Dr M. Trenton

“`html Beneficial Effect of Heat-Killed Lactic Acid Bacterium Lactobacillus johnsonii No. 1088 A randomized, placebo-controlled, double-blind, parallel-group clinical study was conducted to examine the effects of ingesting a heat-killed lactic acid bacterium, Lactobacillus johnsonii No. 1088 (LJ88) on temporal gastroesophageal reflux-related symptoms in healthy volunteers. A total of 120 healthy Japanese volunteers of both sexes, […] ➡️➡️➡️

“`html Study Title The Association between Circulating Cytokines and Body Composition in Frail Patients with Cardiovascular Disease Key Findings Frail patients have significantly reduced fat-free mass and a higher prevalence of diabetes. Several cytokines, including FGF basic and follistatin, showed associations with frailty. Multiple cytokines were found to correlate with fat-free mass, a key indicator […] ➡️➡️➡️

“`html Association between Homocysteine and Vitamin D Levels in Asymptomatic Korean Adults Summary An increased homocysteine level is a risk factor for cardiovascular disease, venous thromboembolism, cerebrovascular disease, and chronic kidney disease. Vitamin D deficiency is associated with coronary artery disease and metabolic disorders. The study included data from 1375 adults (895 men and 480 […] ➡️➡️➡️

Practical Solutions in Managing Glioblastoma Glioblastoma is a very aggressive and common type of brain tumor, which makes life difficult for patients. Their survival rate is usually around 15 months, despite advancements in technology and understanding of the tumors. However, molecular profiling has provided new data to better classify glioblastoma. This includes identifying mutations in […] ➡️➡️➡️

“`html Reproductive Outcomes in Young Women with Early-Stage Cervical Cancer Greater than 2 cm Undergoing Fertility-Sparing Treatment: A Systematic Review Summary Cervical cancer is a significant concern for young women. There is limited information about fertility-sparing treatment for cervical cancers larger than 2 cm. This review aimed to assess the reproductive outcomes of women with […] ➡️➡️➡️

“`html GNB1 Encephalopathy: Clinical Case Report and Literature Review Highlights Rare genetic disease caused by pathogenic variants in the GNB1 gene Only around 68 cases documented worldwide Main symptoms include mild developmental delay, cognitive impairment, dystonia, and nystagmus Diagnosis relies on genetic testing due to low specificity of symptoms No standardized treatment guidelines available Deep […] ➡️➡️➡️

“`html Transitioning to Personalized Care in Small-Cell Lung Cancer (SCLC) International Journal of Molecular Sciences, April 10, 2024 Summary: Lung cancer is a major concern worldwide, especially small-cell lung cancer (SCLC) which grows rapidly and is often diagnosed at an advanced stage. Recent clinical trials have shown that using immune checkpoint inhibitors in first-line chemotherapy […] ➡️➡️➡️

“`html Potential Benefits of Photon-Counting CT in Dental Imaging: A Narrative Review Background/Objectives: Photon-counting computed tomography (PCCT) is a new technology improving dental diagnosis and treatment planning. PCCT offers high resolution, improved soft-tissue contrast, and faster scanning times, essential for detailed dental diagnosis and treatment planning. It uses semiconductor detectors to produce sharper images and […] ➡️➡️➡️

“`html Fluorescence-Guided Laparoscopy for Staging of Gastric Cancer Practical Solutions and Value Hypericin, a fluorescent compound from plants, was tested to improve visualization of peritoneal metastasis (PM) in gastric cancer (GC) through laparoscopy. Study aimed to assess safety and feasibility of oral hypericin and the effectiveness of fluorescence-guided laparoscopy (FGL) for staging GC. Patients received […] ➡️➡️➡️

“`html Exploring the Link between Anticoagulation, Cognitive Impairment and Dementia in Atrial Fibrillation: A Systematic Review Background The review aims to understand how anticoagulants affect cognitive function and dementia in atrial fibrillation patients. Methods SCOPUS and PubMed were searched for English articles on OACs and cognitive impairment/dementia in AF patients. Non-original research and studies without […] ➡️➡️➡️

“`html Neutrophil Extracellular Traps and Respiratory Disease Practical Solutions and Value Neutrophil extracellular traps (NETs) play a crucial role in the initial immune response to infection but can also contribute to tissue damage due to their highly inflammatory nature. NETs are particularly relevant to lung diseases, and their presence has been demonstrated in conditions such […] ➡️➡️➡️

“`html Sonography as a Diagnostic Tool in Midurethral Sling Complications: A Narrative Review Key Points: Midurethral slings (MUS) are a common treatment for stress urinary incontinence (SUI) but can lead to postoperative complications. Sonography is a valuable tool for diagnosing complications from MUS procedures. This review examines the use of pelvic floor ultrasound in identifying […] ➡️➡️➡️

“`html Insights on Corneal Neurotization for Neurotrophic Keratopathy Practical Solutions and Value Neurotrophic keratopathy (NK) results from corneal denervation due to various trigeminal nerve dysfunctions. Modern corneal neurotization (CN) techniques aim to restore corneal sensitivity with less invasive options. Donor nerve selection and preparation are crucial for surgical success and often require multidisciplinary teams. Key […] ➡️➡️➡️

“`html Natural History of Retinal Sensitivity Loss in Diabetic Macular Ischemia Practical Solutions and Value This study observed how retinal sensitivity changes over one year in diabetic macular ischemia. Researchers recruited patients with stable-treated proliferative diabetic retinopathy and evidence of macular ischemia. They used microperimetry to assess retinal sensitivity at the beginning and end of […] ➡️➡️➡️

“`html Smoking and Lung Cancer Prognosis Recent research from the National Lung Screening Trial suggests that smoking behaviors at the time of lung cancer diagnosis can impact the stage of the cancer and the patient’s prognosis. Key Findings: Current smokers and those who smoke shortly after waking up tend to have more advanced-stage lung cancer. […] ➡️➡️➡️

“`html The Impact of Laparoscopic Myomectomy on Pregnancy Outcomes: A Systematic Review Study Objective: Investigate how laparoscopic myomectomy techniques affect pregnancy outcomes Focus on the correlation between suture type and uterine rupture incidence Examine how myoma localization and size influence fertility outcomes Data Sources: MDPI, PubMed, Web of Science, and Cochrane Library databases from 2008 […] ➡️➡️➡️

Targeted Nanoparticle-Based Diagnostic and Treatment Options for Pancreatic Cancer Cancers (Basel). 2024 Apr 20;16(8):1589. doi: 10.3390/cancers16081589. ABSTRACT Pancreatic cancer is difficult to diagnose and treat due to its aggressive nature and lack of early detection methods. The dense stroma around the tumor makes drug delivery challenging. Nanotechnology can provide solutions by creating new drug delivery […] ➡️➡️➡️

Latest Insights and Therapeutic Advances in Myelodysplastic Neoplasms Published in Cancers (Basel) on April 19, 2024 Myelodysplastic syndromes/neoplasms (MDSs) are a group of blood cancers that often affect older people. Changes in the genes of blood stem cells cause these diseases. New research on the genes of MDS has given us important information about how […] ➡️➡️➡️

Molecular Landscape and Therapeutic Strategies against Colorectal Cancer Molecular Landscape and Therapeutic Strategies against Colorectal Cancer Practical Solutions and Value Colorectal cancer (CRC) is the second leading cause of cancer deaths worldwide. Incidence of young-onset CRC (diagnosis before age 50) is increasing. Improved outcomes for CRC patients due to comprehensive molecular characterization of tumors and […] ➡️➡️➡️

“`html The Prognostic Value of Blood Test Indices in Cervical Cancer Patients Introduction: There is increasing interest in using routine blood tests like RDW and SII to predict survival in cancer patients receiving radiotherapy. This study aimed to assess the connection between pre-treatment RDW and SII levels and overall survival (OS) in patients with localized […] ➡️➡️➡️