Clinical trials

“`html Research Summary In a study published in Nutr Metab Cardiovasc Dis, researchers investigated the use of lipid-lowering therapy (LLT) and lifestyle changes in patients with atherosclerotic cardiovascular disease (ASCVD) who had high levels of low-density lipoprotein cholesterol (LDL-C). Key Findings Out of 1091 ASCVD patients with high LDL-C levels, 51% were not using LLT […] ➡️➡️➡️

“`html Study Summary Patients with nonalcoholic fatty liver disease (NAFLD) are at higher risk of cardiac events. This study aimed to determine if noninvasive liver fibrosis scores can predict cardiac events in NAFLD patients. Methods 4071 NAFLD patients were assessed using ultrasonography. Liver fibrosis was categorized into three groups based on the Fibrosis-4 (FIB4) index […] ➡️➡️➡️

Practical Solutions and Value in Clinical Trials Publication Details Title: Br J Gen Pract Date: April 25, 2024 Volume: 74 Issue: 742 Pages: 202-203 DOI: 10.3399/bjgp24X737109 Print Date: May 2024 PMID: 38664056 This publication provides insight into practical solutions and value in the field of clinical trials, offering valuable information for medical professionals and researchers […] ➡️➡️➡️

“`html Study on Neurological Disorders and Breast Cancer Risk Background: Previous research suggests a possible link between neurological disorders like Alzheimer’s disease and multiple sclerosis and the risk of breast cancer. However, the exact relationship is not clear. This study aimed to investigate if these neurological conditions affect the overall risk of breast cancer and […] ➡️➡️➡️

“`html Study Summary: Idiopathic Intracranial Hypertension Headache Key Findings: Sensitivity of ICHD-3 criteria for idiopathic intracranial hypertension headache: 93% Specificity of ICHD-3 criteria for idiopathic intracranial hypertension headache: 100% Headache phenotype not distinct in idiopathic intracranial hypertension Implications and Practical Solutions: ICHD-3 criteria are both sensitive and specific for idiopathic intracranial hypertension headache Recommendation to […] ➡️➡️➡️

“`html Study Summary: Impact of Allogeneic Hematopoietic Cell Transplantation on Patients with FLT3-ITDmut+ AML Background Allogeneic hematopoietic cell transplantation (alloHCT) is used to treat patients with acute myeloid leukemia (AML) with FLT3-ITD mutation, but the impact of different characteristics on outcomes after transplant is not fully understood. Objective To determine the impact of patient, disease, […] ➡️➡️➡️

“`html Research Summary: Understanding Human Judgments of Similarity and Difference In a recent study published in Cognition Psychology, researchers investigated the asymmetry in human judgments of similarity and difference. They found that judgments of similarity were more sensitive to relational overlap compared to judgments of difference. The study aimed to explain this asymmetry by focusing […] ➡️➡️➡️

Bladder Cancer and Immunotherapy Bladder cancer (BC) is a common type of cancer in the urinary system. It is often difficult to treat effectively. Immunotherapy, which uses the body’s immune system, has shown promise in early clinical trials. A specific type of immune cell called mucosal associated invariant T (MAIT) cells, which is involved in […] ➡️➡️➡️

“`html Study Summary Recent studies have found that chest CT scans can be beneficial for lung cancer screening. During the COVID-19 pandemic, many chest CT scans were performed on a large population. This study aimed to describe the incidence and characteristics of lung cancer detected on chest CT scans done for suspected or confirmed COVID-19 […] ➡️➡️➡️

“`html SLC6A1-Related Neurodevelopmental Disorder (SLC6A1-NDD) Clinical Trial Readiness Study Overview SLC6A1-NDD is a rare genetic disorder linked to autism spectrum disorder, epilepsy, and developmental delay. Understanding the impact on patients and families is crucial for future clinical trials. Quality-of-Life (QoL) Measures QoL measures capture the overall disease experience of patients. This study presents QoL findings […] ➡️➡️➡️

“`html Study on Bipolar Disorder Medication and Physical Disorders Key Findings: Bipolar disorder is linked to higher rates of physical disorders. Study compared the effects of lithium, lamotrigine, and valproate on physical disorders. No significant differences found in the risk of physical disorders between the medications, except for myxedema. Lithium use was associated with a […] ➡️➡️➡️

“`html Summary of Clinical Trial Findings Study Details Prospective cohort study with 98,459 participants aged 55 and over Mean follow-up time of 8.8 years Data from the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial Key Findings Adherence to a low-fat diet (LFD) associated with reduced risk of lung cancer, especially in smokers High […] ➡️➡️➡️

“`html Study Summary Distress is common among cancer patients, and many do not receive the support they need. The study aimed to test the effectiveness of Mika, a digital app, in reducing distress in cancer patients. Methods Patients with cancer in Germany were enrolled in a trial. Participants were split into two groups: one using […] ➡️➡️➡️

“`html Study Overview Patients with atrial fibrillation (AF) who have had an ischemic stroke are at high risk for further clinical events. Taking direct oral anticoagulants (DOAC) is important for preventing these events, but some patients may not take their medication as prescribed. This study looked at how well stroke survivors with AF adhered to […] ➡️➡️➡️

“`html Study on Electroacupuncture for Diabetic Peripheral Neuropathy Background Diabetic peripheral neuropathy (DPN) is a common complication of diabetes, but current treatments have limitations. Electroacupuncture (EA) is being considered as an alternative treatment for DPN, but its effectiveness and safety are not well-established. Methods Searching for relevant studies in English and Chinese databases. Using RevMan5.3 […] ➡️➡️➡️

“`html Practical Solutions for Frequency Decomposition of Physiological Signals Summary Physiological processes often exhibit cyclical patterns, but analyzing these patterns can be challenging when the data is sparse and irregularly sampled. A new model called basis pursuit denoising with polynomial detrending (BPWP) has been developed to address this issue. It effectively recovers oscillations and trends […] ➡️➡️➡️

“`html Study on Dietary Screening Tool for Hypertension Risk in Nigeria Key Findings: Food frequency questionnaires (FFQs) can effectively assess dietary risks for hypertension in West Africa. The study involved 58 adult patients with hypertension, their caregivers, and 35 healthcare professionals from a Nigerian hospital. The 27-item FFQ was found to be easy to complete, […] ➡️➡️➡️

“`html Analysis of Antenatal Corticosteroid Prophylaxis Effectiveness Objective: Examine trends in effective antenatal corticosteroid prophylaxis (ACS) use for preterm birth-related diagnoses. Methods: Retrospective study using delivery data at Charité Berlin, Germany from 2014 to 2020. Evaluate the rate of effective ACS administrations (≤10 days before delivery) and the percentage of post-ACS deliveries at or after […] ➡️➡️➡️

“`html Telemedicine Program for Glaucoma Monitoring Key Findings: Glaucoma affects around 70 million people globally and is expected to impact up to 112 million by 2040. A telemedicine program was implemented to monitor glaucoma and glaucoma suspect patients during the COVID-19 pandemic. 11,034 telemedicine consults were conducted, with a high adherence rate of 99.8%. 49% […] ➡️➡️➡️

“`html Obstructive Sleep Apnea (OSA) and the Role of Telemedicine in CPAP Treatment Introduction: Obstructive sleep apnea (OSA) is a common sleep disorder linked to cardiovascular risk and daytime sleepiness. Continuous positive airway pressure (CPAP) is a treatment that keeps the airway open. Telemedicine in CPAP devices provides an alternative way for clinical staff to […] ➡️➡️➡️