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Artificial Intelligence Solutions in Healthcare
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Quality of life, pain and use of analgesic, anxiolytic and antidepressant medication, in people living in care homes
Quality of Life and Medication Use in Care Home Residents Study Overview People living in care homes often experience pain, anxiety, and depression. This study aimed to investigate the relationship between medication use and the severity of pain, anxiety, and depression, as well as the impact on the quality of life in care home residents.…
Adverse effects, Clinical outcomes, Clinical research, Clinical study, Control arm, Data collection, Double-blind, Drug trial, Efficacy, Patient consent, Patient enrollment, Placebo, Randomization, Regulatory approval, Safety profile, Study design, Study protocol, Treatment group, Trial monitoring, Trial phase -
Impact of a multimodal effort re-education programme on functionality, physical performance, and functional capacity in cancer patients with dyspnoea: a randomised experimental study
Impact of a Multimodal Effort Re-education Programme for Cancer Patients with Dyspnoea Study Overview A study was conducted to test the effectiveness of a re-education programme in improving respiratory symptoms and functionality in cancer patients with dyspnoea. Methodology The study was a randomised experimental trial involving cancer patients from a specific hospital in Spain. Two…
Adverse effects, Clinical outcomes, Clinical research, Clinical study, Control arm, Data collection, Double-blind, Drug trial, Efficacy, Patient consent, Patient enrollment, Placebo, Randomization, Regulatory approval, Safety profile, Study design, Study protocol, Treatment group, Trial monitoring, Trial phase -
Clinical breakage, slippage and acceptability of two commercial ultra-thin polyurethane male condoms compared to a commercial thin latex condom: a randomised, masked, 3 way crossover, multi centre controlled study (SAGCS 2)
Study Title: Clinical Trial on Ultra-Thin Polyurethane Condoms Published in Reprod Health, 2024 Sep 4;21(1):128 Objective: Evaluate breakage, slippage, and acceptability of two ultra-thin polyurethane condoms against a thin latex condom in a randomized, crossover, non-inferiority study. Design: The study followed ISO 29943-1: 2017 and FDA guidelines, conducted at two Essential Access Health centers in…
Adverse effects, Clinical outcomes, Clinical research, Clinical study, Control arm, Data collection, Double-blind, Drug trial, Efficacy, Patient consent, Patient enrollment, Placebo, Randomization, Regulatory approval, Safety profile, Study design, Study protocol, Treatment group, Trial monitoring, Trial phase -
Randomized study for a novel elbow joint fixation device on postoperative complications in patients undergoing percutaneous coronary diagnostic or therapeutic procedures through the brachial artery
Study Results: Novel Elbow Joint Fixation Device Reducing Complications in Brachial Artery Procedures Patients undergoing percutaneous coronary diagnostic or therapeutic procedures through the brachial artery face a higher risk of vascular complications. A randomized study investigated the use of a 3D-printed elbow joint fixation device to reduce postoperative complications in these patients. Results showed that…
Adverse effects, Clinical outcomes, Clinical research, Clinical study, Control arm, Data collection, Double-blind, Drug trial, Efficacy, Patient consent, Patient enrollment, Placebo, Randomization, Regulatory approval, Safety profile, Study design, Study protocol, Treatment group, Trial monitoring, Trial phase -
Comparison of established and preliminarily proposed ASAS MRI working group cut-offs for inflammatory MRI lesions in the sacroiliac joints in radiographic and non-radiographic axial spondyloarthritis
Comparison of MRI Cut-offs for Inflammatory Lesions in Axial Spondyloarthritis Background A study compared the established and newly proposed MRI cut-offs for inflammatory lesions in the sacroiliac joints in patients with axial spondyloarthritis. The new cut-offs were preliminarily proposed in 2021. Methods The study used MRI scans from 657 patients to categorize them as MRI-positive…
Adverse effects, Clinical outcomes, Clinical research, Clinical study, Control arm, Data collection, Double-blind, Drug trial, Efficacy, Patient consent, Patient enrollment, Placebo, Randomization, Regulatory approval, Safety profile, Study design, Study protocol, Treatment group, Trial monitoring, Trial phase -
A 2.6% Benzoyl Peroxide AV Cleanser Specifically Designed for Sensitive Skin Offers Good Efficacy and Tolerability
Study Highlights: 2.6% Benzoyl Peroxide AV Cleanser for Sensitive Skin Effective and Well-Tolerated Treatment for Acne Vulgaris A clinical study evaluated the efficacy and safety of a 2.6% Benzoyl Peroxide (BPO) cleanser designed for sensitive skin in treating mild-to-moderate acne vulgaris (AV). The results showed a significant reduction in AV lesions as early as one…
Adverse effects, Clinical outcomes, Clinical research, Clinical study, Control arm, Data collection, Double-blind, Drug trial, Efficacy, Patient consent, Patient enrollment, Placebo, Randomization, Regulatory approval, Safety profile, Study design, Study protocol, Treatment group, Trial monitoring, Trial phase -
Evaluation of dentoalveolar changes following maxillary incisor intrusion with one vs two anterior miniscrews in subjects with gummy smile: a randomized clinical trial
Evaluation of Dentoalveolar Changes in Gummy Smile Subjects Comparison of One vs Two Anterior Miniscrews for Maxillary Incisor Intrusion Objective: To assess dentoalveolar changes after maxillary incisor intrusion with one or two anterior miniscrews in subjects with gummy smile and deep bite. Materials and Methods: Forty-three subjects were divided into two groups: group I with…
Adverse effects, Clinical outcomes, Clinical research, Clinical study, Control arm, Data collection, Double-blind, Drug trial, Efficacy, Patient consent, Patient enrollment, Placebo, Randomization, Regulatory approval, Safety profile, Study design, Study protocol, Treatment group, Trial monitoring, Trial phase -
A Randomized Controlled Trial to Determine the Impact of Resistance Training versus Aerobic Training on the Management of FGF-21 and Related Physiological Variables in Obese Men with Type 2 Diabetes Mellitus
A Randomized Controlled Trial to Determine the Impact of Resistance Training versus Aerobic Training on the Management of FGF-21 and Related Physiological Variables in Obese Men with Type 2 Diabetes Mellitus Key Findings: Fibroblast growth factor 21 (FGF-21) is a potential therapeutic target for insulin resistance in type 2 diabetes. This study compared the effects…
Adverse effects, Clinical outcomes, Clinical research, Clinical study, Control arm, Data collection, Double-blind, Drug trial, Efficacy, Patient consent, Patient enrollment, Placebo, Randomization, Regulatory approval, Safety profile, Study design, Study protocol, Treatment group, Trial monitoring, Trial phase -
Time-restricted eating with or without a low-carbohydrate diet improved myocardial status and thyroid function in individuals with metabolic syndrome: secondary analysis of a randomized clinical trial
Time-restricted eating and low-carbohydrate diet improve heart and thyroid health in metabolic syndrome Summary Researchers found that time-restricted eating (TRE) and low-carbohydrate diet (LCD) can significantly improve heart and thyroid function in people with metabolic syndrome (MetS). The study involved 169 MetS patients, who were randomly assigned to the LCD group, the 8-hour TRE group,…
Adverse effects, Clinical outcomes, Clinical research, Clinical study, Control arm, Data collection, Double-blind, Drug trial, Efficacy, Patient consent, Patient enrollment, Placebo, Randomization, Regulatory approval, Safety profile, Study design, Study protocol, Treatment group, Trial monitoring, Trial phase -
Effects of fructan and gluten on gut microbiota in individuals with self-reported non-celiac gluten/wheat sensitivity-a randomised controlled crossover trial
Effects of Fructan and Gluten on Gut Microbiota in Non-Celiac Gluten/Wheat Sensitivity Practical Solutions and Value Highlights Individuals with non-celiac gluten/wheat sensitivity (NCGWS) often experience improvement in gastrointestinal symptoms with a gluten-free diet. This study aimed to investigate the effects of fructo-oligosaccharides (FOS) and gluten on gut microbiota and related factors in NCGWS patients. The…
Adverse effects, Clinical outcomes, Clinical research, Clinical study, Control arm, Data collection, Double-blind, Drug trial, Efficacy, Patient consent, Patient enrollment, Placebo, Randomization, Regulatory approval, Safety profile, Study design, Study protocol, Treatment group, Trial monitoring, Trial phase