Clinical trials

“`html Study Summary Distress is common among cancer patients, and many do not receive the support they need. The study aimed to test the effectiveness of Mika, a digital app, in reducing distress in cancer patients. Methods Patients with cancer in Germany were enrolled in a trial. Participants were split into two groups: one using […] ➡️➡️➡️

“`html Study Overview Patients with atrial fibrillation (AF) who have had an ischemic stroke are at high risk for further clinical events. Taking direct oral anticoagulants (DOAC) is important for preventing these events, but some patients may not take their medication as prescribed. This study looked at how well stroke survivors with AF adhered to […] ➡️➡️➡️

“`html Study on Electroacupuncture for Diabetic Peripheral Neuropathy Background Diabetic peripheral neuropathy (DPN) is a common complication of diabetes, but current treatments have limitations. Electroacupuncture (EA) is being considered as an alternative treatment for DPN, but its effectiveness and safety are not well-established. Methods Searching for relevant studies in English and Chinese databases. Using RevMan5.3 […] ➡️➡️➡️

“`html Practical Solutions for Frequency Decomposition of Physiological Signals Summary Physiological processes often exhibit cyclical patterns, but analyzing these patterns can be challenging when the data is sparse and irregularly sampled. A new model called basis pursuit denoising with polynomial detrending (BPWP) has been developed to address this issue. It effectively recovers oscillations and trends […] ➡️➡️➡️

“`html Study on Dietary Screening Tool for Hypertension Risk in Nigeria Key Findings: Food frequency questionnaires (FFQs) can effectively assess dietary risks for hypertension in West Africa. The study involved 58 adult patients with hypertension, their caregivers, and 35 healthcare professionals from a Nigerian hospital. The 27-item FFQ was found to be easy to complete, […] ➡️➡️➡️

“`html Analysis of Antenatal Corticosteroid Prophylaxis Effectiveness Objective: Examine trends in effective antenatal corticosteroid prophylaxis (ACS) use for preterm birth-related diagnoses. Methods: Retrospective study using delivery data at Charité Berlin, Germany from 2014 to 2020. Evaluate the rate of effective ACS administrations (≤10 days before delivery) and the percentage of post-ACS deliveries at or after […] ➡️➡️➡️

“`html Telemedicine Program for Glaucoma Monitoring Key Findings: Glaucoma affects around 70 million people globally and is expected to impact up to 112 million by 2040. A telemedicine program was implemented to monitor glaucoma and glaucoma suspect patients during the COVID-19 pandemic. 11,034 telemedicine consults were conducted, with a high adherence rate of 99.8%. 49% […] ➡️➡️➡️

“`html Obstructive Sleep Apnea (OSA) and the Role of Telemedicine in CPAP Treatment Introduction: Obstructive sleep apnea (OSA) is a common sleep disorder linked to cardiovascular risk and daytime sleepiness. Continuous positive airway pressure (CPAP) is a treatment that keeps the airway open. Telemedicine in CPAP devices provides an alternative way for clinical staff to […] ➡️➡️➡️

“`html Disparities in Cancer Clinical Trials Enrollment in Canada A recent study examined the enrollment of new cancer patients in clinical trials at a large Canadian cancer center from 2006 to 2019. The study aimed to identify any disparities in enrollment and their potential impact on treatment access and outcomes. Key Findings: Overall, only 11.2% […] ➡️➡️➡️

“`html Summary of Recent Clinical Advances in Extraesophageal Reflux (EER) Management Purpose of Review: The study discusses the increasing challenges faced by clinicians in dealing with symptoms and complications related to extraesophageal reflux (EER) and highlights the latest clinical advances in understanding its causes, testing, and treatments for upper and lower airway issues. Recent Findings: […] ➡️➡️➡️

“`html Summary of Clinical Trial Report Background Neovascular age-related macular degeneration (nAMD) treatments require long-term follow-up of disease activity, which can be burdensome for patients and caregivers. Home-monitoring could alleviate this burden and free up clinic capacity. Objective The study aimed to assess the effectiveness of 3 vision home-monitoring tests in detecting active nAMD compared […] ➡️➡️➡️

Clinical Trial Report Reducing Quetiapine Use in Patients with Dementia Study Objective: To determine if warning letters to high prescribers of quetiapine can reduce its use among patients with dementia and to assess the impact on patients’ health outcomes. Key Findings: The intervention successfully reduced quetiapine use among both nursing home and community-dwelling patients with […] ➡️➡️➡️

Recombinant Zoster Vaccine (RZV) Study Study on Recombinant Zoster Vaccine (RZV) Background and Objective Researchers aimed to find out if the RZV vaccine could reduce the severity of herpes zoster cases in adults. Methods The study analyzed data from three clinical trials to compare the impact of RZV on the quality of life for vaccinated […] ➡️➡️➡️

“`html Study on Small Kidney Tumors Purpose To see if a new imaging technique, diffusion-relaxation correlation spectroscopic imaging (DR-CSI), can help identify different types and grades of small kidney tumors. Materials and Methods 61 patients with small kidney tumors were included in the study. MRI scans were analyzed using DR-CSI and apparent diffusion coefficient (ADC) […] ➡️➡️➡️

“`html Study Overview A recent clinical trial investigated the effects of synbiotics (probiotics and inulin prebiotics) on patients with pancreatic ductal adenocarcinoma (PDAC) to improve their immune response and reduce postoperative complications. The study compared the combined use of synbiotics versus probiotics alone on 90 PDAC patients. Key Findings The synbiotics group showed significant increase […] ➡️➡️➡️

“`html Enhanced Treatment for Relapsed T-lymphoblastic Leukemia/Lymphoma Patients with relapsed or refractory T-lymphoblastic leukemia/lymphoma (T-ALL/LBL) often face limited treatment options. A new study evaluated a combination therapy using daratumumab (Dara) and venetoclax (Ven) with aclarubicin, cytarabine, granulocyte colony-stimulating factor, and etoposide (CAGE) for these patients. Key Findings: The combined therapy showed a promising remission rate […] ➡️➡️➡️

Food and Gastrointestinal Symptoms in Irritable Bowel Syndrome (IBS) Solving the mystery of food triggers for IBS symptoms Key Points: Various dietary strategies aim to manage IBS symptoms. Study collected food intake and symptom diaries using a smartphone app. 70% of survey respondents had IBS according to Rome IV criteria. Strong associations found for certain […] ➡️➡️➡️

“`html Exercise Training for Hepatocellular Carcinoma Patients: A Systematic Review Background and Aim Patients with hepatocellular carcinoma (HCC) often experience reduced muscle mass and physical function, leading to higher health risks. This review aimed to assess the impact of exercise training programs on muscle mass and physical function in HCC patients. Methods Systematic search in […] ➡️➡️➡️

“`html Study Summary The study aimed to investigate the effectiveness and safety of using a combination of imaging techniques in treating wake-up stroke (WUS) patients. Methods Patients with WUS and specific imaging characteristics underwent either endovascular thrombectomy plus medical therapy or medical therapy alone. Functional outcomes were assessed using the modified Rankin scale (mRs) at […] ➡️➡️➡️

“`html Study Overview This study aimed to assess the impact of subthreshold micropulse laser (SML) in combination with anti-vascular endothelial growth factor (anti-VEGF) therapy for diabetic macular edema (DME). Research Methods Reviewed eight studies involving 493 eyes Four were randomized controlled trials and four were retrospective studies Utilized meta-analysis to analyze best-corrected visual acuity (BCVA), […] ➡️➡️➡️