Assessing Patient Perspectives and Health Equity in Digital Cancer Symptom Management Summary Researchers evaluated Symptom Care at Home (SCH), a digital system for managing cancer symptoms, to assess patient engagement, user satisfaction, and intervention benefits across different patient groups. The study aimed to reduce disparities in symptom care outcomes. Key Findings Participants using SCH reported…
Diagnostic Accuracy of AI-Based Symptom Checker and Web-Based Self-Referral Tool in Rheumatology Key Findings The study aimed to evaluate the diagnostic accuracy of a mobile artificial intelligence (AI)-based symptom checker (Ada) and a web-based self-referral tool (Rheport) in identifying inflammatory rheumatic diseases (IRDs). Results showed that both tools demonstrated overall diagnostic accuracies of 52% to…
Diagnostic Accuracy of Mental Health Screening Tools After Mild Traumatic Brain Injury JAMA Netw Open. 2024 Jul 1;7(7):e2424076. doi: 10.1001/jamanetworkopen.2024.24076. Importance: Mental health disorders are common after mild traumatic brain injury (mTBI) and can worsen postconcussive symptoms and disability. Detecting these disorders early can improve clinical outcomes, but the accuracy of mental health screening tools…
The Effect of Histopathologic Analysis and Tissue Cultures on Cellulitis Management Background In cases of cellulitis, it can be challenging to accurately diagnose due to the lack of a definitive diagnostic method, leading to potential misdiagnosis of other inflammatory disorders as cellulitis. Objective This study aimed to assess the usefulness of skin biopsy and tissue…
Effectiveness of Culturally Tailored HIV Intervention in Promoting PrEP Among Black Women Key Findings: In a randomized clinical trial, a culturally-tailored HIV intervention called E-WORTH significantly increased awareness of PrEP and willingness to use PrEP among Black women in community supervision programs in New York City. Practical Solutions: These findings highlight the need for more…
Study on Preoperative Nutrition for Cancer Surgery Patients Key Findings Comparing the effects of preoperative nutrition drink and overnight parenteral nutrition on muscle metabolism in patients undergoing major gastrointestinal cancer surgery. Results The study found that the preoperative nutrition drink had limited impact on muscle metabolism, particularly in glucose metabolism. On the other hand, overnight…
Sleep-Loss Related to Itch in Atopic Dermatitis: Assessing Content Validity and Psychometric Properties of a Patient-Reported Sleep-Loss Rating Scale Abstract Background: Sleep loss is a significant issue for people with atopic dermatitis (AD) due to itch. Addressing itch to improve sleep is a crucial aspect of AD treatment. Methods: Interviews were conducted with 21 adults…
Effects of a Web Application for Rotator Cuff-Related Shoulder Pain Protocol for an Open-Label Randomised Controlled Trial Introduction: Rotator cuff-related shoulder pain (RCRSP) is a common cause of shoulder pain. Exercise is the main treatment, but long-term adherence can be challenging. This study evaluates the effects of adding video animations to a traditional exercise programme.…
Comparison of Clinical Outcomes: Corneal Wavefront- vs. Topography-Guided LASIK Study Overview This study compared the outcomes of myopia correction using corneal-wavefront-guided (CWG) LASIK with AMARIS 1050S and corneal-topography-guided (CTG) LASIK with WaveLight EX500. Key Findings After 3 months postoperatively: Spherical and coma aberrations were significantly lower in the WaveLight group compared to the AMARIS group.…
Study Title: The TABANETOC Trial Objective: Evaluating the Anti-Neoplastic Effects of Tinzaparin in EOC Patients Background: Tinzaparin, a low-molecular weight heparin (LMWH), has demonstrated anti-neoplastic properties in animal models and in vitro studies of human cancer cell lines. Reduction in CA-125 levels during neoadjuvant chemotherapy (NACT) in patients with epithelial ovarian cancer (EOC) is associated…
Practical Solutions for Reducing Cerebral Infarction Recurrence Study Overview To reduce the risk of cerebral infarction recurrence after cerebrovascular intervention, a clinical trial was conducted on 202 patients. The treatment group received clopidogrel doublet augmented antiplatelet therapy, while the control group received aspirin mono-antiplatelet therapy. Both groups continued the treatment for 2 months. Key Findings…
Effects of External Neuromuscular Electrical Stimulation in Women with Urgency Urinary Incontinence: A Randomized Sham-Controlled Study Background and Purpose The study aimed to investigate the effects of external neuromuscular electrical stimulation (NMES) on urinary symptoms, pelvic floor muscle strength (PFMS), quality of life (QoL), sexual function, perception of subjective improvement (PSI), and satisfaction in urgency…
Eyesi Direct Ophthalmoscope Simulator: Enhancing Fundus Examination Training Introduction Medical undergraduates often lack proper training in using direct ophthalmoscopes, leading to a shortage of basic ophthalmological skills among general practitioners worldwide. This study investigates the effectiveness of the Eyesi Direct Ophthalmoscope Simulator (Eyesi) as a modern tool for fundus examination training. Methods Undergraduates were randomly…
ROSELLA: Phase 3 Clinical Trial for Ovarian Cancer Key Findings and Practical Solutions Ovarian cancer is often diagnosed late and becomes resistant to chemotherapy. The ROSELLA study aims to improve outcomes for women with platinum-resistant ovarian cancer by using relacorilant, a selective GR modulator, in combination with nab-paclitaxel. The study includes women with recurrent, platinum-resistant,…
Health-related Quality of Life in Patients with Metastatic Basal Cell Carcinoma Treated with Cemiplimab: Analysis of a Phase 2 Trial Key Findings: A phase 2 study of cemiplimab showed a 24.1% objective response rate in patients with metastatic basal cell carcinoma who were not suitable for continued hedgehog inhibitor therapy. The study focused on assessing…
Efficacy of Type A Botulinum Toxin Treatment for Androgenetic Alopecia Objective This study aimed to assess the efficacy of type A botulinum toxin treatment for androgenetic alopecia (AGA) using a combination of ultrasound and trichoscopy. Methods Ninety patients with AGA were selected and received injections of type A botulinum toxin or a control agent. Ultrasound…
Comparing the Effectiveness of Behavioral Activation in Group vs. Self-Help Format for Reducing Depression: A Clinical Trial Key Findings: Behavioral Activation Group Therapy (BAGT) showed significant improvement in depression, rumination, work, and social functioning post-treatment and at the 2-month follow-up. 68% of BAGT participants were responsive to treatment, and 31% achieved a high final performance…
HEV Vaccine and Fetal Loss in Rural Bangladesh Practical Solutions and Value Vaccination is an important way to control hepatitis E virus (HEV), which is a significant cause of maternal and perinatal mortality worldwide. However, a study of pregnant women in Bangladesh receiving the HEV vaccine HEV239 showed a potential link to fetal losses. This…
Sequence of Morphological Changes Preceding Atrophy in Intermediate AMD Using Deep Learning ABSTRACT PURPOSE: Investigating the sequence of morphological changes preceding outer plexiform layer (OPL) subsidence, a marker preceding geographic atrophy, in intermediate AMD (iAMD) using high-precision artificial intelligence (AI) quantifications on optical coherence tomography imaging. METHODS: In this longitudinal observational study, individuals with bilateral…
Targeted Vibratory Therapy for Chronic Low Back Pain in Older Patients Introduction As people age, their proprioceptive function declines, leading to issues such as falls, pain, and difficulty in daily activities. This clinical trial aimed to investigate the effectiveness of targeted vibratory therapy (TVT) in improving proprioceptive function and alleviating chronic low back pain (LBP)…