Clinical trials

Overview of the CONNACT Trial The CONNACT trial looked at a new way to help people with knee osteoarthritis by combining care from orthopedic doctors and other health professionals in the community. This study aimed to see how well this approach worked and how it could be used in real life. What Worked? Physical Performance: […] ➡️➡️➡️

Understanding the Importance of Foot Care for People with Diabetes Diabetes can lead to serious health problems, including issues with the feet. Many people living in the slums of Karachi, Pakistan, do not know how to take care of their feet, which can result in painful ulcers and even amputations. This not only affects their […] ➡️➡️➡️

Understanding the Trial Results The study tested a new system called Hypotension Prediction Index (HPI) Smart Alerts to help doctors better manage blood pressure during major surgeries. The goal was to see if these alerts would make it easier for medical teams to follow important steps in patient care called Goal-Directed Hemodynamic Therapy (GDHT). What […] ➡️➡️➡️

Purpose of the Study This study looked at how adding a treatment called dexamethasone (Ozurdex) to surgery for patients with a severe eye condition called proliferative diabetic retinopathy (PDR) and retinal detachment (RD) can help improve their outcomes. What Was Done? The study involved 30 patients who needed a specific eye surgery called vitrectomy, where […] ➡️➡️➡️

Understanding the Study Results This study looked at how virtual reality (VR) exercises can help people with lumbar disc herniation, which is a common back problem that causes pain and makes daily activities difficult. The results showed that: Less Pain: People who did VR exercises reported a big drop in their pain levels. Improved Daily […] ➡️➡️➡️

Understanding the Study Results for Trigger Finger Treatment Trigger finger can be painful and make it hard to use your hands. This study looked at two ways to treat it: a procedure called percutaneous release and steroid injections. What Worked? Percutaneous Release: This treatment showed better results in improving hand function and reducing pain compared […] ➡️➡️➡️

Understanding the Study This study looked at three different ways to collect samples from lymph nodes in the chest using a technique called Endobronchial Ultrasound (EBUS). This is important for diagnosing conditions related to swollen lymph nodes. Main Findings Researchers compared: Slow-pull capillary sampling Traditional negative-pressure aspiration Non-negative-pressure capillary sampling The results showed: All three […] ➡️➡️➡️

Understanding the Study on Probiotics and Omega-3 for Type 2 Diabetes This research looked at how well a combination of probiotics and omega-3 fatty acids works for people with type 2 diabetes (T2D). The goal was to see if this combination could help improve the function of insulin-producing cells in the pancreas. What the Study […] ➡️➡️➡️

Understanding the Study Results The study looked at how well different tools help preserve tooth structure during a procedure called pulpectomy in children’s back teeth. The tools compared were: The naked eye Surgical loupes (magnifying glasses) A dental operating microscope (DOM) What Worked? Dental Operating Microscope (DOM): This tool helped keep more of the tooth […] ➡️➡️➡️

Understanding the Study Results This study looked at how willing primary care professionals (PCPs) are to treat patients with opioid use disorder (OUD) compared to those with type 2 diabetes. The results showed: Willingness to Treat: PCPs were more willing to treat type 2 diabetes than OUD. They rated their willingness to treat diabetes at […] ➡️➡️➡️

Understanding the Research Findings This study examined two tools, the Good Outcome Following Attempted Resuscitation (GO-FAR) score and the Clinical Frailty Scale (CFS), to see how well they predict long-term survival in hospitalized patients. The study included 2,840 patients in Swiss hospitals. What Worked? The GO-FAR and CFS efficiently identified patients at risk of dying […] ➡️➡️➡️

Understanding the Trial Results This trial looked at how “brain frailty” affects recovery after a stroke treated with a medication called thrombolysis. Brain frailty means the brain has damage that makes it weaker and less able to recover from injuries like strokes. What Worked? Patients with less brain frailty had better recovery outcomes. The trial […] ➡️➡️➡️

Understanding the Results of the Colorectal Cancer Screening Trial What Was the Trial About? The SAVE trial studied two ways to screen for colorectal cancer (CRC): CT Colonography (CTC), which is a special type of X-ray, performed every 5 years. Fecal Immunochemical Tests (FIT), which are simple tests done every 2 years at home. The […] ➡️➡️➡️

Understanding the Study Results This study looked at how two types of cheese—Jarlsberg and Norvegia—affect Nordic skiers’ muscle strength and endurance during their training period. Here’s what we found: What Worked? Both types of cheese, when combined with off-season training, improved muscle strength, lean body mass (LBM), and VO₂ max (a measure of endurance). There […] ➡️➡️➡️

Understanding the Study Results on Wheat Sensitivity What Was the Study About? This study looked at nonceliac wheat sensitivity (NCWS) in patients with irritable bowel syndrome (IBS) or functional dyspepsia (FD). These patients often have stomach issues that don’t respond to usual treatments. The researchers wanted to find out how common NCWS is among these […] ➡️➡️➡️

Main Findings of the Study The study looked at how two treatments—using acupoint application and electrical stimulation—could help patients recover after a gastroscopy, which is a procedure to examine the stomach. The results show that combining these treatments helped patients recover faster and feel better overall. What Worked Patients who received the new treatment had […] ➡️➡️➡️

Understanding the Trial Results The recent study looked at how well a new treatment plan works for patients with a type of breast cancer called HER2-negative inflammatory breast cancer (IBC). This treatment plan included a drug called eribulin along with doxorubicin and cyclophosphamide. What Worked? All patients were able to have surgery to remove their […] ➡️➡️➡️

Understanding the Trial Results This study looked at how ozonated olive oil can help patients with diabetic foot ulcers (DFUs). DFUs are serious wounds that can lead to infections and sometimes amputations. The trial involved 123 adults with type-2 diabetes and wounds classified as Wagner grade 1-2. What Worked? Wound Healing: Patients using ozonated olive […] ➡️➡️➡️

Understanding the Study on Vitamin D and E for Menstrual Pain Relief This study looked at how taking vitamin D and E supplements can help people with primary dysmenorrhea, which is a condition that causes painful menstrual cramps. Here’s what the research found and how it can help patients and clinics. What Worked? Pain Relief: […] ➡️➡️➡️

Understanding the Study Results This study looked at a new tool used during colonoscopy, which is a procedure to check the colon for polyps (small growths that can become cancerous). The goal was to see if this new tool could help doctors find more polyps compared to the standard method. What Worked? The new tool […] ➡️➡️➡️