Clinical trials

Understanding the Impact of Group Music Therapy on Women with Depression What is Major Depressive Disorder (MDD)? Major depressive disorder is a serious mental health condition that affects many women. It is often linked with high levels of stress. Music Therapy as a Treatment Music therapy has been found to help women with MDD. It […] ➡️➡️➡️

Background Idiopathic pulmonary fibrosis (IPF) is a lung disease that often affects older adults, leading to depression in many patients. This study investigates whether treating depression can help slow down the worsening of IPF and related health issues in elderly patients. Methods The study involved elderly patients (over 60 years old) diagnosed with IPF who […] ➡️➡️➡️

Introduction Caudal epidural block is a common procedure used to manage pain after surgery in children. This technique involves injecting a local anesthetic that can affect the brain and spinal fluid. Study Overview This study focused on children aged 1-7 years who were undergoing surgery. They were divided into two groups: one received a caudal […] ➡️➡️➡️

Study Overview This study looked at how high-definition transcranial direct current stimulation (HD-tDCS) can help children with autism spectrum disorder (ASD) who have issues with sensory processing. It involved 72 children with ASD, divided into groups based on their sensory integration abilities. Key Findings 1. Improvement in Social Skills: Children with typical sensory integration showed […] ➡️➡️➡️

Unhealthy Alcohol Use and Its Impact Unhealthy alcohol use (UAU) leads to significant health issues and more than 140,000 deaths annually in the US. Routine screening for UAU in adults and pregnant individuals is strongly recommended to provide necessary support and prevent further health risks. Study Overview A study was conducted in Colorado to explore […] ➡️➡️➡️

Study Overview This study explores how patients view using music to manage pain. While many healthcare providers support this idea, patients’ opinions and experiences are less understood. The goal is to learn about patients’ attitudes towards music as a pain relief method and how it can be effectively used in healthcare. Study Design The research […] ➡️➡️➡️

Background Access to pre-exposure prophylaxis (PrEP) is crucial for reducing HIV cases in the U.S. However, certain groups, such as young people and minorities in North Carolina, are not using PrEP as much as they should. In 2018, the South had over half of new HIV diagnoses but only a third of PrEP users. This […] ➡️➡️➡️

Introduction DREAMS-START is a program designed to help people with dementia who have trouble sleeping. This study looked at how well the program worked and what factors influenced its success. Methods We used a mix of methods to gather information. We checked how well participants followed the program and interviewed family members and facilitators involved […] ➡️➡️➡️

Background High blood pressure (BP) is a widespread issue, affecting about one-third of people globally. Poor sleep quality can increase the risk of high BP, but this is something we can improve. Yoga may help lower BP, but we need more information about how long and how intense the sessions should be. This study aims […] ➡️➡️➡️

Clinical Comparison of Lithium and Quetiapine for Depression This study examined whether quetiapine is better than lithium for patients with treatment-resistant depression over a year. Treatment-resistant depression is when standard antidepressants don’t help enough. Study Overview The trial involved 212 adults from six NHS trusts in England, who were experiencing major depressive disorder. They had […] ➡️➡️➡️

“`html Background Adipose extracellular matrix/stromal vascular fraction gel (ECM/SVF-gel) is a treatment that includes stem cells and other components from fat tissue. It helps produce collagen and can fill in scars. Aim This study aimed to compare the effectiveness and safety of ECM/SVF-gel injections for treating acne scars with CO2 fractional laser (CO2FL) treatments. Methods […] ➡️➡️➡️

Introduction Recent studies have compared aggressive treatments for prostate cancer (PCa) with monitoring approaches. While aggressive treatments show slight survival benefits, they can significantly lower quality of life. A new method called MR fusion cryoablation (MRFC) is showing promise. This study looks at men diagnosed with prostate cancer through a specific biopsy method and treated […] ➡️➡️➡️

Background Traditional treatments for Raynaud’s phenomenon (RP) often don’t work well because they don’t address all the causes of the condition. This study looks at a new treatment that combines high-density fat grafting (HDFG) with botulinum toxin A (BTX-A) to see if it can help patients better. Study Overview Eleven patients with 20 affected hands […] ➡️➡️➡️

Background Stroke is a major cause of disability and death around the world, especially in poorer countries. Many people with high blood pressure and diabetes do not manage their conditions well. In Nigeria, less than 50% of patients take their medications as prescribed. This study looks at whether sending text message reminders can help patients […] ➡️➡️➡️

“`html Introduction The elderly are at higher risk of severe illness and death from COVID-19. About 20% of older adults may not have antibodies three to five months after their second COVID-19 vaccine dose. This study investigates whether probiotics can help boost antibody levels after vaccination. Study Overview This study is a randomized controlled trial […] ➡️➡️➡️

Study Overview This study aimed to assess how effective and safe a treatment called sonolysis is when used during a surgical procedure known as carotid endarterectomy. The research was conducted across 16 centers in Europe and involved 1,004 patients, with an average age of 68 years. What is Sonolysis? Sonolysis uses low-intensity ultrasound waves to […] ➡️➡️➡️

Background Adolescents in Sub-Saharan Africa face a serious challenge with HIV, and many also struggle with depression. This can make it hard for them to stay engaged in their HIV care. We are testing two versions of the Friendship Bench program in Malawi to see if they can help reduce depression and improve care for […] ➡️➡️➡️

Background The European guidelines recommend using digital mammography (DM) or digital breast tomosynthesis (DBT) for screening women who are at average risk for breast cancer. A study called IMPETO in Tuscany, Italy, is looking into how effective DBT is for screening. There is not much information about how women feel about this new technology, so […] ➡️➡️➡️

Understanding the Impact of Apalutamide in Prostate Cancer Treatment Background Research has shown that the effectiveness of apalutamide, a drug for treating metastatic castration-sensitive prostate cancer (mCSPC), may vary based on the number of bone metastases a patient has. Study Overview This study analyzed data from 1,052 patients who participated in the TITAN trial, comparing […] ➡️➡️➡️

Clinical Trial Summary Study Overview This clinical trial looked at how selective caries removal in deep cavities affects tooth sensitivity, pulp health, and new dentin formation. The study also examined the effects of using a specific type of light therapy called photobiomodulation (PBM). Methods Twenty-seven permanent molars with deep cavities were divided into three groups: […] ➡️➡️➡️