Dr M. Trenton

Understanding the Trial Results The trial tested a medication called dapagliflozin for people with metabolic dysfunction-associated steatohepatitis (MASH). Here’s what the results mean: What Worked? 53% of participants taking dapagliflozin showed improvement in MASH without worsening liver fibrosis. 23% of those on dapagliflozin had complete resolution of MASH without worsening fibrosis. 45% experienced improvement in […] ➡️➡️➡️

Understanding the Trial Results The recent study looked at a lotion combining halobetasol propionate and tazarotene to treat a type of psoriasis known as hyperkeratotic plaques. Here’s what we learned: What Worked: The lotion was effective in reducing the thickness and scaling of plaques in patients. Those who used this lotion saw better results than […] ➡️➡️➡️

Understanding the Trial Results The recent trials showed that tapinarof cream, applied once daily, is effective in relieving itch for people with atopic dermatitis (AD). This cream works quickly, providing noticeable relief within the first day. Here’s what we learned: What Worked: Tapinarof significantly reduced itchiness, starting as early as 24 hours after the first […] ➡️➡️➡️

Understanding the Trial Results This study focused on a video game called “Night Shift,” designed to help doctors better identify serious injuries in trauma patients. Here’s what we found: What Worked Doctors who played the video game showed a significant reduction in missing serious injuries (22% compared to 38% in the control group). The game […] ➡️➡️➡️

Understanding the Trial Results The study compared two methods for cervical epidural injections: the Loss-of-Resistance (LOR) technique and the Hanging Drop (HD) technique. Here’s what the results mean: What Worked? The LOR technique was found to be more successful than the HD technique for cervical injections. Patients who received injections on the right or left […] ➡️➡️➡️

Understanding the Trial Results This clinical trial compared two treatments for knee osteoarthritis: platelet-rich plasma (PRP) injections and radiofrequency ablation of genicular nerves (GNRFA). The findings help us see what works best for patients dealing with knee pain. What Worked? PRP Injections: Patients who received PRP injections reported significantly lower pain levels and a better […] ➡️➡️➡️

Understanding the Trial Results This study looked at how exercise and medication affect a blood marker called C-terminal agrin fragment (CAF), which is linked to muscle health in older adults. Here’s what we found: What Worked: Regular heavy resistance exercise (48 sessions) improved muscle strength by 13%-17% over 16 weeks. Taking the medication losartan increased […] ➡️➡️➡️

Trial Results Explained The trial looked at whether early treatment for HIV, along with a special antibody called VRC01, could help women in southern Africa control the virus without ongoing medication. Here’s what we found: What Worked: 18% of the women who stopped their antiretroviral therapy (ART) were able to control the virus for at […] ➡️➡️➡️

Understanding the Study Results The study focused on helping surgeons in county-level hospitals in China learn the most recent guidelines for breast cancer diagnosis and treatment. It looked at two training methods: one using case-based learning (CBL) alone and the other combining CBL with the PDCA cycle (Plan-Do-Check-Act). What Worked? Both training methods improved surgeons’ […] ➡️➡️➡️

Understanding the Trial Results This study looked at how stationary cycling with a special feedback system can help people with knee osteoarthritis (OA). Here’s what they found: What Worked: Both groups, those with feedback and those without, reported less knee pain and better knee function after six weeks of cycling. What Didn’t Work: Muscle strength […] ➡️➡️➡️

Understanding the Study Results The study looked at whether a special program could help nursing home doctors safely reduce the use of antidepressants in older residents with dementia. Here’s what they found: What Worked? The study involved training for nursing home doctors and provided tools to help them talk with staff and reflect on their […] ➡️➡️➡️

Understanding the Study Results This study looked at how therapeutic art activities can help teenagers with type 1 diabetes feel less anxious and improve their mental well-being. Here’s what we found: The teenagers who took part in art activities showed much lower anxiety levels compared to those who didn’t. Their psychological well-being scores were also […] ➡️➡️➡️

Trial Results Summary The study looked at how using self-made breast models can improve communication between doctors and patients with breast cancer. In the trial, 200 patients were divided into two groups: Control Group: Received traditional explanations from doctors. Model Group: Used self-made breast models to help understand the information. The results showed that: The […] ➡️➡️➡️

Understanding the Trial Results This study looked at how patients with psoriatic arthritis (PsA) responded to a medication called tofacitinib. The researchers found five different groups of patients based on how their disease activity changed over six months: Group 1: Patients improved from moderate disease activity to very low or low activity. Group 2: Patients […] ➡️➡️➡️

Understanding the Trial Results The study looked at how eating sake lees, a byproduct of sake brewing, might help people with chronic constipation and kidney health. Here’s what we found: What Worked? Sake lees intake seemed to reduce certain harmful substances in the body. Participants reported less constipation, with scores improving significantly. Levels of D-alanine, […] ➡️➡️➡️

What Worked in the Trial? The study showed that using a WeChat mini program for 10 weeks helped Chinese patients with cardiovascular diseases (CVDs) make important health changes. Here are the key improvements: More Physical Activity: Patients increased their moderate to vigorous physical activity significantly. Better Eating Habits: There was a noticeable rise in fruit […] ➡️➡️➡️

Trial Results Explained The recent trial studied two drugs, gantenerumab and solanezumab, for treating dominantly inherited Alzheimer disease (DIAD). Here’s what we found: What Worked: Gantenerumab significantly reduced the amount of amyloid-beta (Aβ) deposits in the brain compared to no treatment. This reduction was seen in many brain areas. What Didn’t Work: There were no […] ➡️➡️➡️

Trial Results Explained The clinical trial tested a new cream called NuGel for treating mild to moderate atopic dermatitis (AD). Here’s what we found: What Worked: NuGel, especially the 0.3% version, showed a significant reduction in skin symptoms, as measured by the EASI score. Patients tolerated it well with no serious side effects. What Didn’t […] ➡️➡️➡️

Understanding the Trial Results This research looked at two cancer treatment plans for patients with nonmetastatic gastric adenocarcinoma, a serious type of stomach cancer. The two plans compared were FLOT and modified DCF (mDCF). What Worked? The FLOT treatment showed better results, with more patients responding positively to the therapy. Patients on FLOT had fewer […] ➡️➡️➡️