Mediators of Change in Online Trauma Intervention Study Overview This study explores how early online interventions for trauma can help. It focused on a 3-week therapist-guided program that uses prolonged exposure therapy, comparing it to a waiting-list control group. Key Findings The research aimed to see if improvements in specific PTSD symptoms during the intervention…
A Comparative Study of Esketamine-Propofol vs Sufentanil-Propofol for Breast Surgery Study Overview This study investigates two anesthesia methods for patients undergoing breast surgery: esketamine-propofol and sufentanil-propofol. The goal is to find out which method is safer and more effective for pain relief and sedation. Study Purpose Minimally invasive rotary resection (MIRR) is vital for breast…
Clinical Trial Overview Objective: This study aimed to assess how effective and safe Buzhongyiqi pills (BZYQP) are in improving the appetite of colorectal cancer patients undergoing chemotherapy. Trial Design This was a pilot, randomized, single-blind cross-over clinical trial involving patients diagnosed with stage II-IV colorectal cancer receiving chemotherapy. Methods Participants were divided into two groups:…
The Impact of Baduanjin Exercise on Mental Health and Heart Rate Variability in College Students Study Overview This study looked at how a 16-week Baduanjin exercise program affected the mental health and heart rate variability (HRV) of college students who face challenges in sports. The goal was to see if this exercise could help improve…
Study Overview This research focused on how black tea drinks with inulin and dextrin (BTID) affect blood sugar levels in patients with type 2 diabetes (T2DM). It was a well-structured clinical trial comparing BTID to a placebo. Key Findings Significant Blood Sugar Control A total of 35 patients participated, with 32 completing the study. The…
Combined Mindfulness and Physical Activity for Better Mental Health Study Overview This study explored how combining mindfulness-based stress reduction (MBSR) and physical activity (PA) can enhance sleep quality and mental health in patients with Major Depressive Disorder (MDD). Key Findings Participants: 67 patients with MDD, averaging 35 years old, all on sertraline treatment. Groups: Patients…
Mindfulness Training for Children with ADHD Background Attention Deficit Hyperactivity Disorder (ADHD) is a common condition in school-aged children, characterized by inattention, hyperactivity, and impulsivity. Mindfulness training can help improve these symptoms and enhance emotional well-being, leading to a better quality of life. Aim The study aimed to explore how mindfulness training affects attention, impulsivity,…
Evaluation of Residual Carious Dentin Detection Methods Study Overview This study examines different methods for detecting leftover caries after tooth cavity preparation. The goal is to remove only the harmful caries while preserving healthy dentin. Methods Used The trial involved three methods: Visual-Tactile Method (Group A) Caries Detector Dye (CDD – Group B) Laser Fluorescence…
Self-Collection of Specimens for Chlamydia and Gonorrhea Testing Study Overview This study focused on whether self-collected samples could effectively diagnose Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections among men who have sex with men (MSM) in China. The goal was to make testing more accessible for those who hesitate to visit clinics. Key Findings…
Protocol Overview Study Title: Hyperbaric Oxygen Therapy (HBOT) for Treating Vaso-Occlusive Crisis (VOC) in Sickle Cell Disease (SCD) Publication: BMJ Open, November 2024 Introduction Sickle cell disease (SCD) is a common genetic disorder that affects many newborns and leads to serious complications, including vaso-occlusive crisis (VOC). VOC can cause severe pain and significantly reduce life…
iDiabetes Platform: Enhancing Diabetes Care in Scotland Introduction and Aim Diabetes is a major global health issue, leading to serious health problems and increasing deaths. One challenge is applying research findings to improve diabetes care. We propose a solution through a new digital platform called ‘intelligent Diabetes’ (iDiabetes). This platform aims to provide personalized diabetes…
A Study on Smoking Cessation Medication for Cancer Patients Purpose Many cancer patients continue to smoke even after their diagnosis. This study looks at their views on smoking cessation medications and why they may not be using them. Methods This analysis is based on the Smokefree Support Study. Out of 221 participants, 72 were chosen…
Comparison of NSAIDs and Corticosteroids for Temporomandibular Disorder Study Overview This study investigates the effectiveness of NSAIDs versus corticosteroid injections for treating Temporomandibular Disorder (TMD) caused by disc displacement without reduction. TMD can affect the joint and surrounding muscles, and its prevalence varies widely. The trial was conducted at Faisalabad Medical University in Pakistan over…
Large Language Models Enhance Medical Students’ Clinical Decision-Making Study Overview This study examines how Large Language Models (LLMs) can improve medical students’ clinical decision-making (CDM) through patient simulations and feedback. Key Findings We developed AI prompts that simulate patients with various symptoms for realistic medical conversations. In our trial: The control group had simulated conversations…
New Insights from the Second Revision of the International Staging System Overview of the Study The International Staging System for multiple myeloma has been updated to include new factors that affect patient prognosis. This update, called R2-ISS, enhances our understanding of multiple myeloma by considering additional high-risk features. Study Findings In the ICARIA-MM and IKEMA…
Cost-Effectiveness of C-Reactive Protein Testing for Antibiotic Use in COPD Study Overview This study evaluated the use of C-reactive protein point-of-care testing (CRP-POCT) to help reduce unnecessary antibiotic prescriptions in patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD). Excessive antibiotic use can lead to waste, antibiotic resistance, and potential harm to patients. Research…
Internet-Delivered Psychoeducation (SCOPE) for Transition-Aged Autistic Youth Study Overview The SCOPE program is an 8-week online psychoeducation intervention designed for autistic youth. This study tested its effectiveness through a randomized controlled trial. Goals of the Study The main goal was to see if SCOPE could help participants better understand autism and improve their quality of…
Impact of a Dynamic Orthosis on Manual Dexterity in Parkinson’s Disease Importance of the Study A dynamic elastomeric fabric orthosis may offer a new non-drug treatment for motor symptoms in people with Parkinson’s disease (PD). Study Objective The goal was to assess how effective the orthosis is in improving manual dexterity in individuals with PD.…
Transverse vs. Longitudinal Skin Incision in Surgery for De Quervain’s Tenosynovitis Study Overview De Quervain’s tenosynovitis causes pain and swelling near the wrist. When non-surgical treatments fail, surgery is often needed. This study compared two surgical techniques: transverse and longitudinal skin incisions, focusing on scars, pain, and recovery. Methodology Seventy patients were randomly assigned to…
Controlling Resting Heart Rate in Patients with Atrial Fibrillation and Coronary Heart Disease Study Overview Current guidelines suggest keeping the resting heart rate below 100-110 beats per minute (bpm) for patients with atrial fibrillation (AF). However, there is little research on treating patients with both atrial fibrillation and coronary heart disease (AF&CHD). Key Findings We…