Clinical Trials

Background Wearable transdermal alcohol sensors (TAS) can continuously monitor alcohol consumption by detecting sweat on the skin. This technology could help alcohol treatment services keep track of users during their recovery process. Objective The goal of this study was to see if using a TAS is practical for people in alcohol treatment, both with and […] ➡️➡️➡️

PURPOSE This study aimed to evaluate how effective and safe a treatment called hyaluronidase-facilitated subcutaneous immunoglobulin (fSCIG) 10% is for children in the U.S. with primary immunodeficiency diseases (PIDDs). METHODS The research involved 44 children aged 2 to under 16, who had been receiving immunoglobulin G (IgG) continuously for at least 3 months before the […] ➡️➡️➡️

Study Overview This study looked at how two methods—diaphragm breathing relaxation training and cognitive-behavioral therapy (CBT)—can improve sleep quality in older adults suffering from insomnia. Study Design The research involved 99 older patients, divided into three groups: two treatment groups (33 participants each) and one control group (33 participants). The treatments lasted four weeks: CBT-I: […] ➡️➡️➡️

Study Overview This study aimed to explore how coconut oil affects oral bacteria and inflammation in patients with gum disease (periodontitis). Researchers used advanced sequencing methods to analyze changes in harmful bacteria and measure inflammatory markers, assessing coconut oil’s potential as a natural addition to standard gum treatment. Study Design A triple-blind clinical trial involved […] ➡️➡️➡️

Study Overview This study explored how pelvic proprioceptive neuromuscular facilitation (PNF) techniques can help patients with sacroiliac joint dysfunction (SIJD), a common cause of low back pain that is often overlooked. Study Details The research involved 40 patients aged 18 to 40 who had been experiencing pain for at least 4 weeks. They were divided […] ➡️➡️➡️

Background Chronic pelvic pain is a significant issue for many women, affecting their quality of life. The Neuro Emotional Technique (NET) is a new approach that aims to help reduce emotional distress and pain associated with this condition. Study Overview This study involved 26 women with chronic pelvic pain. They were divided into two groups: […] ➡️➡️➡️

Impact of Social Marketing on Pap Smear Test Uptake Background: This study aimed to see how social marketing can help increase the number of women getting Pap smear tests, which are important for detecting cervical cancer early. Study Overview The research took place from June 5 to August 6, 2023, in Qazvin City. It involved […] ➡️➡️➡️

Background Previous studies have shown differences in healthcare for people living with dementia or mild cognitive impairment based on whether they live in urban or rural areas. However, it’s unclear if these differences exist for those living in shared-housing arrangements. Methods In a study called the “DemWG study,” we recruited 341 participants from 97 shared-housing […] ➡️➡️➡️

Introduction Postoperative delirium affects up to 40% of older patients after surgery. This condition can lead to longer hospital stays, lasting cognitive issues, and higher chances of death within a year after surgery. Sleep problems after surgery may increase the risk of delirium. However, there are few studies on medications that can improve sleep and […] ➡️➡️➡️

Study Overview This study looked at how group fitness classes affect heart and blood vessel health in young and middle-aged adults. Specifically, it focused on arterial stiffness and heart rate variability, which are important for cardiovascular health. Key Findings 1. Impact on Blood Pressure: Middle-aged adults experienced lower blood pressure after participating in various exercise […] ➡️➡️➡️

Vitamin K2 and Nocturnal Leg Cramps Research shows that Vitamin K2 can help reduce the frequency of leg cramps at night, especially in elderly patients. This finding opens doors for better healthcare solutions. Measurable Outcomes Clinics and patients should aim for clear goals. One goal is to decrease the number of leg cramps experienced by […] ➡️➡️➡️

Clinical Trial Overview This study focused on older patients with acute myeloid leukemia (AML), who often do not respond well to standard treatments. Researchers explored a new treatment combining chidamide, CAG, and venetoclax-azacitidine, known as CACAG-VEN. Study Details Forty patients aged 60 and above participated in this phase 2 trial. They received a specific combination […] ➡️➡️➡️

Introduction Primary headaches are a major issue for children and teenagers, showing the need for effective treatments that do not rely on medications. One promising method is called transcutaneous auricular vagus nerve stimulation (taVNS), which is a non-invasive treatment that has worked well for adults with headaches and has been deemed safe for adolescents with […] ➡️➡️➡️

Study Overview This study aimed to understand how different advice on drinking fluids affects the occurrence of headaches after a lumbar puncture, a common medical procedure. Study Design We conducted a trial in seven hospitals in France with patients who needed a lumbar puncture. Patients were randomly divided into two groups: FREE-FLUID Group: No specific […] ➡️➡️➡️

Background Functional dizziness is a common issue that often comes with other mental health problems like depression and anxiety. These conditions can make it hard for patients to manage their dizziness, possibly due to imbalances in the autonomic nervous system. Our study looked at whether heart rate variability (HRV) biofeedback could help improve this condition. […] ➡️➡️➡️

Objective We studied how tumor cells behave in Chinese patients with mantle-cell lymphoma (MCL) and found they may grow faster than in Western patients. To address this, we designed a clinical trial to test a new treatment combining R-DA-EDOCH immunochemotherapy and R-DHAP therapy in young patients with newly diagnosed MCL. Methods We included 55 patients […] ➡️➡️➡️

“`html Overview of the Study This study focuses on advanced gastric cancer (GC), a common and serious cancer with a poor outlook. Current treatments, like paclitaxel and nab-paclitaxel, are often not very effective. Researchers are exploring new combinations of treatments to improve patient outcomes. What is Being Tested? The study is testing a new combination […] ➡️➡️➡️

Background Malnutrition is a common problem in intensive care units (ICUs), often caused by interruptions in enteral nutrition (EN). Aim of the Study This study looked at how often EN interruptions happen, why they occur, and how they affect patient nutrition in the ICU. Study Design This analysis involved 1,331 ICU patients who were receiving […] ➡️➡️➡️

Background Anemia is a serious problem caused by malaria, and diagnosing it correctly is essential for proper treatment. Traditional laboratory tests to measure hemoglobin (Hb) levels, such as the Coulter Counter and Quantitative Buffy Coat® (QBC®), can be expensive and are not always available in low-resource areas. The HemoCue® test is a more affordable option […] ➡️➡️➡️

Background Gastroenteritis is a leading cause of death in children worldwide, claiming around 3 million lives each year among those under 5 years old. Rotavirus is a significant cause of viral diarrhea in children aged 6 months to 2 years, leading to severe symptoms like watery diarrhea and vomiting. While supportive care and vaccines have […] ➡️➡️➡️