Clinical trials

Objective: Vonoprazan is a new medication that helps treat Helicobacter pylori infections effectively. This study compares a 14-day treatment with vonoprazan and amoxicillin against personalized therapy based on drug sensitivity. Methods: In this study, 240 adults who did not respond to previous H. pylori treatments were randomly assigned to either the vonoprazan-amoxicillin treatment or the […] ➡️➡️➡️

Study Overview: This research focused on how effective pronase is in finding early cancer and improving visibility during gastroscopy in China. Study Details: 1450 patients were part of a program for early detection and treatment of upper gastrointestinal cancer. Patients were divided into two groups: one group received pronase and dimethicone, while the other group […] ➡️➡️➡️

Background: Using less or no opioids during anesthesia can help reduce pain after surgery. However, it’s not clear how different methods affect patients who are more sensitive to pain, especially during laparoscopic cholecystectomy (gallbladder surgery). Study Overview: In this study, 173 patients scheduled for gallbladder surgery were divided into three groups: one with no opioids […] ➡️➡️➡️

Title: A Randomized Trial to Evaluate a Co-Created Health Promotion Intervention for Immigrants with Type 2 Diabetes Introduction: Engaging end users can help overcome barriers to effective health promotion for type 2 diabetes. The DIABETHIC project, funded by the European Union and the Italian Ministry of Health, includes a multicenter randomized controlled trial (RCT) to […] ➡️➡️➡️

Study Overview: This research, published in the Australasian Journal on Ageing, examines how integrating artificial intelligence (AI) and virtual reality (VR) into art therapy can improve cognitive function and mental health in older adults with mild cognitive impairment. Research Methods: In a randomized controlled trial, 60 older individuals with mild cognitive impairment were divided into […] ➡️➡️➡️

Title: The Role of Long-Term Hair Steroids as Biomarkers in PTSD Background: Dysregulation of steroid hormones is often linked to the development of posttraumatic stress disorder (PTSD). However, applying these findings in clinical settings to assess symptoms and treatment effectiveness is challenging. There is a lack of long-term data on steroid levels during treatment. Objective: […] ➡️➡️➡️

Title: Evaluation of Renal Blood Flow Estimation Using Rubidium-82 PET/CT Background: Various techniques exist for estimating renal blood flow (RBF), but they have not been widely adopted in clinical practice due to their limitations. Our previous research indicated that rubidium-82 (82Rb) positron emission tomography/computed tomography (PET/CT) is a promising method for assessing renal perfusion. This […] ➡️➡️➡️

Recent research published in the Archives of Dermatological Research explored the effectiveness of carboxytherapy in managing acne flare while patients are undergoing treatment with oral isotretinoin for moderate to severe acne vulgaris. Oral isotretinoin is widely used to treat acne and prevent associated scarring and psychological issues. However, one of its side effects is an […] ➡️➡️➡️

Title: Analysis of MiRNAs as Biomarkers for Nutritional Therapy in Type 2 Diabetes Remission Abstract: Background: Type 2 diabetes mellitus (T2DM) is a significant global health issue. Achieving remission from this disease is possible; however, effective biomarkers for selecting the most suitable diet are limited. This study aims to evaluate the role of microRNAs (miRNAs) […] ➡️➡️➡️

Clinical Trial Results for HPV Treatment in Women Living with HIV Overview of the Study We conducted a clinical trial to see which method works better for treating HPV in women living with HIV. We compared two approaches: 1. **HPV screen and treat**: All HPV-positive women received treatment. 2. **HPV screen, triage, and treat**: Only […] ➡️➡️➡️

Understanding Gynecomastia Treatment Options Study Overview This study looks at how effective two modern treatments for gynecomastia (enlarged breast tissue in men) are compared to traditional surgery. The treatments are endoscopic lipolysis and liposuction. Study Details A total of 140 men with gynecomastia participated in this study. They were divided into two groups: one group […] ➡️➡️➡️

Understanding Transcranial Direct Current Stimulation for ADHD What is the Study About? This study looks at a new treatment called transcranial direct current stimulation (tDCS) for children with attention-deficit/hyperactivity disorder (ADHD). tDCS might help improve brain function in kids with ADHD, but more research is needed to be sure it works well and is safe. […] ➡️➡️➡️

Nutrition Supplementation and Exercise for Knee Osteoarthritis Study Purpose This study looked at how well nutrition supplements (like glucosamine and chondroitin) and exercise work together to help people with knee osteoarthritis (OA) compared to just exercise alone. Study Details A total of 65 people aged 40-75 with knee OA took part in this study. They […] ➡️➡️➡️

Understanding the Safety of Imetelstat in Heart Health What is Imetelstat? Imetelstat is a new drug that targets telomerase, an enzyme linked to cancer. Researchers wanted to see if it affects heart health, especially the risk of heart rhythm problems. How Was the Study Conducted? The study included both laboratory tests and tests on animals […] ➡️➡️➡️

Understanding Clinical Trials for Breast Cancer Treatment What Was the Study About? This study looked at a specific group of women with a type of breast cancer called ductal carcinoma in situ (DCIS) that is positive for estrogen receptors (ER+). They were treated with a drug called letrozole for 6 months before surgery. The main […] ➡️➡️➡️

Understanding Clinical Trials for Businesses What Was the Study About? The study looked at how well a medicine called dexamethasone works when applied to the skin during a specific jaw surgery. The goal was to see if it helps reduce pain and problems with feeling in the mouth after the surgery. How Was the Study […] ➡️➡️➡️

Understanding Clinical Trials for ADHD Educational Programs What is the Study About? This study looked at a new educational program for adults recently diagnosed with ADHD. The program was created with help from patients, caregivers, and health workers. The goal was to see if the program was easy to use and if people liked it. […] ➡️➡️➡️

Understanding the ATLAS/NOA-29 Clinical Trial What is the ATLAS/NOA-29 Trial? The ATLAS/NOA-29 trial is a research study that compares two types of brain surgery for patients with a specific type of brain tumor called glioblastoma. The goal is to see which surgery helps patients live longer and have a better quality of life. Why is […] ➡️➡️➡️

Understanding Clinical Trials on Pain Relief Techniques What Was Studied? This study looked at two methods to relieve pain in the arms and hands: Stellate Ganglion Block (SGB) and Thoracic Paravertebral Block (TPVB). The goal was to see which method worked better. How Was the Study Done? Patients aged 19 to 85 with chronic arm […] ➡️➡️➡️

Understanding Recovery After General Anesthesia Background Recovering from general anesthesia can be tricky. Patients need to be awake enough to follow instructions and answer questions about their thinking skills. Current tests depend on how well patients can understand and speak. However, we haven’t looked closely at how anesthesia affects speech and language. This study introduces […] ➡️➡️➡️