Study Overview
This study focused on finding the right dose of ciprofol, used with sufentanil, to safely sedate patients during gastroscopy procedures.
Aim of the Study
The goal was to identify the dose of ciprofol that effectively sedates 90% of patients when combined with 5 µg of sufentanil.
Study Method
This was a double-blind study involving 53 patients. The researchers adjusted the ciprofol dose based on how well the previous patient responded to sedation.
- All patients received 5 µg of sufentanil.
- The starting dose for the first patient was 0.3 mg/kg.
- If sedation was successful, the next patient received a lower dose; if not, the dose was increased.
Results
The study found that the effective dose of ciprofol was approximately 0.367 mg/kg. This was consistent across different analysis methods. While there were some changes in blood pressure and heart rate, these were not significantly different across the dose groups.
Practical Healthcare Solutions
Measurable Outcomes
Clinics should aim for the effective dose of ciprofol (0.367 mg/kg) for optimal sedation during gastroscopy.
AI Tools for Clinical Needs
Consider implementing AI solutions tailored to monitor sedation levels and patient responses during procedures.
Step-by-Step Implementation
Start with a pilot project using the findings from this study. Track patient outcomes with AI solutions to enhance sedation management in real-world settings.
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