapy. Methods We conducted a study with 104 women who have anxiety and live in war zones. They were split into two […] ➡️➡️➡️

Understanding PFKFB3 and Its Role in Breast Cancer Treatment Background Research shows that higher levels of a protein called PFKFB3 can be found in several types of cancer. This protein helps cancer cells to survive radiation therapy. The SweBCG91RT trial looked at whether measuring PFKFB3 could help predict how well breast cancer patients respond to […] ➡️➡️➡️

Background The study focused on a drug called asciminib for patients with chronic myeloid leukemia (CML) in the chronic phase. The goal was to improve how we understand the drug’s effects in different patient groups and ensure it works effectively and safely. Methods Researchers used data from various studies involving patients with different stages of […] ➡️➡️➡️

Background Music can help reduce anxiety for patients before surgery. However, we didn’t know how long the music should be played to be effective. This study aimed to find out how long different types of music need to be played to help calm pregnant women waiting for cesarean delivery. Methodology We conducted a study where […] ➡️➡️➡️

Study Overview This study looked at the effects of arimoclomol on muscle health in people with inclusion body myositis (IBM) using advanced imaging techniques called quantitative magnetic resonance imaging (qMRI). The goal was to see if qMRI could be a useful tool in tracking treatment outcomes. Study Design Eighteen participants were involved in this study, […] ➡️➡️➡️

Background There is a strong need to help patients with inherited cancer risks and their family members. Engaging these patients can help their families understand genetic risks better. The Genetic Information and Family Testing (GIFT) Study aims to support patients with inherited cancer risks and assist their relatives in starting genetic risk evaluations, including home […] ➡️➡️➡️

Study Overview This study focused on how peer group management can help people with chronic pain, especially those who struggle to work due to their condition. It explored whether group support could provide relief when traditional treatments fall short. Who Participated? The participants were employees aged 18-65 from the Municipality of Helsinki, mostly women (83%). […] ➡️➡️➡️

Background Postural orthostatic tachycardia syndrome (POTS) causes symptoms like dizziness and rapid heartbeat when standing up. It is often seen in people recovering from COVID-19. Study Purpose This study aimed to test if low-level tragus stimulation (LL-TS) could help patients with POTS after COVID-19. Study Details We included 57 participants who had POTS after COVID-19. […] ➡️➡️➡️

Importance of Cognitive Behavioral Therapy for Insomnia (CBT-I) CBT-I can help reduce symptoms of depression, but we need to understand how it works better. Study Objective The goal of this study was to see if CBT-I changes the way people perceive emotions in facial expressions and if these changes help improve depressive symptoms. Study Design […] ➡️➡️➡️

Introduction Patients in COVID-19 intensive care units often face psychological challenges like anxiety and depression. These issues can hinder their recovery. This study looks at how a supportive training program can help reduce these symptoms in hospitalized patients. Study Overview In 2021, a study was conducted with 60 COVID-19 patients in Najaf hospitals. Patients were […] ➡️➡️➡️

Background Breast cancer is the most common cancer among women globally, with triple-negative breast cancer (TNBC) being the most aggressive type. In India, TNBC makes up about one-third of all breast cancer cases. While adding pembrolizumab to standard chemotherapy has shown benefits, many patients in low- and middle-income countries cannot access this treatment due to […] ➡️➡️➡️

Research Findings on Trigger Warnings A recent study examined the effectiveness of trigger warnings for emotionally challenging content. It found that both traditional and modified trigger warnings do not significantly reduce distress in individuals, including those who may be more vulnerable due to anxiety or trauma. Study Overview The study involved 606 university students who […] ➡️➡️➡️

Introduction Oligodendroglioma (ODG) is a rare brain tumor that mostly affects younger adults. Treatment usually involves surgery, radiation therapy (RT), and chemotherapy. However, traditional RT can lead to long-term problems with thinking and quality of life. Proton beam therapy (PBT) may offer a better option by reducing radiation exposure to healthy brain tissue. Study Overview […] ➡️➡️➡️

Study Overview This study looked at the effects of aspirin and omega-3 fatty acids (FAs) on age-related macular degeneration (AMD), a major eye condition affecting older adults. It was part of a larger trial aimed at understanding heart health in people with diabetes. Research Purpose The goal was to determine if aspirin and omega-3 FAs […] ➡️➡️➡️

Background There are not many approved treatments for aggression and agitation in dementia patients. Although antipsychotics and benzodiazepines are often used, they can have serious side effects. Weighted blankets may offer a non-drug option to help reduce agitation in these patients. Objective This study aims to explore how weighted blankets affect aggression and agitation in […] ➡️➡️➡️

Background Acute kidney injury (AKI) can lead to serious health problems and high medical costs. An electronic alert system was created to help doctors diagnose AKI more effectively by automatically collecting important information and sending alerts. However, we still need to understand how this system affects medical expenses. Methods This study analyzed data from a […] ➡️➡️➡️

“`html Importance of Ultrasound Neuromodulation in Alzheimer’s Disease As dementia cases rise and treatment options remain limited, ultrasound neuromodulation presents a new potential therapy for Alzheimer’s Disease (AD). More research is needed to understand its full capabilities in treating brain disorders. Study Overview This study evaluated the effects of transcranial pulse stimulation (TPS) on patients […] ➡️➡️➡️

“`html Importance of Emergency Departments for Children’s Mental Health The emergency department (ED) plays a crucial role in helping children facing mental and behavioral health crises. It acts as a central point for families looking for support. Study Objectives This study aimed to assess the effects of a new mental health care approach on children’s […] ➡️➡️➡️

“`html Objective The study aimed to understand how the order of treatment—using stimulant medication and behavioral parent training—affects outcomes for children and mothers in families with multiple cases of attention-deficit/hyperactivity disorder (ADHD). Methods Mothers with ADHD and their children showing high ADHD symptoms participated in the study. Thirty-five mother-child pairs were randomly assigned to four […] ➡️➡️➡️

“`html Background and Objectives Chronic pelvic pain (CPP) is a common issue linked to pelvic inflammatory disease (PID). While acupuncture is often used to manage CPP, there hasn’t been enough research on using laser stimulation at specific acupuncture points. This study aimed to explore how laser treatment affects pain and quality of life in women […] ➡️➡️➡️