Clinical Trials

“`html Background and Objectives Fibromyalgia (FM) causes widespread chronic pain, stiffness, sleep issues, and fatigue. This study aimed to compare two recovery methods for improving sleep quality: a standard treatment in a hospital versus a relaxation therapy at home. Materials and Methods The study involved 60 adult patients diagnosed with FM. They were divided into […] ➡️➡️➡️

“`html Background and Objectives Prediabetes is a condition where blood sugar levels are higher than normal but not high enough to be classified as diabetes. This study looked at how a structured exercise program could improve health markers in inactive people with prediabetes over 16 weeks. Study Overview A 16-week randomized controlled trial was conducted […] ➡️➡️➡️

“`html Background and Objectives Clostridioides difficile infection (CDI) is a serious type of diarrhea often acquired in hospitals. This study looked at how the probiotic Bacillus licheniformis (B. licheniformis) can help maintain healthy gut bacteria in patients with CDI. Study Overview This research was conducted at six academic centers in Korea. It involved patients diagnosed […] ➡️➡️➡️

“`html Nutrients Study on Dysmenorrhea Dysmenorrhea is a condition that causes pain during menstruation and affects many women. This study looked at how probiotics and high-intensity interval training (HIIT) can help reduce the severity of dysmenorrhea. Study Overview Participants were divided into groups based on their condition: Control Group: No dysmenorrhea Dysmenorrhea Group: Experiencing dysmenorrhea […] ➡️➡️➡️

“`html Understanding Paroxysmal Sympathetic Hyperexcitation (PSH) Paroxysmal sympathetic hyperexcitation (PSH) is a condition that occurs after severe brain injuries, leading to sudden increases in sympathetic nervous system activity. This study explores how effective a treatment combining transcranial direct current stimulation (tDCS) and medication can be for PSH patients. Study Overview In this study, 40 patients […] ➡️➡️➡️

“`html Understanding Autism Spectrum Disorder (ASD) ASD is a condition that affects social interaction and can lead to repetitive behaviors. There is a need for new therapies that specifically target these behaviors. Study Overview This study investigates whether high-definition transcranial direct current stimulation (HD-tDCS) can help reduce these repetitive behaviors in children with ASD. It […] ➡️➡️➡️

“`html Clinical Trial Overview This study compared two methods for diagnosing chronic coronary syndrome (CCS) in patients experiencing chest pain. The methods were: Coronary Computed Tomographic Angiography (CCTA) followed by Invasive Coronary Angiography (ICA) Direct Invasive Coronary Angiography (ICA) Study Design A total of 1200 patients were included from TEDA International Cardiovascular Hospital between January […] ➡️➡️➡️

“`html Study Overview This study looks at how negative pressure wound therapy (NPWT) affects a small molecule called microRNA-155 (miR-155) in patients with diabetic foot ulcers (DFUs) and how this relates to wound healing. What We Did We involved 60 patients with DFUs, dividing them into two groups: one group received NPWT (40 patients) and […] ➡️➡️➡️

“`html Introduction Delirium is a common and serious condition in older patients in hospitals. It can lead to higher death rates, longer stays in the hospital, and problems with thinking. Researchers are looking into whether melatonin can help prevent delirium by improving sleep and regulating body rhythms. This study will see how well melatonin works […] ➡️➡️➡️

Background HIV transmission has risen in the U.S. among people who inject drugs. Testing for HIV and connecting individuals to treatment is essential for both personal and public health. However, many barriers prevent access to testing, even within programs designed to support this population. Study Overview This study will evaluate a new approach to improve […] ➡️➡️➡️

Objective: Vonoprazan is a new medication that helps treat Helicobacter pylori infections effectively. This study compares a 14-day treatment with vonoprazan and amoxicillin against personalized therapy based on drug sensitivity. Methods: In this study, 240 adults who did not respond to previous H. pylori treatments were randomly assigned to either the vonoprazan-amoxicillin treatment or the […] ➡️➡️➡️

Study Overview: This research focused on how effective pronase is in finding early cancer and improving visibility during gastroscopy in China. Study Details: 1450 patients were part of a program for early detection and treatment of upper gastrointestinal cancer. Patients were divided into two groups: one group received pronase and dimethicone, while the other group […] ➡️➡️➡️

Background: Using less or no opioids during anesthesia can help reduce pain after surgery. However, it’s not clear how different methods affect patients who are more sensitive to pain, especially during laparoscopic cholecystectomy (gallbladder surgery). Study Overview: In this study, 173 patients scheduled for gallbladder surgery were divided into three groups: one with no opioids […] ➡️➡️➡️

Title: A Randomized Trial to Evaluate a Co-Created Health Promotion Intervention for Immigrants with Type 2 Diabetes Introduction: Engaging end users can help overcome barriers to effective health promotion for type 2 diabetes. The DIABETHIC project, funded by the European Union and the Italian Ministry of Health, includes a multicenter randomized controlled trial (RCT) to […] ➡️➡️➡️

Study Overview: This research, published in the Australasian Journal on Ageing, examines how integrating artificial intelligence (AI) and virtual reality (VR) into art therapy can improve cognitive function and mental health in older adults with mild cognitive impairment. Research Methods: In a randomized controlled trial, 60 older individuals with mild cognitive impairment were divided into […] ➡️➡️➡️

Title: The Role of Long-Term Hair Steroids as Biomarkers in PTSD Background: Dysregulation of steroid hormones is often linked to the development of posttraumatic stress disorder (PTSD). However, applying these findings in clinical settings to assess symptoms and treatment effectiveness is challenging. There is a lack of long-term data on steroid levels during treatment. Objective: […] ➡️➡️➡️

Title: Evaluation of Renal Blood Flow Estimation Using Rubidium-82 PET/CT Background: Various techniques exist for estimating renal blood flow (RBF), but they have not been widely adopted in clinical practice due to their limitations. Our previous research indicated that rubidium-82 (82Rb) positron emission tomography/computed tomography (PET/CT) is a promising method for assessing renal perfusion. This […] ➡️➡️➡️

Recent research published in the Archives of Dermatological Research explored the effectiveness of carboxytherapy in managing acne flare while patients are undergoing treatment with oral isotretinoin for moderate to severe acne vulgaris. Oral isotretinoin is widely used to treat acne and prevent associated scarring and psychological issues. However, one of its side effects is an […] ➡️➡️➡️

Title: Analysis of MiRNAs as Biomarkers for Nutritional Therapy in Type 2 Diabetes Remission Abstract: Background: Type 2 diabetes mellitus (T2DM) is a significant global health issue. Achieving remission from this disease is possible; however, effective biomarkers for selecting the most suitable diet are limited. This study aims to evaluate the role of microRNAs (miRNAs) […] ➡️➡️➡️

Clinical Trial Results for HPV Treatment in Women Living with HIV Overview of the Study We conducted a clinical trial to see which method works better for treating HPV in women living with HIV. We compared two approaches: 1. **HPV screen and treat**: All HPV-positive women received treatment. 2. **HPV screen, triage, and treat**: Only […] ➡️➡️➡️