Dr M. Trenton

Purpose of the Study The study aimed to evaluate how well the Stockholm3 test predicts prostate cancer compared to other common tests and risk calculators. Study Overview This was a large trial conducted from 2019 to 2023, involving a diverse group of men who were eligible for prostate biopsy. A total of 2115 men participated, […] ➡️➡️➡️

Background Managing acute manic episodes in bipolar I disorder can be challenging due to drug resistance, which often leads to less effective treatments. This study explored whether adding folate and vitamin B6 to sodium valproate could help improve treatment outcomes for patients experiencing acute mania. Study Overview A total of 43 patients diagnosed with bipolar […] ➡️➡️➡️

Study Overview Aficamten is a new medication being tested to treat hypertrophic cardiomyopathy (HCM), a condition that affects the heart. This study looked at how aficamten affects the QTc interval, which is a measure of heart rhythm, in healthy people. Study Design The study had two parts: Part A: Involved 10 participants and aimed to […] ➡️➡️➡️

Background Digital mental health tools, including AI apps, are becoming popular for helping people with mental health issues. However, we need to understand how well these tools work for students who may be struggling. Objectives This study looked at two AI tools: GymBuddy, a fitness and accountability app, and Elomia, a mental health chatbot. We […] ➡️➡️➡️

Impact of Tele-Nursing on Mothers of Children with Epilepsy Epilepsy is a common neurological disorder affecting many children. A recent study explored how telephone support, known as tele-nursing, can help mothers manage their anxiety and improve their confidence in caring for their children after they leave the hospital. Study Overview The study involved 90 mothers […] ➡️➡️➡️

Study Overview This study investigates the use of a pulsed Er: YAG laser for treating erosive Oral Lichen Planus (OLP) and compares its effectiveness to Triamcinolone Acetonide (TA) ointment. Study Details Forty patients diagnosed with erosive OLP were divided into two groups: one received treatment with the Er: YAG laser, and the other with TA […] ➡️➡️➡️

Background Coronary Artery Bypass Graft (CABG) surgery helps patients with Coronary Artery Disease (CAD) live longer. However, low levels of essential trace elements in the body can negatively affect these patients. Objective This clinical trial aimed to see how taking trace element supplements affects recovery after CABG surgery. Methods Two hundred patients who had CABG […] ➡️➡️➡️

Clinical Trial on Pelvic Floor Sensory Testing This study focuses on understanding how pelvic floor sensory training can help women with stress urinary incontinence (SUI). It compares the sensory abilities of women with mild SUI to those of healthy women. Objectives The main goal is to evaluate the differences in pelvic floor sensation between women […] ➡️➡️➡️

Background Prostate cancer (PC) is common and can be overwhelming for patients. Choosing the right treatment, like surgery or radiation, is tough. Many patients look for support from others who have been through similar experiences. Online support groups (OSGs) have gained importance, especially during the COVID-19 pandemic. Study Objective This study explores how patients with […] ➡️➡️➡️

“`html Objective The goal of this study was to see how well an automated digital health program could lower the risk of developing Alzheimer’s disease compared to a control group that did not receive specific treatment. Background Over 300 million people globally may have brain changes that lead to Alzheimer’s disease long before they show […] ➡️➡️➡️

“`html Impact of Lemborexant on Daytime Sleepiness in Patients with Insomnia and Mild Sleep Apnea Objective This study aimed to see how lemborexant, a medication for insomnia, affects morning alertness in adults with both insomnia and mild obstructive sleep apnea (COMISA). Background COMISA can lead to daytime sleepiness and cognitive problems. Some sleep medications can […] ➡️➡️➡️

Understanding the Myasthenia Gravis Study Results Objective This study aimed to understand how well the Myasthenia Gravis (MG) Symptoms Patient-Reported Outcome (PRO) scale relates to other measures of daily living and muscle strength in patients with MG. We used data from a clinical trial called MycarinG. Background The MG Symptoms PRO is a new tool […] ➡️➡️➡️

Study Overview The INFRONT-3 study is a significant clinical trial that looks at a new treatment called latozinemab for frontotemporal dementia (FTD) caused by a specific gene mutation. This trial aims to understand how effective and safe latozinemab is for patients. Key Findings A total of 119 participants joined the study, with an average age […] ➡️➡️➡️

Objective We aimed to find out what factors can predict cognitive decline in older adults who are currently cognitively healthy over a 5-year period. Background Alzheimer’s disease varies greatly among individuals, making it challenging to design clinical trials and select the right participants. Understanding how to identify more similar groups can help improve trial outcomes. […] ➡️➡️➡️

Objective The goal of this study was to evaluate the safety of bemdaneprocel and its effects on health outcomes for people with Parkinson’s disease (PD) over a period of 24 months following transplantation. Background Bemdaneprocel is a new treatment being tested for Parkinson’s disease. It uses special cells derived from human embryonic stem cells. Previous […] ➡️➡️➡️

Objective The goal of this study was to see how ampreloxetine (a medication taken by mouth at 10 mg/day) affects supine hypertension, which is high blood pressure when lying down. This was measured using ambulatory blood pressure monitoring. Background Patients with certain neurological conditions often experience both low blood pressure when standing (neurogenic orthostatic hypotension […] ➡️➡️➡️

Research on Radial Artery Occlusion Prevention Background Radial artery occlusion (RAO) can occur after coronary procedures. This study explores how different access points and anticoagulation methods can help prevent RAO. Aims of the Study The study aimed to examine the effectiveness and safety of various radial access sites and the use of anticoagulation during coronary […] ➡️➡️➡️

Background Low-dose chest CT scans are now commonly used, leading to more patients being diagnosed with subsolid nodules (SNs). This study looks at how effective radio-frequency ablation (RFA) is for treating patients with pulmonary ground glass nodules (GGNs) and how it affects lung function. Study Overview We studied 100 patients diagnosed with pulmonary GGN between […] ➡️➡️➡️

Study Overview This study compared the effectiveness and safety of two types of anesthesia: liposomal bupivacaine (Lip-BPVC) and standard bupivacaine (BPVC). The focus was on patients undergoing heart surgery called coronary artery bypass grafting (CABG). Study Method A total of 82 adult patients were divided into two groups: one received Lip-BPVC and the other received […] ➡️➡️➡️

Clinical Trial Results for Xinbao Pill in Microvascular Angina Overview Coronary microvascular dysfunction is a growing concern, but effective treatments are still lacking. This study examined the effectiveness of the Xinbao pill for patients suffering from microvascular angina (MVA). Study Details A total of 200 patients with MVA were enrolled in this study between January […] ➡️➡️➡️