Dr M. Trenton

Background The TrialNet Oral Insulin (OI) prevention trial did not show a clear overall benefit when looking at type 1 diabetes as the main goal. However, a delay in the onset of diabetes was observed in a specific group of participants at high risk. Study Overview This analysis focused on a new approach to measure […] ➡️➡️➡️

Background Many studies show that psychotherapy can help people with posttraumatic stress disorder (PTSD). However, not everyone responds the same way to treatment, especially those with complex PTSD (CPTSD). We need better ways to match patients to the treatments that will help them the most. Objective The goal of this study was to create a […] ➡️➡️➡️

Background Since 1999, the standard treatment for locally advanced cervical cancer has been platinum-based chemoradiation (CRT). However, this treatment only improves overall survival by 6% over five years compared to radiotherapy alone. Many patients (30-40%) do not respond completely to CRT, indicating a need for better treatment options. New Approach A new method called Neoadjuvant […] ➡️➡️➡️

Overview of the Study This study focuses on a new treatment for primary central nervous system lymphoma (PCNSL), a type of blood cancer that is hard to treat due to the protective barrier in the brain. The treatment being tested is called the R-MO regimen, which includes rituximab, high-dose methotrexate, and orelabrutinib. Key Findings A […] ➡️➡️➡️

Background Cancer and its treatments can negatively impact fertility and sexual health. However, there are few proven ways to help those affected. This study introduces Fex-Can 2.0, an online program designed to support young adults with cancer by addressing fertility-related worries and sexual issues. Study Goals The main goal of this study is to see […] ➡️➡️➡️

Study Overview This study focused on understanding how reliable certain measurements are when using a specific exercise called the countermovement jump. It also looked at how well these measurements can show changes in strength after different training methods. Key Findings Twenty-one recreational runners participated in four different training sessions. Each session involved performing back squats […] ➡️➡️➡️

Importance of the Study The traditional treatment for tonsil issues in adults, called tonsillectomy (TE), often requires a long and difficult recovery period. Objective of the Study This study aimed to compare the long-term effectiveness and cost of a new treatment called carbon dioxide (CO2) laser tonsillotomy (TO) with the standard tonsillectomy. Study Overview The […] ➡️➡️➡️

Study Overview This study looked at a new type of medication called potassium-competitive acid blockers (P-CABs), specifically fexuprazan, to see how well it works for people with chronic cough related to gastroesophageal reflux disease (GERD). Study Details In this trial, adults with a chronic cough lasting at least 8 weeks and a recent diagnosis of […] ➡️➡️➡️

Background Treatment with fluocinolone acetonide, hydroquinone, and tretinoin cream is considered the best option for melasma. However, we need more information about how this treatment works for Chinese patients, as their skin may respond differently than that of Caucasian patients. Aim The goal of this study was to assess how effective and safe fluocinolone acetonide, […] ➡️➡️➡️

Objective The goal of this study was to prevent pain after thoracic surgery by using a new type of stitching technique that avoids damaging important nerves and blood vessels. Materials and Methods A clinical trial was conducted with 71 patients undergoing lung surgery using video assistance. These patients were divided into two groups: one received […] ➡️➡️➡️

Study Overview This analysis of the ATHENA trial looked at how dronedarone (400 mg twice daily) affects heart health in patients with early atrial fibrillation (AF) and other heart-related issues. Key Findings Fewer Serious Events: Patients taking dronedarone had fewer cardiovascular deaths, strokes, and hospitalizations due to heart failure or acute coronary syndrome compared to […] ➡️➡️➡️

Background Over the past 20 years, there has been significant progress in preventing the transmission of HIV from mothers to their babies, thanks to the widespread availability of antiretroviral therapy (ART). However, new infections in children still occur. Study Overview In a pilot study conducted in Lilongwe, Malawi, we tested a support package designed to […] ➡️➡️➡️

Background Many breast cancer patients experience depressive symptoms. A diet that reduces inflammation could help manage these symptoms. However, such diets can be expensive and hard to implement widely. Instead, teaching patients about anti-inflammatory diets could be a more affordable and effective solution. Study Overview We conducted a study to see how 12 weeks of […] ➡️➡️➡️

Cancer Clinical Trial Summary Background This study explored a new approach called the Comprehensive Oncology Rehabilitation and Exercise (CORE) algorithm. It aims to connect women diagnosed with breast cancer to exercise and rehabilitation services right from their diagnosis through their treatment journey. Methods The trial involved 72 women with early-stage breast cancer who needed surgery. […] ➡️➡️➡️

Clinical Trial Overview This clinical trial tested a new treatment for patients with newly diagnosed glioblastoma (GBM). It combined a drug called atezolizumab with radiation therapy and another drug, temozolomide (TMZ). The goal was to see if this combination helps patients live longer. Trial Details The trial involved 60 patients and aimed to measure overall […] ➡️➡️➡️

Study Overview This study focuses on treating IgA nephropathy, a kidney condition, using two medications: Enteric-coated Mycophenolate Sodium (EC-MPS) and hydroxychloroquine. The goal is to see if combining these two treatments is more effective than using hydroxychloroquine alone. What We Are Doing We are conducting a trial with 96 patients from 12 hospitals in Shanxi […] ➡️➡️➡️

“`html Background Children’s ability to use language is crucial for their education and overall development. Aims This study aimed to compare two language programs for preschoolers: Building Early Sentences Therapy (BEST) and Adapted Derbyshire Language Scheme (A-DLS). Methods We conducted a well-organized clinical trial with 20 early years settings, involving 102 children aged 3 to […] ➡️➡️➡️

Nutrients and Female Athletic Performance Hormonal changes during the menstrual cycle can affect female athletes’ physical performance, muscle function, and mental processing, especially before their period. This study looked at how dark chocolate (DC) could help. What is Dark Chocolate Good For? Dark chocolate is rich in beneficial compounds like flavonoids and magnesium. It may […] ➡️➡️➡️

Understanding Smoking Cessation for Lung Cancer Screening Patients Individuals who have lung cancer screening and continue to smoke face serious health risks. It’s vital to provide them with effective ways to quit smoking. This summary presents findings from a study that tested a smoking cessation program over 8 weeks. Study Overview The study involved 40 […] ➡️➡️➡️

Impact of the COVID-19 Pandemic on Mental Health The COVID-19 pandemic has increased feelings of depression due to social isolation and less physical activity. This situation highlights the need for easy-to-access remote treatment options for mental health. Overview of the SONRIE Study The SONRIE study looks at a 12-week online program that combines physical exercise […] ➡️➡️➡️