Affordable Web-Based Foot-Ankle Exercise Program for Diabetic Foot Care Key Findings: An affordable web-based foot-ankle exercise program, SOPeD, has proven effective in treating modifiable risk factors for ulcer prevention in individuals with diabetes-related peripheral neuropathy (DPN). The program effectively reduced foot pain, improved foot function, and demonstrated favorable cost-effectiveness. Practical Solutions and Value: The study…
Study Summary: Could TREM-1 be a Novel Marker in the Diagnosis of Fibromyalgia? Key Findings: Researchers investigated the potential role of TREM-1 in the context of fibromyalgia syndrome (FMS) and its association with disease activity. The study included 45 FMS patients and 46 healthy individuals as a control group. The findings revealed significantly elevated concentrations…
Enhancing treatment of lumbar disc herniation with Erxian decoction and auricular acupoint pressure: A randomized controlled trial Objective The study aimed to assess the clinical effectiveness of combining Erxian decoction with auricular acupoint pressure therapy in treating lumbar disc herniation (LDH). The goal was to provide evidence for integrating traditional Chinese medicine (TCM) rehabilitation techniques…
Kisspeptin Expression Levels in Patients with Placenta Previa: A Randomized Trial Medicine (Baltimore). 2024 Jul 12;103(28):e38866. doi: 10.1097/MD.0000000000038866. Background: This study aimed to investigate the impact of kisspeptin (KISS1) levels on the development of placenta previa for early pregnancy diagnosis. Methods: The study included 20 pregnant women diagnosed with placenta previa and 20 pregnant women…
Patient Satisfaction with Letter-Based Communication of LCS Pulmonary Nodule Results Objective To analyze patient satisfaction with letter-based communication of lung cancer screening (LCS) pulmonary nodule results. Study Design Prospective randomized controlled trial of LCS between May and December 2019. Methods All participants came from a prospective randomized controlled study on pulmonary nodule results in LCS…
Effect of empagliflozin on Myocardial Infarction in Patients with Type 2 Diabetes and Cardiovascular Disease Study Summary This study investigated the impact of empagliflozin, a drug used to treat type 2 diabetes, on the risk of experiencing heart attacks in patients with both type 2 diabetes and cardiovascular disease. The study followed 7020 participants for…
Study Title: A low molecular weight dextran sulphate, ILB, for the treatment of amyotrophic lateral sclerosis (ALS): An open-label, single-arm, single-centre, phase II trial Summary Amyotrophic lateral sclerosis (ALS) is a severe neurological condition with no cure. This study investigated the safety and tolerability of ILB® in ALS patients. The trial showed that long-term weekly…
Evaluating the impact of oral hygiene instruction and digital oral health education within cardiac rehabilitation clinics: A protocol for a novel, dual centre, parallel randomised controlled trial ABSTRACT Oral health is closely linked to cardiovascular health, and inflammatory gum diseases can have significant systemic implications. This study aims to assess the effectiveness of individualized oral…
Six-month Coenzyme Q10 Supplementation Improves Liver and Cardiovascular Function Study Overview A clinical trial assessed the effects of coenzyme-Q10 supplementation on patients with Metabolic-dysfunction Associated Steatotic Liver Disease (MASLD). Results After six months, patients receiving coenzyme-Q10 showed significant improvements in various measures, including reduced liver steatosis, improved endothelial and vascular function, and enhanced myocardial function.…
Effectiveness of personalized rehabilitation in adults suffering from persistent concussion symptoms as compared to usual care: a randomized control trial protocol ABSTRACT Symptoms reported by patients who sustain a concussion are non-specific. Clinicians can better manage patients by performing a standardized clinical exam to identify the underlying causes of symptoms. Aerobic exercise and multimodal rehabilitation…
Yorkshire Lung Screening Trial (YLST) Pathway Navigation Study A Protocol for a Nested Randomised Controlled Trial to Evaluate the Effect of a Pathway Navigation Intervention on Lung Cancer Screening Uptake BMJ Open. 2024 Jul 9;14(7):e084577. doi: 10.1136/bmjopen-2024-084577. Introduction: Lung cancer is a leading cause of cancer death worldwide. The UK National Screening Committee recommended a…
Multidimensional Screening and Intervention Program for Neurocognitive Disorder in Vascular and Multimorbid Outpatients: Study Protocol for a Randomized Clinical Trial Abstract The study aims to develop innovative strategies for individuals with dementia secondary to cerebrovascular or other medical diseases. It emphasizes the importance of physical and cognitive activities in protecting against cognitive decline. Methods The…
Study: Effectiveness of Additional HIV Self-Test Kits as an Incentive to Increase HIV Testing Key Findings: In a study conducted in Western Kenya, offering a second HIV self-test (HIVST) as an incentive within assisted partner services did not significantly impact HIV testing rates or first-time testing. However, those who opted for the second test reported…
Artificial Intelligence-Based Training for Pulmonary Nodule Diagnosis Published in BMC Medical Education, July 2024 Background: The study aimed to assess the effectiveness of an artificial intelligence (AI)-assisted diagnosis system in training junior radiology residents and medical imaging students in detecting and diagnosing pulmonary nodules. Methods: Participants were divided into three groups: two groups of medical…
Prevalence of Vitamin D Deficiency and the Effect of Vitamin D3 Supplementation on Response to Anti-Tuberculosis Therapy in Patients with Extrapulmonary Tuberculosis ABSTRACT We conducted a study to measure serum vitamin D levels in patients with extrapulmonary tuberculosis (EPTB) and to assess the impact of vitamin D3 supplementation on their treatment. In our study, we…
Study: Non-diabetes Status After IGT Diagnosis and Long-Term Risks Background The study aimed to clarify the association between years of non-diabetes status after diagnosis of impaired glucose tolerance (IGT) and the risk of long-term death and cardiovascular outcomes. Methods and Findings 540 individuals with IGT from the Da Qing Diabetes Prevention Study were included in…
Bone Pain and Survival Among Patients With Metastatic, Hormone-Sensitive Prostate Cancer: A Secondary Analysis of the SWOG-1216 Trial Summary: The study aimed to compare survival outcomes among patients with metastatic, hormone-sensitive prostate cancer (MHSPC) based on the presence or absence of baseline bone pain at diagnosis. Methodology: The analysis used patient-level data from the SWOG-1216…
Relaxation Intervention for Diabetic Foot Ulcer Healing Study Overview A pilot study was conducted to assess the feasibility and acceptability of a relaxation intervention for diabetic foot ulcer (DFU) healing. The study compared progressive muscle relaxation with guided imagery (experimental group) to a neutral guided imagery placebo (active control group) and a group that did…
Clinical Trial Results: Interactive Walkway for Fall-Risk Biomarkers in the Elderly Key Findings: Study compared zolpidem and suvorexant in elderly subjects to assess the sensitivity of the Interactive Walkway (IWW) in measuring walking adaptability and fall risk. Results indicated that zolpidem led to decreased performance in walking adaptability, Timed-Up-and-Go test, and body sway, while suvorexant…
Daratumumab in transplant-eligible patients with newly diagnosed multiple myeloma: final analysis of clinically relevant subgroups in GRIFFIN Blood Cancer J. 2024 Jul 8;14(1):107. doi: 10.1038/s41408-024-01088-6. The GRIFFIN study (NCT02874742) investigated daratumumab plus lenalidomide/bortezomib/dexamethasone (D-RVd) in newly diagnosed multiple myeloma (NDMM) patients who are eligible for transplant. The study’s final analysis focused on subgroups, including those…