Clinical Trials

Background Prostate cancer (PC) is common and can be overwhelming for patients. Choosing the right treatment, like surgery or radiation, is tough. Many patients look for support from others who have been through similar experiences. Online support groups (OSGs) have gained importance, especially during the COVID-19 pandemic. Study Objective This study explores how patients with […] ➡️➡️➡️

“`html Objective The goal of this study was to see how well an automated digital health program could lower the risk of developing Alzheimer’s disease compared to a control group that did not receive specific treatment. Background Over 300 million people globally may have brain changes that lead to Alzheimer’s disease long before they show […] ➡️➡️➡️

“`html Impact of Lemborexant on Daytime Sleepiness in Patients with Insomnia and Mild Sleep Apnea Objective This study aimed to see how lemborexant, a medication for insomnia, affects morning alertness in adults with both insomnia and mild obstructive sleep apnea (COMISA). Background COMISA can lead to daytime sleepiness and cognitive problems. Some sleep medications can […] ➡️➡️➡️

Understanding the Myasthenia Gravis Study Results Objective This study aimed to understand how well the Myasthenia Gravis (MG) Symptoms Patient-Reported Outcome (PRO) scale relates to other measures of daily living and muscle strength in patients with MG. We used data from a clinical trial called MycarinG. Background The MG Symptoms PRO is a new tool […] ➡️➡️➡️

Study Overview The INFRONT-3 study is a significant clinical trial that looks at a new treatment called latozinemab for frontotemporal dementia (FTD) caused by a specific gene mutation. This trial aims to understand how effective and safe latozinemab is for patients. Key Findings A total of 119 participants joined the study, with an average age […] ➡️➡️➡️

Objective We aimed to find out what factors can predict cognitive decline in older adults who are currently cognitively healthy over a 5-year period. Background Alzheimer’s disease varies greatly among individuals, making it challenging to design clinical trials and select the right participants. Understanding how to identify more similar groups can help improve trial outcomes. […] ➡️➡️➡️

Objective The goal of this study was to evaluate the safety of bemdaneprocel and its effects on health outcomes for people with Parkinson’s disease (PD) over a period of 24 months following transplantation. Background Bemdaneprocel is a new treatment being tested for Parkinson’s disease. It uses special cells derived from human embryonic stem cells. Previous […] ➡️➡️➡️

Objective The goal of this study was to see how ampreloxetine (a medication taken by mouth at 10 mg/day) affects supine hypertension, which is high blood pressure when lying down. This was measured using ambulatory blood pressure monitoring. Background Patients with certain neurological conditions often experience both low blood pressure when standing (neurogenic orthostatic hypotension […] ➡️➡️➡️

Research on Radial Artery Occlusion Prevention Background Radial artery occlusion (RAO) can occur after coronary procedures. This study explores how different access points and anticoagulation methods can help prevent RAO. Aims of the Study The study aimed to examine the effectiveness and safety of various radial access sites and the use of anticoagulation during coronary […] ➡️➡️➡️

Background Low-dose chest CT scans are now commonly used, leading to more patients being diagnosed with subsolid nodules (SNs). This study looks at how effective radio-frequency ablation (RFA) is for treating patients with pulmonary ground glass nodules (GGNs) and how it affects lung function. Study Overview We studied 100 patients diagnosed with pulmonary GGN between […] ➡️➡️➡️

Study Overview This study compared the effectiveness and safety of two types of anesthesia: liposomal bupivacaine (Lip-BPVC) and standard bupivacaine (BPVC). The focus was on patients undergoing heart surgery called coronary artery bypass grafting (CABG). Study Method A total of 82 adult patients were divided into two groups: one received Lip-BPVC and the other received […] ➡️➡️➡️

Clinical Trial Results for Xinbao Pill in Microvascular Angina Overview Coronary microvascular dysfunction is a growing concern, but effective treatments are still lacking. This study examined the effectiveness of the Xinbao pill for patients suffering from microvascular angina (MVA). Study Details A total of 200 patients with MVA were enrolled in this study between January […] ➡️➡️➡️

Objective This study aimed to find out how effective a special type of endoscopy called magnifying endoscopy with narrow-band imaging (ME-NBI) is when combined with better nursing care in diagnosing early gastric cancer. Methods Patients who had a painless gastroscopy between January 1, 2021, and December 31, 2021, were randomly chosen for this study. They […] ➡️➡️➡️

Whole-Body Cryotherapy: Pain Relief Study Background Whole-body cryotherapy (WBC) involves exposing the body to very cold temperatures. It is commonly used to help reduce pain, but not much research has been done on how it works. This study looks at whether spending 3 minutes in a cryochamber can reduce pain sensitivity. Methods In this study, […] ➡️➡️➡️

Background Hypertension, or high blood pressure, is a significant health issue affecting many people. Even though there are treatments available, many individuals do not achieve the desired control over their blood pressure. Digital health tools can help improve how well these treatments work. One such tool is liebria, an online program that people can access […] ➡️➡️➡️

Aim of the Study The study aimed to compare the effectiveness and safety of two treatments for non-segmental facial vitiligo: microneedling with tacrolimus 0.03% ointment and microneedling with phenytoin 2% cream. Materials and Methods This study involved 40 patients with non-segmental facial vitiligo. They were split into two groups of 20. One group received microneedling […] ➡️➡️➡️

Purpose Patients with diffuse large B-cell lymphoma (DLBCL) in low-resource areas often have worse outcomes than those in wealthier regions. Rituximab, a medication that helps fight this cancer, can improve survival rates when combined with chemotherapy. However, its use is limited in low-resource countries due to a lack of infusion centers. Subcutaneous rituximab (sqR) could […] ➡️➡️➡️

Understanding the Telehealth Intervention for Stroke Recovery Low physical activity is a common issue for people who have had a stroke. This can lead to further health problems. Some studies suggest that changing behaviors can help increase physical activity, but there are challenges, such as needing home visits or internet access. A simple and cost-effective […] ➡️➡️➡️

Aim of the Study The study aimed to compare the results of two different treatments for patients with peri-implantitis, a condition affecting dental implants. It looked at non-surgical treatment followed by either reconstructive therapy or supportive care without further surgery. Study Overview This clinical trial involved 36 patients diagnosed with peri-implantitis and had specific bone […] ➡️➡️➡️

HIV Testing and Self-Testing Programs HIV testing is crucial for preventing the spread of the virus, especially among at-risk groups like gay and bisexual men. Self-testing for HIV (HIVST) can help people get tested more often and find out their status earlier. However, we need to understand what happens to testing habits after these self-testing […] ➡️➡️➡️