Dr M. Trenton

Trial Results Explained The recent trial studied two drugs, gantenerumab and solanezumab, for treating dominantly inherited Alzheimer disease (DIAD). Here’s what we found: What Worked: Gantenerumab significantly reduced the amount of amyloid-beta (Aβ) deposits in the brain compared to no treatment. This reduction was seen in many brain areas. What Didn’t Work: There were no […] ➡️➡️➡️

Trial Results Explained The clinical trial tested a new cream called NuGel for treating mild to moderate atopic dermatitis (AD). Here’s what we found: What Worked: NuGel, especially the 0.3% version, showed a significant reduction in skin symptoms, as measured by the EASI score. Patients tolerated it well with no serious side effects. What Didn’t […] ➡️➡️➡️

Understanding the Trial Results This research looked at two cancer treatment plans for patients with nonmetastatic gastric adenocarcinoma, a serious type of stomach cancer. The two plans compared were FLOT and modified DCF (mDCF). What Worked? The FLOT treatment showed better results, with more patients responding positively to the therapy. Patients on FLOT had fewer […] ➡️➡️➡️

Study Overview This study looked at how simulation-based education can help Afghan women learn about breast cancer. The goal was to improve their knowledge of breast cancer risks, signs, and self-examination skills. What Worked? The training helped women feel more confident about breast cancer awareness. Participants learned important self-examination skills. The results showed a significant […] ➡️➡️➡️

Understanding the Trial Results This study looked at how depression and positivity affect survival in patients with advanced cancer. Here’s what they found: What Worked: Patients with advanced cancer who had high levels of positivity coping strategies had a better survival rate, even if they experienced depression. What Didn’t Work: Patients with low levels of […] ➡️➡️➡️

Understanding the Trial Results This study looked at how adding zinc or vitamin D to a common treatment for oral lichen planus (OLP) affects patients. OLP is a long-term condition that causes painful sores in the mouth. The main findings are: Patients who received zinc along with their usual treatment reported less pain by Week […] ➡️➡️➡️

Understanding the Trial Results The study looked at using a probiotic called Saccharomyces boulardii along with the antibiotic vancomycin to treat Clostridioides difficile infection (CDI). Here’s what we found: What Worked: The combination of S. boulardii and vancomycin showed a higher overall cure rate and reduced the chances of the infection coming back. What Didn’t […] ➡️➡️➡️

Understanding the Trial Results The study looked at whether using a preoperative enema before anal surgery helps patients. Here’s what we found: What Worked? For most patients, using a preoperative enema did not make a difference in pain levels or complications after surgery. Patients who had a specific type of surgery (Milligan-Morgan haemorrhoidectomy) reported less […] ➡️➡️➡️

Understanding the Study Results This study looked at different ways to treat melasma, a common skin condition. Melasma can be hard to treat because existing treatments often have side effects and don’t always work well. The researchers tested a new form of tranexamic acid (TXA) using nanotechnology, which helps the medicine penetrate the skin better. […] ➡️➡️➡️

Understanding the Trial Results What Worked? Pramipexole showed some improvement in reducing depressive symptoms in patients with treatment-resistant bipolar depression. Positive effects were noted on mood and psychosocial function over time. Patients experienced improvements in quality of life and well-being. What Didn’t Work? The difference in effectiveness between pramipexole and a placebo was not statistically […] ➡️➡️➡️

Trial Results Explained The study looked at how well a new type of nutrition, called LEOVIT ONCO, helps patients with esophageal and gastric cancer who are not getting enough protein and energy. Here’s what they found: What Worked: Patients who used LEOVIT ONCO showed better improvements in their body weight and protein levels compared to […] ➡️➡️➡️

Understanding the Trial Results The study looked at how effective cardiac rehabilitation is for patients who have had an acute coronary syndrome (ACS), which is a serious heart condition. Here’s what they found: What Worked Patients in the cardiac rehabilitation program followed dietary guidelines better (73.5% vs. 52.4%). They were more active physically (85.3% vs. […] ➡️➡️➡️

Understanding the Trial Results The PREVENTOMICS study looked at how effective personalized nutrition plans are for adults with overweight and obesity in Poland and the UK. Here’s what we found: What Worked? Personalized nutrition plans combined with behavioral changes (PP+B) showed potential for cost-effectiveness in Poland and the UK. Both PP+B and personalized plans (PP) […] ➡️➡️➡️

Summary of the Trial Results This study looked at how different ways of informing Latina women about their breast density after a mammogram affected their feelings about breast cancer. The research included three methods of communication: regular mail, mail with extra educational materials, and one-on-one support from a community health worker. What Worked? None of […] ➡️➡️➡️

Understanding the Trial Results This study looked at factors that can predict how successful rapid maxillary expansion (RME) will be in late adolescents. Here’s what the results mean: What Worked? Patients with higher maturity stages of the midpalatal suture (MSM) and cervical vertebrae (CVM) had a higher chance of RME failure. Patients with a lower […] ➡️➡️➡️

Understanding the Trial Results The study looked at two ways to help children who have a cardiac arrest outside of a hospital. One method used a device called i-gel® for airway management, while the other used a bag-valve-mask. Here’s what we found: What Worked: Both methods provided similar levels of ventilation, meaning they both helped […] ➡️➡️➡️

Understanding the Study Results This study looked at how certain personality traits affect how women cope with breast cancer. The main focus was on: Self-Criticism: Being hard on oneself. Dependency: Relying on others for support. Efficacy: Feeling capable and effective. The results showed that: Women who were more self-critical had a harder time functioning, felt […] ➡️➡️➡️