Dr M. Trenton

Background American Indians face significant health challenges, particularly high rates of Type 2 diabetes (T2D). To address this issue, we launched a program called Together Overcoming Diabetes (TOD), which focuses on culturally relevant, home-based prevention strategies. Study Overview This study involves collaboration between five tribal nations and university researchers, starting in 2021. We are conducting […] ➡️➡️➡️

Background Excess fat in the liver can lead to a condition called metabolic dysfunction-associated steatotic liver disease (MASLD). This study looked at how weight loss affects fat buildup in the liver. Study Overview Overweight adults with either high or normal liver fat were given dietary counseling for 6 months. Researchers measured various factors to understand […] ➡️➡️➡️

Understanding Acute Pancreatitis Acute pancreatitis (AP) is a serious condition that needs quick diagnosis and treatment. Correctly assessing how severe the condition is helps in providing the right care at the start. Aim of the Study This study looks at how effective certain inflammatory markers and scoring systems are in determining the severity of early-phase […] ➡️➡️➡️

Overview of the Study Total knee arthroplasty (TKA) is important for relieving pain and enhancing life quality in patients with severe knee arthritis. However, many patients experience sleep problems after surgery, which can last for months and affect recovery. Robotic-Assisted TKA vs. Conventional TKA This study compared sleep quality in patients who underwent robotic-assisted TKA […] ➡️➡️➡️

Study Overview This study aims to explore the benefits of acupuncture for people suffering from diarrhoea-predominant irritable bowel syndrome (IBS-D). Although some research suggests acupuncture may help, there are not many high-quality studies available. We want to find out how effective and safe personalised acupuncture is for IBS-D patients. Study Design The research will involve […] ➡️➡️➡️

Background In patients with acute myeloid leukaemia (AML), finding measurable residual disease (MRD) usually means a poor outlook. This study looked at whether changing treatment based on MRD results could help patients live longer. Methods We studied patients aged 16-60 with newly diagnosed AML in the UK, Denmark, and New Zealand. We checked for specific […] ➡️➡️➡️

Background Web-based depression screenings are commonly used, often providing automated feedback to users. However, there are concerns about potential negative effects, and clear evidence is lacking. Objective The goal of this study was to investigate if automated feedback after screening could lead to: Misdiagnosis Mistreatment Worsening depression Negative emotional responses Increased suicidal thoughts Methods This […] ➡️➡️➡️

Understanding Intertrigo in Obesity Intertrigo is a skin condition that often goes unnoticed in people with obesity. This condition can cause discomfort and skin irritation in areas where skin rubs together. Study Overview This study aimed to find out how common intertrigo is among obese patients and to see how effective a special moisture-wicking fabric […] ➡️➡️➡️

Background The TrialNet Oral Insulin (OI) prevention trial did not show a clear overall benefit when looking at type 1 diabetes as the main goal. However, a delay in the onset of diabetes was observed in a specific group of participants at high risk. Study Overview This analysis focused on a new approach to measure […] ➡️➡️➡️

Background Many studies show that psychotherapy can help people with posttraumatic stress disorder (PTSD). However, not everyone responds the same way to treatment, especially those with complex PTSD (CPTSD). We need better ways to match patients to the treatments that will help them the most. Objective The goal of this study was to create a […] ➡️➡️➡️

Background Since 1999, the standard treatment for locally advanced cervical cancer has been platinum-based chemoradiation (CRT). However, this treatment only improves overall survival by 6% over five years compared to radiotherapy alone. Many patients (30-40%) do not respond completely to CRT, indicating a need for better treatment options. New Approach A new method called Neoadjuvant […] ➡️➡️➡️

Overview of the Study This study focuses on a new treatment for primary central nervous system lymphoma (PCNSL), a type of blood cancer that is hard to treat due to the protective barrier in the brain. The treatment being tested is called the R-MO regimen, which includes rituximab, high-dose methotrexate, and orelabrutinib. Key Findings A […] ➡️➡️➡️

Background Cancer and its treatments can negatively impact fertility and sexual health. However, there are few proven ways to help those affected. This study introduces Fex-Can 2.0, an online program designed to support young adults with cancer by addressing fertility-related worries and sexual issues. Study Goals The main goal of this study is to see […] ➡️➡️➡️

Study Overview This study focused on understanding how reliable certain measurements are when using a specific exercise called the countermovement jump. It also looked at how well these measurements can show changes in strength after different training methods. Key Findings Twenty-one recreational runners participated in four different training sessions. Each session involved performing back squats […] ➡️➡️➡️

Importance of the Study The traditional treatment for tonsil issues in adults, called tonsillectomy (TE), often requires a long and difficult recovery period. Objective of the Study This study aimed to compare the long-term effectiveness and cost of a new treatment called carbon dioxide (CO2) laser tonsillotomy (TO) with the standard tonsillectomy. Study Overview The […] ➡️➡️➡️

Study Overview This study looked at a new type of medication called potassium-competitive acid blockers (P-CABs), specifically fexuprazan, to see how well it works for people with chronic cough related to gastroesophageal reflux disease (GERD). Study Details In this trial, adults with a chronic cough lasting at least 8 weeks and a recent diagnosis of […] ➡️➡️➡️

Background Treatment with fluocinolone acetonide, hydroquinone, and tretinoin cream is considered the best option for melasma. However, we need more information about how this treatment works for Chinese patients, as their skin may respond differently than that of Caucasian patients. Aim The goal of this study was to assess how effective and safe fluocinolone acetonide, […] ➡️➡️➡️

Objective The goal of this study was to prevent pain after thoracic surgery by using a new type of stitching technique that avoids damaging important nerves and blood vessels. Materials and Methods A clinical trial was conducted with 71 patients undergoing lung surgery using video assistance. These patients were divided into two groups: one received […] ➡️➡️➡️

Study Overview This analysis of the ATHENA trial looked at how dronedarone (400 mg twice daily) affects heart health in patients with early atrial fibrillation (AF) and other heart-related issues. Key Findings Fewer Serious Events: Patients taking dronedarone had fewer cardiovascular deaths, strokes, and hospitalizations due to heart failure or acute coronary syndrome compared to […] ➡️➡️➡️

Background Over the past 20 years, there has been significant progress in preventing the transmission of HIV from mothers to their babies, thanks to the widespread availability of antiretroviral therapy (ART). However, new infections in children still occur. Study Overview In a pilot study conducted in Lilongwe, Malawi, we tested a support package designed to […] ➡️➡️➡️