Evaluating the impact of platelet-rich plasma injection in spinal endoscopic nucleotomy on MRI pfirrmann grading and clinical outcomes in lumbar disc herniation

Evaluating Platelet-Rich Plasma Injection in Spinal Surgery

Study Overview

This study looks at how effective and safe it is to use platelet-rich plasma (PRP) injections along with a specific spinal surgery known as percutaneous endoscopic nucleotomy for treating lumbar disc herniation (LDH) in younger adults.

Study Details

Between April 2022 and September 2023, 60 patients with LDH were split into two groups of 30. One group received both the spinal surgery and PRP injections, while the other group only had the surgery. Patient pain levels and disability scores were measured before and after surgery at three key times: 3 days, 3 months, and 6 months. MRI scans were also done to check the condition of the disc.

Key Findings

  • All patients were followed for at least six months.
  • Both groups showed significant improvements in pain and disability scores after surgery.
  • The group that received PRP injections had better recovery results after three days compared to the surgery-only group.
  • By the end of the study, the PRP group showed better MRI results.
  • Both groups had similar rates of positive outcomes (excellent or good), with no complications reported.

Conclusion

Combining spinal surgery with PRP injections appears to be a safe and effective approach for treating LDH in younger adults, enhancing recovery after the procedure.

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