Clinical trials

Understanding the Study on Cognitive Training and Postoperative Delirium Objective This study aimed to find out if cognitive training (CT) can help reduce postoperative delirium (POD) in older patients who had total hip and knee surgeries. Methods The clinical trial took place from February 18 to July 10, 2023. It included patients aged 60 to […] ➡️➡️➡️

MoKaRi Study Overview The MoKaRi study focuses on improving heart and metabolic health through diet. It examines how two different eating plans can reduce risks linked to heart disease. Study Details In this 20-week study, 65 participants with high levels of bad cholesterol (LDL-C) were involved. They were not taking any cholesterol-lowering medications. Each participant […] ➡️➡️➡️

Summary of the HOMAGE Trial Findings The HOMAGE trial aimed to understand how diabetes (DM) and coronary artery disease (CAD) affect heart health and how the medication spironolactone can help. The study included 495 participants, mostly older adults, and looked at heart function and specific blood markers over 9 months. Key Findings Participants with diabetes, […] ➡️➡️➡️

Background Pruritus, or itching, is a common skin issue that can be very uncomfortable. It can occur with various skin conditions and other health problems. Aim of the Study This study aimed to compare the effectiveness of three treatments for uremic pruritus: gabapentin, narrowband UVB therapy, and a combination of both. Methods The study involved […] ➡️➡️➡️

Background Chronic heart failure (CHF) can greatly reduce a patient’s quality of life and is costly for healthcare systems. This study looked at how personalized nutritional support from a specialized nursing team can help elderly patients with CHF. Study Overview The study involved 102 elderly patients with CHF who were hospitalized. They were divided into […] ➡️➡️➡️

Objective This study aimed to see how ultrasound-guided nerve blocks using Ropivacaine, with or without additional medications, affect pain relief and recovery in patients having thyroid cancer surgery. Methods 140 patients were divided into four groups for the surgery: Group C: General anesthesia only Group R: General anesthesia + Ropivacaine Group R1: General anesthesia + […] ➡️➡️➡️

Study Overview This study published in BMC Psychiatry explores how two techniques can help improve memory in people with schizophrenia. The techniques are called transcranial direct current stimulation (tDCS) and retrieval practice. Research Purpose The goal was to see if using tDCS, which targets a specific area of the brain, combined with retrieval practice can […] ➡️➡️➡️

Background After deep brain stimulation (DBS) for Parkinson’s disease (PD), changing medication doses may affect vision. However, no studies have specifically looked at this issue. Objectives This study aimed to compare the impact of reducing medication doses (levodopa-equivalent daily dose, or LEDD) on vision in PD patients after DBS. Methods In this clinical trial, 208 […] ➡️➡️➡️

Background Mood and anxiety disorders are common mental health issues. Research shows that using measurement-based care can help improve treatment outcomes by monitoring symptoms and guiding clinical decisions. An innovative approach is to include digital information from patients’ online activities, such as social media, to enhance this care. Both mental health professionals and patients are […] ➡️➡️➡️

“`html Understanding AI in Medical Consultations The use of artificial intelligence (AI) in healthcare aims to enhance diagnosis and consultation. However, it’s important to evaluate how this technology affects patients’ experiences and trust. Study Goals This study examines whether AI, or AI combined with human input, can effectively replace human doctors in diagnosis, focusing on: […] ➡️➡️➡️

“`html Improving Access to Hereditary Cancer Risk Assessments Current methods to enhance access to hereditary cancer risk assessments in primary care are insufficient. This study explores two strategies to identify patients with cancer histories and offer genetic testing. Study Overview The EDGE clinical trial involved 12 clinics across Montana, Wyoming, and Washington, engaging a total […] ➡️➡️➡️

Background Acne vulgaris is a common skin condition affecting up to 80% of people aged 11 to 30. It can lead to issues like redness, dark spots, and scarring, which negatively impact quality of life. Topical treatments are commonly used, and sticking to the treatment plan is crucial for success. Aims of the Study This […] ➡️➡️➡️

Background Research shows that screening can encourage people to change their behavior. Low physical activity (PA) is a risk factor for lung cancer that can be changed. This study looks at how safe and practical an 8-week exercise program is for people involved in lung cancer screening. Methods Participants without lung cancer from an Australian […] ➡️➡️➡️

Background Lacrimal irrigation is an important skill for diagnosing and treating eye conditions related to tear drainage. This study looks at two different techniques for lacrimal irrigation and introduces a new self-training model to help new ophthalmology residents learn these skills better. Methods In this study, 92 ophthalmology residents were divided into two groups. Both […] ➡️➡️➡️

“`html Background Diabetic polyneuropathy is a common condition affecting people with diabetes, but there are few proven treatments available. Current options include managing pain, using alpha-lipoic acid, and antidepressants. Some physical therapies, like electrical stimulation and heated stone therapy, have been suggested but lack strong evidence. Study Overview A study was conducted with 68 diabetic […] ➡️➡️➡️

Overview of the Study This study focused on cancer-related fatigue (CRF), a common and troubling issue for cancer patients. Researchers wanted to see if a treatment called 3.95 μm infrared moxibustion could help reduce this fatigue. Study Details A total of 65 cancer patients with CRF participated in a randomized controlled trial. The patients were […] ➡️➡️➡️

Clinical Trial Overview The study published in Lancet Oncology explores the best timing for using nivolumab (a type of PD-1 inhibitor) alongside chemotherapy in patients with early triple-negative breast cancer. The goal was to see how two different schedules of administering nivolumab with carboplatin and paclitaxel (two chemotherapy drugs) would affect treatment outcomes. Study Details […] ➡️➡️➡️

Background Recent research shows that a treatment called stereotactic body radiotherapy (SBRT) can help men with a specific type of prostate cancer that has spread to a few other areas. This study looked at whether adding a short course of hormone therapy (ADT) to SBRT could help patients live longer without their cancer getting worse. […] ➡️➡️➡️

Cognitive Behavioral Therapy for Insomnia in Young Cancer Survivors Background: Many young people who have survived childhood cancer experience insomnia, which can lead to poor health and a lower quality of life. Unfortunately, many do not receive the help they need. An online program called iSleep youth offers cognitive behavioral therapy specifically for insomnia. Study […] ➡️➡️➡️

Overview of Computerized Cognitive Training Computerized cognitive training (cCT) is a treatment that helps people practice mental tasks using a computer. It’s a non-invasive approach, meaning it doesn’t require surgery or other invasive procedures. Unlike traditional face-to-face training, which can be expensive and have long waiting times, mobile cCT is more accessible and flexible for […] ➡️➡️➡️