Clinical trials

“`html Natural History of Retinal Sensitivity Loss in Diabetic Macular Ischemia Practical Solutions and Value This study observed how retinal sensitivity changes over one year in diabetic macular ischemia. Researchers recruited patients with stable-treated proliferative diabetic retinopathy and evidence of macular ischemia. They used microperimetry to assess retinal sensitivity at the beginning and end of […] ➡️➡️➡️

“`html Smoking and Lung Cancer Prognosis Recent research from the National Lung Screening Trial suggests that smoking behaviors at the time of lung cancer diagnosis can impact the stage of the cancer and the patient’s prognosis. Key Findings: Current smokers and those who smoke shortly after waking up tend to have more advanced-stage lung cancer. […] ➡️➡️➡️

“`html The Impact of Laparoscopic Myomectomy on Pregnancy Outcomes: A Systematic Review Study Objective: Investigate how laparoscopic myomectomy techniques affect pregnancy outcomes Focus on the correlation between suture type and uterine rupture incidence Examine how myoma localization and size influence fertility outcomes Data Sources: MDPI, PubMed, Web of Science, and Cochrane Library databases from 2008 […] ➡️➡️➡️

Targeted Nanoparticle-Based Diagnostic and Treatment Options for Pancreatic Cancer Cancers (Basel). 2024 Apr 20;16(8):1589. doi: 10.3390/cancers16081589. ABSTRACT Pancreatic cancer is difficult to diagnose and treat due to its aggressive nature and lack of early detection methods. The dense stroma around the tumor makes drug delivery challenging. Nanotechnology can provide solutions by creating new drug delivery […] ➡️➡️➡️

Latest Insights and Therapeutic Advances in Myelodysplastic Neoplasms Published in Cancers (Basel) on April 19, 2024 Myelodysplastic syndromes/neoplasms (MDSs) are a group of blood cancers that often affect older people. Changes in the genes of blood stem cells cause these diseases. New research on the genes of MDS has given us important information about how […] ➡️➡️➡️

Molecular Landscape and Therapeutic Strategies against Colorectal Cancer Molecular Landscape and Therapeutic Strategies against Colorectal Cancer Practical Solutions and Value Colorectal cancer (CRC) is the second leading cause of cancer deaths worldwide. Incidence of young-onset CRC (diagnosis before age 50) is increasing. Improved outcomes for CRC patients due to comprehensive molecular characterization of tumors and […] ➡️➡️➡️

“`html The Prognostic Value of Blood Test Indices in Cervical Cancer Patients Introduction: There is increasing interest in using routine blood tests like RDW and SII to predict survival in cancer patients receiving radiotherapy. This study aimed to assess the connection between pre-treatment RDW and SII levels and overall survival (OS) in patients with localized […] ➡️➡️➡️

“`html Study Title: Spatial profiling of ovarian carcinoma and tumor microenvironment evolution under neoadjuvant chemotherapy Purpose Investigate changes in immune tumor microenvironment (iTME) in ovarian cancer patients undergoing neoadjuvant chemotherapy (NACT) Correlate changes in immune cell subsets and coregulators with clinical outcomes Experimental Design Used multiplexed immune profiling and cell clustering analysis on paired ovarian […] ➡️➡️➡️

“`html Characterizing Technology Use and Preferences for Health Communication in South Asian Immigrants With Prediabetes or Diabetes: Cross-Sectional Descriptive Study JMIR Form Res. 2024 Apr 26;8:e52687 Background: Type 2 diabetes is a significant concern for South Asian groups. Lifestyle programs can help manage diabetes, but they need to be adapted for mobile health (mHealth). Objective: […] ➡️➡️➡️

“`html Protocol for a Prospective Noninterventional Study Importance of Early Detection of Preeclampsia in Pregnant Women Preeclampsia affects 2%-8% of pregnancies and can lead to high maternal and fetal mortality rates due to late identification. Misfolded proteins in urine samples may serve as a promising biomarker for predicting preeclampsia. Study Objectives and Methods Evaluate the […] ➡️➡️➡️

“`html Summary of Clinical Trial Results A study was conducted to evaluate the effectiveness of an educational program using technology-enhanced learning to teach neurology residents how to identify interictal epileptiform discharges (IEDs). Methods Junior neurology residents were randomly assigned to three groups: control, intervention 1, and intervention 2. The intervention involved video tutorials and rating […] ➡️➡️➡️

“`html Feasibility of Exergaming for Upper Extremity Rehabilitation in People with Multiple Sclerosis: Prospective Clinical Trial Background Exergaming has been suggested as a more motivational rehabilitation method for people with multiple sclerosis (MS). However, the lack of specific scenarios designed for people with MS is a major disadvantage. Objectives This study aims to assess the […] ➡️➡️➡️

“`html Predisposing, Precipitating, and Perpetuating Factors of Insomnia in Cancer Survivors Objective To identify the factors contributing to insomnia in cancer survivors, including those that make it more likely, those that trigger it, and those that maintain it at subthreshold, moderate, and severe levels. Sample & Setting 135 cancer survivors participating in a clinical trial […] ➡️➡️➡️

Diagnostic Performance of Fluorescein-Guided Sentinel Lymph Node Biopsy in Early Breast Cancer Practical Solutions and Value Traditional methods for evaluating axillary lymph nodes in early breast cancer are resource-intensive. Fluorescein Sodium (FS)-guided sentinel lymph node biopsy (SLNB) offers a low-cost alternative. Meta-analysis shows a high Sentinel Lymph Node Identification Rate (SLN-IR) of 93% and a […] ➡️➡️➡️

“`html Measuring critical force in sport climbers: a validation study of the 4 min all-out test on finger flexors PURPOSE Study aimed to validate critical force (CF) for finger flexors derived from the 4 min all-out test as a boundary for the highest sustainable work intensity in sport climbers. METHODS Twelve participants performed the 4 […] ➡️➡️➡️

Document Factors Affecting Physical Activity in Pediatric Cancer Survivors Published in: Eur J Pediatr. 2024 Apr 26. DOI: 10.1007/s00431-024-05584-6 Abstract Pediatric cancer survivors (PCS) with overweight and obesity are at risk for secondary chronic diseases. Despite the benefits of physical activity (PA) after treatment, PCS have low PA levels. This highlights the need for lifestyle […] ➡️➡️➡️

“`html Evaluation of Large Language Models in Breast Cancer Clinical Scenarios Practical Solutions and Value Large language models (LLMs) like GPT-3.5, GPT-4.0, and Claude2 have shown potential in breast cancer diagnosis, treatment, and care. A study compared the performances of these LLMs in clinical scenarios related to breast cancer. Clinical scenarios were categorized into assessment […] ➡️➡️➡️

“`html Study Title The Acute Effects of Ball Pressure on Anticipation Timing Following a Series of Purposeful Headers in Adult Football (Soccer) Players Objective To investigate the immediate impact of ball pressure on anticipation timing after purposeful headers in adult soccer players. Practical Solutions Use of lower-pressure and higher-pressure match balls for headers Assessment of […] ➡️➡️➡️

“`html Practical Solutions and Value of SoftVue Breast Tomographic Ultrasound (BTUS) This clinical trial article highlights the practical solutions and value of SoftVue BTUS in breast cancer screenings and theranostic treatments. Key Insights and Vision Review provides unique insights into the scientific scope and clinical vision of SoftVue BTUS inventors and pioneers. Over 20-year collaboration […] ➡️➡️➡️

“`html An Evaluation of Racial and Ethnic Representation in Research Conducted with Young Adults Diagnosed with Cancer Practical Solutions and Value Research found that young adults with cancer from diverse racial and ethnic groups are under-represented, leading to incomplete understanding of their psychosocial outcomes. Using data from the Young Adults with Cancer in Their Prime […] ➡️➡️➡️