A Pilot Study on Qigong for Parkinson’s Disease Background Neuroinflammation is a key factor in the decline of neurons in people with Parkinson’s disease (PD). High levels of inflammatory markers, like IL-1β, IL-6, and TNF-α, are common in PD patients and relate to various non-motor symptoms. Qigong, a mind-body exercise, has been used to help…
Carrageenan and Insulin Resistance in Humans: A Clinical Trial Overview Study Background This study investigates the effects of carrageenan, a common food additive, on insulin resistance and inflammation in humans. While it is known to cause issues in animal studies, its impact on human health is not fully understood. Study Design A total of 20…
Effects of Canagliflozin on Patients with Type 2 Diabetes on Peritoneal Dialysis Study Overview Patients with type 2 diabetes (T2D) who are on dialysis face a higher risk of death due to heart and blood vessel issues. This study looks at how a medication called canagliflozin, which is used for T2D, affects heart health in…
A Phase II Study on Lenalidomide and Dexamethasone for Relapsed Multiple Myeloma Background Allogeneic stem cell transplant is currently the only potential cure for multiple myeloma (MM), but most patients will relapse. This study aimed to explore the effectiveness and safety of lenalidomide and dexamethasone (Len/Dex) followed by donor lymphocyte infusions (DLIs) in patients who…
Contrast-Enhanced Ultrasound vs. MRI for Liver Lesions Study Overview This study compares contrast-enhanced ultrasound (CEUS) with MRI for identifying focal nodular hyperplasia (FNH) and hepatocellular adenoma (HCA). MRI can be expensive and uncomfortable for patients, so we wanted to see if CEUS could provide similar results. Trial Details Approved by the institutional review board, this…
Effectiveness of the Community Paramedicine at Home (CP@home) Program Overview This study evaluates the CP@home program, which provides home visits by community paramedics to reduce emergency medical services (EMS) calls among frequent users in Ontario. Study Design The research was a 6-month randomized controlled trial, meaning participants were randomly assigned to either the CP@home program…
The Impact of Virtual Education on Women’s Breast Self-Examination Skills Study Overview This study explored how virtual education affects women’s ability to perform breast self-examinations (BSE), which is vital for early breast cancer detection. The goal was to see if online programs could improve knowledge, self-efficacy, and practical skills related to BSE. Methodology A total…
Efficacy and Safety of Mesenchymal Stem Cells in Treating Steroid-Refractory Acute Graft-Versus-Host Disease Background Many patients with acute graft-versus-host disease (aGVHD) do not respond well to corticosteroids. Mesenchymal stem cells (MSCs) may offer an effective second-line treatment for these patients, but more clinical studies are needed. Study Overview This study involved 78 patients with steroid-refractory…
Efficacy and Safety of Neurocognitive Adaptive Training for Depression A 12-Week Study Overview This study explored how Neurocognitive Adaptive Training for Depression (NCAT-D) works with selective serotonin reuptake inhibitors (SSRIs) to help patients with cognitive issues due to late-life depression (LLD). Study Details Conducted from May 5, 2021, to April 21, 2023, at Beijing Anding…
Randomized Controlled Trial of Cilostazol Addition for In-Stent Restenosis After Carotid Artery Stenting Background Restenosis, or narrowing of the arteries, after carotid artery stenting (CAS) can increase the risk of ischemic stroke. This study looked at whether adding cilostazol to treatment could reduce this risk. Methods In this trial, patients with carotid artery issues scheduled…
Study on Self-Management for People with Epilepsy Introduction Self-management tools can make epilepsy treatment more effective and accessible. However, we need more long-term data to prove their benefits. The Transtheoretical Model (TTM) helps tailor self-management to where individuals are in their behavioral change journey. This model aims to address specific needs, reduce information overload, minimize…
Development of a Mobile Health Support Program for Nigerian Women with Breast Cancer Background Breast cancer (BC) is a major health issue worldwide, particularly in Nigeria, where it has high rates of occurrence and death. Chemotherapy, a common treatment, can cause physical and emotional challenges that affect patients’ quality of life. There is a need…
Improving HIV Care for South African Men: Study Overview Background To control the HIV epidemic, it’s vital to increase HIV testing and treatment among people living with HIV (PLHIV). Unfortunately, men, especially in South Africa, are less likely to know their HIV status or begin treatment compared to women. Many men are also at a…
Centralized Colorectal Cancer Screening Outreach in Health Centers Importance Colorectal cancer (CRC) screening is effective but is not widely used in federally qualified health centers (FQHCs). Objective This study aimed to evaluate a centralized outreach program for CRC screening that included sending fecal immunochemical testing (FIT) kits by mail and providing support for follow-up colonoscopy…
Evaluating the Benefits of the EPA’s School Bus Rebate Program Introduction In the United States, around 25 million children take school buses to school. While school buses are generally safe, older buses can expose kids to harmful diesel exhaust, affecting their health and school attendance. To promote cleaner buses, the US Environmental Protection Agency (EPA)…
Better Imaging for Bone Biopsies Study Overview A recent clinical trial found that [18F]FDG PET/CT is more effective than CT for locating biopsy sites in patients with suspected bone metastases. This study involved 273 patients treated between January 2020 and March 2021. Key Findings Higher Accuracy: [18F]FDG PET/CT showed an accuracy of 97.08% compared to…
Efficacy and Safety of Prostate Radiotherapy in Metastatic Castration-Sensitive Prostate Cancer Study Overview The PEACE-1 study investigated the effects of adding radiotherapy to standard treatments for men with newly diagnosed metastatic castration-sensitive prostate cancer. This study involved 77 hospitals across Europe and included 1173 male participants. Key Findings Improved Survival: Adding radiotherapy to standard care…
Optimizing Parenting and Child Outcomes with Parent-Child Interaction Therapy-Toddler Overview Parent-Child Interaction Therapy-Toddler (PCIT-T) is a specialized therapy aimed at helping toddlers aged 12-24 months who exhibit challenging behaviors. Study Design This study used a randomized controlled trial to assess the effectiveness of PCIT-T on toddlers aged 14-24 months with disruptive behaviors. A total of…
Additive Effect of Shoulder Treatments in Adhesive Capsulitis Study Overview This study explored the effectiveness of shoulder hydrodilatation (HD) combined with suprascapular nerve blockage (SSNB) for patients with adhesive capsulitis (AC). We focused on pain relief, shoulder movement, daily function, and hand strength. Methodology Forty-eight patients diagnosed with AC participated in this study. They were…
Diagnostic Agreement Between Physiotherapists and Emergency Physicians Study Overview Patients often visit the emergency department (ED) with musculoskeletal disorders. Some hospitals now allow physiotherapists to manage these conditions independently after initial assessment. Understanding how well physiotherapists and emergency physicians agree on diagnoses is important for implementing this care model effectively. Research Findings This study analyzed…