Clinical trials

Understanding the Link Between Dietary Fatty Acids and Ovarian Cancer Purpose: There is ongoing debate about how dietary fatty acids (FAs) may affect the risk of ovarian cancer (OC). This study aimed to clarify this relationship using data from a large group of women. Study Overview Methods: The research included women from the Prostate, Lung, […] ➡️➡️➡️

Background Disseminated histoplasmosis is a serious infection that can be life-threatening, especially for people with advanced HIV. Diagnosing this condition can be challenging due to unclear symptoms and limitations in traditional testing methods. Study Objectives This study looked at chest CT scans of patients with disseminated histoplasmosis and advanced HIV to identify common patterns that […] ➡️➡️➡️

Understanding the Crisis Opioids are a leading cause of overdose deaths in the USA, creating a significant public health issue. Many patients also struggle with mental health disorders, which complicate treatment efforts and lead to worse outcomes. Collaborative Care Approach Collaborative care has been shown to improve treatment for individuals dealing with both substance use […] ➡️➡️➡️

Understanding Bone Health in Parkinson’s Disease Parkinson’s disease (PD) increases the chances of falling and developing osteoporosis, which raises the risk of fractures. Recent guidelines suggest that those with PD should undergo a risk assessment, like the FRAX tool, but current treatment pathways are not very effective. To improve this, we created a specific algorithm […] ➡️➡️➡️

Overview of the Study Smoking significantly increases the risk of developing chronic obstructive pulmonary disease (COPD), contributing to 80% of cases. One of the early signs of COPD is reduced physical ability, which is linked not only to lung function but also to issues with the musculoskeletal system. Study Goals The study aimed to compare […] ➡️➡️➡️

Effects of Acupuncture on Bell’s Palsy This study looked at how acupuncture can help patients with Bell’s facial paralysis during the early stages of their condition. We tested this using a method called surface electromyography to measure muscle strength and fatigue in the face. Study Overview Sixty patients with acute Bell’s palsy were divided into […] ➡️➡️➡️

“`html Background Infections from wounds can be tough to treat, especially with bacteria becoming resistant to common antibiotics. This highlights the need for new treatment methods that are proven effective through reliable testing. Objective This study aimed to evaluate how well phage therapy works compared to traditional treatments for patients with various types of surgical […] ➡️➡️➡️

Background The iCAN mobile health program aims to help people experiencing homelessness by improving their access to healthcare and reducing visits to hospitals and emergency rooms. Objective This study evaluates the costs and financial benefits of the iCAN program through three main analyses: cost analysis, cost-benefit analysis, and budget impact analysis. Methods We gathered financial […] ➡️➡️➡️

Background Patients with a high risk of bleeding often have complicated heart artery issues. This study looked at whether using advanced imaging during heart procedures (called PCI) helps these patients more than traditional imaging methods. Study Overview This research was part of a larger trial called RENOVATE-COMPLEX-PCI, which took place in Korea from May 2018 […] ➡️➡️➡️

Overview of the Clinical Trial A recent clinical trial in Japan explored the use of rituximab, a treatment for membranous nephropathy with nephrotic syndrome, without steroids or immunosuppressants. This study involved 88 patients and compared the effects of rituximab against a placebo. Study Design This was a multicenter trial, taking place at 15 locations in […] ➡️➡️➡️

Aim of the Study This study aimed to compare the effectiveness of using laser treatment combined with sinus curettage against using curettage alone for treating pilonidal sinus disease (PSD). We looked at postoperative complications, how well wounds healed, and the chances of the disease coming back. We also wanted to find out what factors might […] ➡️➡️➡️

Study Overview This study looked at how adults with higher body weights face weight stigma in healthcare settings and how a specific strategy can help. The strategy involves using an “identity-safety cue,” which shows that a person’s social identity is valued. Study Details A total of 527 adults in the U.S. who identified as overweight […] ➡️➡️➡️

“`html Importance of Colorectal Cancer Screening About 60 million adults live in rural areas of the US, where many do not get screened for colorectal cancer (CRC). This is especially true for those on Medicaid. Study Objective The goal of this study was to see how effective a program was that used mailed tests and […] ➡️➡️➡️

Background Immune checkpoint blockade (ICB) is a treatment that works well for some patients with head and neck squamous cell carcinoma (HNSCC), but many do not respond to it. Study Overview In a recent clinical trial, patients with recurrent or metastatic HNSCC who did not respond to ICB were given a low dose of a […] ➡️➡️➡️

Understanding Insulin Resistance in Adolescents This study looks at how insulin resistance (IR) affects teenagers with obesity, especially focusing on fat tissue in their bodies. Key Findings Researchers tested 30 teenagers, some with IR and others without it, using a glucose test and MRI scans. They found: Teenagers with IR had a harder time controlling […] ➡️➡️➡️

Vitamin D₃ for Tic Disorders in Children Background Vitamin D₃ might help reduce tic symptoms in children with chronic tic disorders (CTDs). This study looked at how different doses of vitamin D₃ affect tic severity and vitamin D levels in kids diagnosed with CTDs. Study Overview In the study, 83 children aged 4 to 15 […] ➡️➡️➡️

Comparison of Ticagrelor and Clopidogrel This study looked at how well Ticagrelor and Clopidogrel work for patients with coronary heart disease and unstable angina. The goal was to understand their effects on heart health and inflammation. Key Findings The Ticagrelor group had fewer angina attacks compared to the Clopidogrel group. Patients taking Ticagrelor experienced shorter […] ➡️➡️➡️

Background Chronic Plantar Fasciitis (CPF) is a condition that causes persistent foot pain and is often linked with anxiety and fear of movement. An approach called Pain Neuroscience Education (PNE) has shown potential in helping with these mental aspects, but there hasn’t been enough strong evidence on how well it works when combined with physiotherapy […] ➡️➡️➡️

Psychological Support for Cancer Patients This study focused on helping cancer patients who struggle with adjustment disorders through a special psychological program. Here’s what we found: Study Overview We looked at 59 cancer patients, dividing them into two groups: one received the psychological support program, and the other did not. The program included: Psychoeducation: 1-4 […] ➡️➡️➡️

Understanding Egg Allergy Prevention in Infants Key Findings from Recent Research Egg allergy (EA) is a common issue among children, alongside cow’s milk allergy and atopic dermatitis. This study highlights the benefits of introducing baked eggs into an infant’s diet early on. By starting baked egg consumption between 4 to 6 months of age and […] ➡️➡️➡️