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Potential Harms of Feedback After Web-Based Depression Screening: Secondary Analysis of Negative Effects in the Randomized Controlled DISCOVER Trial
Background Web-based depression screenings are commonly used, often providing automated…
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Intertrigo in Severe Obesity: Clinical Insights and Outcomes With a New Antimicrobial Silver-Infused Breathable Fabric
Understanding Intertrigo in Obesity Intertrigo is a skin condition that…
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Effect of Oral Insulin on Early Combined Glucose and C-Peptide Endpoints in Individuals at High-Risk for Type 1 Diabetes
Background The TrialNet Oral Insulin (OI) prevention trial did not…
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Predicting treatment outcome for complex posttraumatic stress disorder using the personalized advantage index
Background Many studies show that psychotherapy can help people with…
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Phase II Study to Evaluate the Safety and Efficacy of Neoadjuvant Chemotherapy with Weekly Paclitaxel and Carboplatin Followed by Radical Chemoradiation in Locally Advanced Cervical Cancer in Egyptian Population
Background Since 1999, the standard treatment for locally advanced cervical…
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Prospective phase II trial of first-line rituximab, methotrexate, and orelabrutinib (R-MO) in primary central nervous system lymphoma
Overview of the Study This study focuses on a new…
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An internet-delivered psychoeducational intervention (Fex-Can 2.0) targeting fertility-related distress and sexual dysfunction in young adults diagnosed with cancer: Study protocol of a randomized controlled trial with an internal pilot phase
Background Cancer and its treatments can negatively impact fertility and…
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Reliability and Acute Changes in the Load-Velocity Profile During Countermovement Jump Exercise Following Different Velocity-Based Resistance Training Protocols in Recreational Runners
Study Overview This study focused on understanding how reliable certain…
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Long-Term Efficacy and Cost-Effectiveness of Laser Tonsillotomy vs Tonsillectomy: A Secondary Analysis of a Randomized Clinical Trial
Importance of the Study The traditional treatment for tonsil issues…
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Efficacy and Safety of Fexuprazan Versus Esomeprazole for Gastroesophageal Reflux Disease-Related Chronic Cough: A Randomized, Double-Blind, Active-Controlled Exploratory Trial
Study Overview This study looked at a new type of…
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Efficacy and Safety of Generic Fluocinolone Acetonide, Hydroquinone, and Tretinoin Cream Compared With TRI-LUMA for the Treatment of Moderate-To-Severe Melasma in Chinese Patients: A Randomized, Single-Center, Placebo-Controlled Trial
Background Treatment with fluocinolone acetonide, hydroquinone, and tretinoin cream is…
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Original pericostal suture sparing the neurovascular bundle for prevention of post-thoracotomy pain syndrome after video-assisted mini-thoracotomy
Objective The goal of this study was to prevent pain…
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Dronedarone provides effective early rhythm control: post-hoc analysis of the ATHENA trial using EAST-AFNET 4 criteria
Study Overview This analysis of the ATHENA trial looked at…
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Evaluation of a combination adherence strategy to support HIV antiretroviral therapy for pregnancy and breastfeeding in Malawi: A pilot randomized clinical trial
Background Over the past 20 years, there has been significant…
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Effects of 12-Week Anti-Inflammatory Dietary Education on Depressive Symptoms Among Depressed Patients with Breast Cancer Undergoing Adjuvant Chemotherapy: A Randomized Controlled Trial
Background Many breast cancer patients experience depressive symptoms. A diet…
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Feasibility and acceptability of the Comprehensive Oncology Rehabilitation and Exercise (CORE) clinical workflow algorithm in patients with newly diagnosed stage I-III breast cancer who undergo surgery as first-line treatment
Cancer Clinical Trial Summary Background This study explored a new…
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Improved overall survival in an anti-PD-L1 treated cohort of newly diagnosed glioblastoma patients is associated with distinct immune, mutation, and gut microbiome features: a single arm prospective phase I/II trial
Clinical Trial Overview This clinical trial tested a new treatment…
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Enteric-coated Mycophenolate Sodium plus hydroxychloroquine therApy versus hydroxychloroquine for the Remission of Proteinuria in IgA Nephropathy (EMSAR-IgAN trial): study protocol for a randomised trial
Study Overview This study focuses on treating IgA nephropathy, a…
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A Cluster Randomized Controlled Trial Comparing the Efficacy of Pre-School Language Interventions-Building Early Sentences Therapy and an Adapted Derbyshire Language Scheme
“`html Background Children’s ability to use language is crucial for…
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Dark Chocolate Mitigates Premenstrual Performance Impairments and Muscle Soreness in Female CrossFit() Athletes: Evidence from a Menstrual-Phase-Specific Trial
Nutrients and Female Athletic Performance Hormonal changes during the menstrual…
