Clinical trials

Understanding the Trial Results The trial compared two methods for colonoscopy: water-assisted colonoscopy (WAC) and conventional carbon dioxide insufflation colonoscopy (CC). It involved beginner endoscopists who had performed fewer than 150 procedures before. What Worked? WAC was found to be a safe and effective alternative to CC. Procedure times were similar for both methods. Patients […] ➡️➡️➡️

Trial Results Explained The study tested a treatment for stage-II periodontitis, which is a type of gum disease. It looked at three groups: First group: Received professional cleaning plus injectable platelet-rich fibrin (I-PRF) with vitamin C. Second group: Received professional cleaning plus I-PRF without vitamin C. Third group: Received only professional cleaning. Here’s what the […] ➡️➡️➡️

Understanding the Trial Results This study looked at how well sensorimotor training (SoMT) combined with core strength training (CST) can help adults with low back pain and scoliosis. Here’s what they found: What Worked? The combination of SoMT and CST may reduce low back pain significantly. Patients may also see improvements in their overall health […] ➡️➡️➡️

Understanding the Trial Results This research compares two types of treatments for adults with post-traumatic stress disorder (PTSD) who have experienced multiple traumatic events. The two treatments are: Spaced Trauma-Focused Treatment (S-TFT): This is the standard treatment, where patients attend weekly sessions. Massed Trauma-Focused Treatment (M-TFT): This involves more frequent sessions, potentially leading to faster […] ➡️➡️➡️

Understanding the ExtraCECI Trial Results The ExtraCECI trial aimed to improve the quality of life for people living with HIV/AIDS in Ghana. Here’s what the results mean for patients and clinics: What Worked? The ExtraCECI intervention helped improve the overall quality of life for participants compared to standard care. Healthcare professionals received training to provide […] ➡️➡️➡️

Understanding the Trial Results The trial looked at how well extended CT angiography works compared to standard CT angiography in finding blood clots in the heart and aorta in patients who had a stroke or a mini-stroke. Here’s what we found: What Worked: Extended CT angiography detected more cardioaortic thrombi (blood clots) than standard CT […] ➡️➡️➡️

Understanding the PRO-TECT Trial Results The PRO-TECT trial looked at how patients report their symptoms during cancer treatment. It offered two ways for patients to share their health updates: through the internet or by phone. This study aimed to see if using a phone option could help patients who might not have easy internet access. […] ➡️➡️➡️

Trial Results Explained The study compared two antiseptics used for cleaning central catheters in intensive care units: one with hypochlorous acid and the other with povidone-iodine. The results showed that: The group using hypochlorous acid had fewer infections related to their catheters compared to the group using povidone-iodine. Signs of infection at the catheter site […] ➡️➡️➡️

Study Overview This study looked at how pulmonary rehabilitation (PR) helps patients with COVID-19 who were in the intensive care unit (ICU) and after they left the hospital. We wanted to see if PR could improve breathing difficulties, daily activities, anxiety, depression, and overall quality of life. What Worked Pulmonary rehabilitation had positive effects on […] ➡️➡️➡️

Understanding the Trial Results What Worked? Both the generative AI and rules-based digital mental health interventions (DMHIs) provided similar user experiences. The generative AI was better at understanding and responding with empathy, achieving 98% accuracy compared to 69% for the rules-based version. No serious problems or harmful events occurred during the trial. Technical safeguards for […] ➡️➡️➡️

Understanding the Trial Results The trial tested an app designed to help doctors detect depression better in patients. It was conducted in Nepal and Nigeria, comparing traditional training with training using the app. What Worked? In Nepal, doctors using the app detected depression in 24% of patients after training, up from 0% before. In Nigeria, […] ➡️➡️➡️

Trial Results Explained The study tested a new 1% ibuprofen gel to see if it could help reduce sensitivity during in-office teeth whitening. Unfortunately, the results showed that the gel did not help with sensitivity or change the color of the teeth. What Worked: The gel did not affect the color change of the teeth. […] ➡️➡️➡️

Understanding the Trial Results The study looked at a treatment called intermittent theta-burst stimulation (iTBS) for patients who have unilateral neglect (UN) after a stroke. UN means that patients may ignore one side of their body or space. Here’s what the results showed: What Worked: Patients who received iTBS showed significant improvements in tasks that […] ➡️➡️➡️

Trial Results Explained The study looked at three treatment methods for patients with permanent teeth that had decay and needed direct pulp capping (DPC). The methods were: Biodentine alone Er: YAG laser followed by Biodentine Er: YAG laser alone The main finding was that using the Er: YAG laser with Biodentine led to better results. […] ➡️➡️➡️

Understanding the Study Results This study focused on improving how doctors in Cuba detect dementia, especially in low- and middle-income countries (LMICs). Here’s what we found: What Worked: Doctors who received special training felt more confident and were better at diagnosing dementia. What Didn’t Work: The study did not address all barriers to diagnosis, such […] ➡️➡️➡️

Understanding the Trial Results The study looked at how a probiotic called Limosilactobacillus reuteri, when combined with non-surgical periodontal therapy, affects patients with stage III-IV periodontitis. Here’s what they found: What Worked: Both the test group (with probiotics) and the control group (without probiotics) showed improvement in periodontal health. The test group had a notable […] ➡️➡️➡️

Understanding the Trial Results The study looked at whether adding moxifloxacin, an antibiotic, during eye injections can prevent infections after treatment for conditions like cystoid macular edema and macular neovascularization. Here’s what they found: What Worked: Using moxifloxacin did not lead to any cases of infection (endophthalmitis) in the group that received it, while there […] ➡️➡️➡️