Clinical trials

Understanding the MovingTogether Trial Results The MovingTogether trial looked at how a digital program could help improve mental health for older adults. Here’s what we found: What Worked? The MovingTogether program helped reduce feelings of psychological distress in participants aged 60 and older. Participants who used the program reported feeling better mentally compared to those […] ➡️➡️➡️

Understanding the Study on Patient Safety Education This study looked at how teaching nursing students about patient safety through peer education affects their skills and attitudes towards medical errors. What Happened in the Study? Sixty-two nursing students were split into two groups: Control Group: Received standard patient safety education. Intervention Group: Learned through a peer […] ➡️➡️➡️

Understanding the M-Cardio Mobile App Study Who Was Involved? This study looked at 244 patients in Kyrgyzstan who have chronic heart failure (CHF). These patients were divided into two groups: Main Group: 127 patients used the M-Cardio mobile app for remote monitoring. Control Group: 117 patients received standard care without the app. What Is the […] ➡️➡️➡️

Trial Results Explained This study looked at whether a medicine called sumatriptan can stop migraines caused by a specific drug, levcromakalim. Here’s what we found: What Worked? Sumatriptan did not stop migraines from happening after levcromakalim was given. However, sumatriptan did help reduce the intensity of headaches once they started. What Didn’t Work? There was […] ➡️➡️➡️

Main Findings of the Study Researchers compared two pain relief medications, nalbuphine and sufentanil, during a specific type of surgery called hysteroscopy. They wanted to see which drug needed less of a commonly used anesthetic, propofol, to manage patients’ reactions to cervical dilation, which is a part of the procedure. What Worked? Nalbuphine (0.2 mg): […] ➡️➡️➡️

Understanding the Decompression-Plus Trial The Decompression-Plus trial is a research study aimed at finding new ways to help people with serious spinal cord injuries. This study looks at a method called dorsal myelotomy and expansive duroplasty (DMED), with or without using a patient’s own nerve tissue (autologous nerve grafting or ANGI). The goal is to […] ➡️➡️➡️

Study Overview This study looked at a simple and engaging safety training program designed to help prevent unintentional injuries in preschoolers living in rural China. It took place in 12 preschools and involved over 2,500 children aged 3 to 6 years old. What Worked? The program, which included interactive learning in a special “Safety Experience […] ➡️➡️➡️

Understanding the Study Results This study looked at how celecoxib, a medication, can help prevent a common side effect of capecitabine, which is a chemotherapy drug used to treat colorectal cancer. The side effect is called hand-foot syndrome (HFS), which causes pain and discomfort in the hands and feet. What Worked? The group of patients […] ➡️➡️➡️

Understanding the Study Results This study looked at how different types of straw phonation (SP) therapy can help female speech-language pathology (SLP) students with mild voice problems (dysphonia). The researchers wanted to see if these therapies worked in the short term (right after treatment) and longer term (three months later). What Worked? The therapy using […] ➡️➡️➡️

Understanding the Trial Results This study looked at how effective a test called urodynamics is for women with a very common problem called overactive bladder. This condition can make you feel like you need to urinate often, sometimes leading to accidents. When other treatments don’t work (which happens in 25-40% of cases), doctors usually suggest […] ➡️➡️➡️

Understanding the UPSTREAM Trial Results What Was the Trial About? The UPSTREAM trial looked at whether a special test called urodynamics, which is invasive, could help older men with troublesome urinary symptoms. The goal was to see if these tests would lead to better treatment and fewer surgeries. Key Findings No Major Improvements: After 5 […] ➡️➡️➡️

Understanding the Study on Pleural Needle Biopsies What Was the Study About? This study looked at two types of needles used in ultrasound-guided pleural needle biopsies. These biopsies help doctors diagnose problems in the pleura, the lining around the lungs. The two needle types are: Abrams needle Cutting needle The study aimed to find out […] ➡️➡️➡️

Understanding the Trial Results This study looked at a system called RoSCo, designed to help doctors assess the surgical risks for patients before they have robot-assisted kidney surgery for cancer. The goal was to see if using this system could help patients recover faster after their surgery. What Worked? Patients who followed the RoSCo-guided plan […] ➡️➡️➡️

Understanding the Trial Results: Endobiliary Radiofrequency Ablation for Cholangiocarcinoma What Was the Study About? This study looked at a new treatment called endobiliary radiofrequency ablation (EBRFA) for patients with a type of cancer called unresectable perihilar cholangiocarcinoma (pCCA). This cancer often leads to jaundice, which is a yellowing of the skin due to blocked bile […] ➡️➡️➡️

Trial Results Explained This trial looked at two treatments for older adults with severe aplastic anemia (SAA), a serious blood condition. The two treatment groups were: Group 1: Antithymocyte globulin (ATG) + cyclosporine A (CsA) + avatrombopag (AVA) Group 2: Cyclosporine A (CsA) + avatrombopag (AVA) After studying 84 patients, here’s what we found: The […] ➡️➡️➡️

Understanding the Study Results What Was Tested? This study compared two methods for treating teeth with large root canals that haven’t fully developed: Novel Apical Barrier Technique (N-ABT): Uses 3D printing technology to create custom tools and accurately measure filling material. Traditional Apical Barrier Technique (T-ABT): Uses a standard tool without precise volume measurement. What […] ➡️➡️➡️

Understanding the Study Results This study looked at two treatment options for patients with locally advanced borderline resectable oral cavity cancer (OCC). The goal was to see which approach worked better in helping patients before and after surgery. What Worked? Neoadjuvant Chemoradiotherapy (NACRT): This treatment before surgery showed promising results. Out of the patients who […] ➡️➡️➡️

Understanding the Trial Results This study looked at how a special device can help people who have had a moderate to severe stroke regain use of their arms and hands. Many stroke survivors struggle with using their arms, which makes daily activities hard. The trial tested a new device that helps with arm movement and […] ➡️➡️➡️

Who Should Read This?Doctors and patients interested in treatments for lower back pain. What Was the Study About?This study looked at how effective a shot of betamethasone (a type of glucocorticoid) is for people with lumbar radicular pain (pain that travels down the leg from the lower back). What Happened in the Study? – Participants: […] ➡️➡️➡️

Background Chronic kidney disease of uncertain etiology (CKDu) is a health issue mainly affecting farmers in North Central Province, Sri Lanka. Many patients do not feel sick until the disease is quite severe. As it gets worse, patients can face other health problems like anemia and heart issues. Taking too many medications can make it […] ➡️➡️➡️