Home-Use Agents for Dentin Hypersensitivity Treatment
Study Overview
This study evaluated how effective home-use desensitizing agents are over an 8-week period. Different measurement methods were used to compare their effectiveness.
Research Details
A clinical trial involved 180 participants aged 18 to 70 with diagnosed dentin hypersensitivity (DH). Out of these, 164 individuals met the criteria and were divided into five groups using:
- Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP)
- Arginine
- Novamin
- Propolis
- Potassium nitrate
Additionally, there was a control group using standard fluoride toothpaste. The effectiveness was measured at weeks 4 and 8 by an independent examiner using different scales.
Key Findings
All test groups showed significant improvement in DH by weeks 4 and 8 compared to their starting points, as measured by:
- Dentine Hypersensitivity Experience Questionnaire-15 (DHEQ-15)
- Visual Analog Scale (VAS)
- Schiff Sensitivity Scale (SSS)
The control group only showed significant improvement in VAS and SSS by week 8. Notably, the CPP-ACP group had the best results by week 8, with the following scores:
- DHEQ-15: 56.68 ± 17.87
- VAS: 6.52 ± 1.48
- SSS: 2.32 ± 0.56
Conclusions
CPP-ACP was the most effective in reducing DH symptoms, suggesting it is a strong option for home use.
Clinical Importance
Home-use desensitizing agents can effectively treat DH, improving patients’ daily lives, especially for those unable to seek clinical care. They also provide relief before any necessary clinical procedures.
Trial Registration
ClinicalTrials.gov Identifier: NCT06216262
Learn More
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