Clinical trials

Background There are currently no established methods for including trauma-informed care in prenatal services. This study looks at what pregnant individuals prefer regarding their prenatal care, providers, and how trauma is addressed. Methods This research was part of a larger clinical trial and took place in a health center and clinic in a big city. […] ➡️➡️➡️

Clinical Trial Overview This study compares two methods for locating ground glass opacity (GGO) in the lungs during surgery: the Geometric Localization Technique (GLT) and the CT-guided Percutaneous Localization Technique (CPLT). The goal was to determine which method is more effective, safe, and accurate. Study Details A total of 455 patients diagnosed with pulmonary GGO […] ➡️➡️➡️

“`html Background In patients with swollen lymph nodes in the head and neck area, finding the original tumor site helps doctors target radiotherapy more accurately. This can lead to better treatment outcomes by reducing unnecessary radiation exposure to healthy tissues and lowering side effects. Current methods, including advanced imaging and surgery, can identify the primary […] ➡️➡️➡️

Study Overview This study compares the effectiveness of two types of biologic treatments, IL-17 and IL-23, for patients with plaque psoriasis, especially those with metabolic syndrome (MetS). It also looks at how these treatments affect metabolic health indicators. Study Details The research involved 120 patients with moderate to severe plaque psoriasis. Half of the patients […] ➡️➡️➡️

Background Recent studies show that diet and exercise can help people with type 2 diabetes (T2DM) improve their health. This research also suggests that the immune system may play an important role in this process. Study Overview This study looked at 183 newly diagnosed T2DM patients who were not on any glucose-lowering medications. They were […] ➡️➡️➡️

Introduction Type 2 diabetes is much more common in people with severe mental illness than in the general population. Helping these individuals manage their diabetes is crucial for better health outcomes. The DIAMONDS trial is designed to test a new program that supports diabetes self-management for people with both Type 2 diabetes and severe mental […] ➡️➡️➡️

Background There are few effective treatments for older patients with acute myeloid leukemia (AML). A study was done to test a new treatment combining pegylated liposomal doxorubicin (PLD), low-dose cytarabine (LDAC), and granulocyte colony-stimulating factor (G-CSF) for elderly patients newly diagnosed with AML. Study Details Twenty-two patients were included in the study. The average age […] ➡️➡️➡️

Background Caregivers of people with Alzheimer’s disease often overlook their own health, especially their stress levels. This is particularly true for African American women, who are at higher risk for high blood pressure. Ongoing stress from caregiving and high blood pressure increases the risk of heart disease. It’s important to address stress to improve caregivers’ […] ➡️➡️➡️

Background Research shows that primary care can help manage chronic diseases, even in places with limited resources. However, we need to understand the long-term effects of these interventions. This study looked at a program called SINEMA, which used technology to help stroke patients, and how it affected their survival rates six years after the trial […] ➡️➡️➡️

Study Overview This study evaluates the effectiveness of different energy sources used in a procedure called en-bloc transurethral resection of bladder tumors (ERBT). The goal is to understand how these methods impact patient outcomes during and after surgery. Methods The research analyzed data from a clinical trial involving patients who underwent ERBT or conventional transurethral […] ➡️➡️➡️

Purpose of the Study This study aimed to find a better way to analyze microperimetry data, which helps evaluate the effectiveness of gene therapy for inherited retinal diseases (IRDs). Methods We looked at data from a phase II trial of AGTC-501 in patients with X-linked retinitis pigmentosa (XLRP). We used a special device called the […] ➡️➡️➡️

Study Overview This study aimed to compare the effectiveness of two types of 0.05% cyclosporine eye drops—an aqueous solution and an oil emulsion—in treating patients with moderate-to-severe dry eye disease. Study Design The research was a prospective randomized clinical trial involving 88 patients who were divided into two groups. One group received the aqueous solution, […] ➡️➡️➡️

Introduction Testing for HIV among male partners of pregnant women is crucial for better health outcomes for everyone involved. However, many men in Africa still do not get tested. This study looked at how male peer outreach can help increase HIV testing rates in Uganda. Study Overview We conducted a trial in Kampala, Uganda, with […] ➡️➡️➡️

Study Overview This study looked at the effects of Salvia officinalis (also known as sage) on women with Polycystic Ovary Syndrome (PCOS). It aimed to see how this herb could help with metabolism and reduce oxidative stress in patients. Study Details The research was conducted in gynecology clinics in Iran. A total of 70 married […] ➡️➡️➡️

Background Antibiotics before cesarean delivery are generally recommended for all patients, but there are concerns about their effects on infants. This study tested the processes of a clinical trial involving low-risk women receiving either cefazolin (an antibiotic) or a placebo before elective cesarean delivery. Methods The trial was registered and included women aged 18 to […] ➡️➡️➡️

Background Head lice are common worldwide, especially in rural areas with lower incomes. They cause severe itching and can lead to infections that may have serious health effects. Ivermectin is effective against head lice and is also being tested for malaria prevention. This study looked at the causes of head lice and evaluated the effectiveness […] ➡️➡️➡️

Background Standard treatment for early triple-negative breast cancer (eTNBC) often includes anthracycline-containing chemotherapy, which can have serious side effects. This study looked at tumor biopsies to find gene networks that could help predict treatment success and survival after a different type of chemotherapy that doesn’t use anthracyclines. Study Methods In the WSG-ADAPT-TN trial, patients with […] ➡️➡️➡️

Background Breast cancer (BC) is the most common cancer among women worldwide. Early detection is crucial, and Breast Self-Examination (BSE) plays a key role in this process. This study aimed to evaluate how effective face-to-face and virtual education on BSE is, using the theory of planned behavior (TPB). Study Overview This randomized controlled trial involved […] ➡️➡️➡️

Overview of the Study The study focused on a new laser treatment for acne called the 589/1319 nm solid-state dual-wavelength (SSDW) laser. This laser is designed to reduce inflammation and oil production in acne without needing extra dyes. Study Details Eighteen patients with acne on both sides of their faces participated in the study. They […] ➡️➡️➡️

Overview of the Study This study focused on breast cancer survivors who often face long-lasting symptoms such as anxiety, stress, insomnia, menopausal symptoms, and cognitive issues. The goal was to find effective non-drug solutions to help these individuals. Study Method We conducted a three-part trial with 60 women in the UK who had a history […] ➡️➡️➡️