Clinical trials

Background Detecting tuberculosis (TB) cases is crucial for controlling the disease, especially in countries like Ethiopia where TB is common. This study looked at combining traditional and modern TB care to improve detection rates. Study Overview A trial took place from February 2023 to January 2024 in six districts of South Gondar Zone, Northwest Ethiopia. […] ➡️➡️➡️

Background High blood pressure, or hypertension, is a major health risk for heart diseases. Most people with hypertension live in low- and middle-income countries. This study focuses on a traditional Ayurvedic treatment called Sarpagandha Mishran to see how well it works for managing Stage-I hypertension. Study Method This clinical trial is designed to be very […] ➡️➡️➡️

“`html Background Patients with chronic low back pain (CLBP) often struggle with poor posture due to weak core muscles. Dynamic neuromuscular stabilization (DNS) uses techniques based on how infants move to help improve muscle function. While DNS has helped improve posture in other conditions, it’s unclear if it works better for CLBP patients compared to […] ➡️➡️➡️

Overview of the Study This study focuses on patients with severe brain injuries who may experience disorders of consciousness (DoC) like Unresponsive Wakefulness Syndrome (UWS) and Minimally Conscious State (MCS). The aim is to improve diagnosis and treatment using a method called transcutaneous auricular vagus nerve stimulation (taVNS). Key Findings taVNS can help in identifying […] ➡️➡️➡️

Objective This clinical study looked at how well an experimental pregabalin (PG) gel can reduce dental sensitivity (DS) and color change after teeth whitening. Study Details Seventy-five volunteers participated and were divided into three groups: GPG: 10% pregabalin gel GKF: 5% potassium nitrate and 2% sodium fluoride GP: Placebo gel Before the whitening treatment, the […] ➡️➡️➡️

Study Overview This study examines the effects of using earmuffs on preterm neonates in a Neonatal Intensive Care Unit (NICU). Preterm babies are more sensitive to stress and noise, which can negatively affect their health. Key Findings Noise in NICUs: High noise levels can cause stress and instability in preterm neonates. Recommended Noise Level: The […] ➡️➡️➡️

“`html Study Overview This study focuses on Chronic Spontaneous Urticaria (CSU), a condition that greatly impacts patients’ quality of life. It compares the effectiveness of a treatment combining histaglobulin and antihistamine (bilastine) against using antihistamine alone. Trial Details The trial was conducted at a dermatology outpatient department in a tertiary care hospital from September 2023 […] ➡️➡️➡️

Understanding Postpartum Hemorrhage (PPH) Postpartum hemorrhage is the main reason for maternal deaths after childbirth. It’s important to identify excessive bleeding quickly, but there’s currently no standard method to measure it effectively. A Study on Measuring Blood Loss We conducted a study to compare two different methods of measuring blood loss in women who had […] ➡️➡️➡️

Healthcare Results and Solutions Objectives Children with hemiplegia have difficulty moving, especially on one side of their body. This can lead to uneven walking, problems with stability, and weak trunk muscles. This study looked at how a special training program could help improve walking, balance, and trunk strength in these children. Methods Forty children aged […] ➡️➡️➡️

Background The need for therapy is growing, but there aren’t enough therapists available. This study looks at how an AI chatbot named Friend can help people during tough times, especially compared to regular therapy. Methods We conducted a study with 104 women who have anxiety and live in war zones. They were split into two […] ➡️➡️➡️

Understanding PFKFB3 and Its Role in Breast Cancer Treatment Background Research shows that higher levels of a protein called PFKFB3 can be found in several types of cancer. This protein helps cancer cells to survive radiation therapy. The SweBCG91RT trial looked at whether measuring PFKFB3 could help predict how well breast cancer patients respond to […] ➡️➡️➡️

Background The study focused on a drug called asciminib for patients with chronic myeloid leukemia (CML) in the chronic phase. The goal was to improve how we understand the drug’s effects in different patient groups and ensure it works effectively and safely. Methods Researchers used data from various studies involving patients with different stages of […] ➡️➡️➡️

Background Music can help reduce anxiety for patients before surgery. However, we didn’t know how long the music should be played to be effective. This study aimed to find out how long different types of music need to be played to help calm pregnant women waiting for cesarean delivery. Methodology We conducted a study where […] ➡️➡️➡️

Study Overview This study looked at the effects of arimoclomol on muscle health in people with inclusion body myositis (IBM) using advanced imaging techniques called quantitative magnetic resonance imaging (qMRI). The goal was to see if qMRI could be a useful tool in tracking treatment outcomes. Study Design Eighteen participants were involved in this study, […] ➡️➡️➡️

Background There is a strong need to help patients with inherited cancer risks and their family members. Engaging these patients can help their families understand genetic risks better. The Genetic Information and Family Testing (GIFT) Study aims to support patients with inherited cancer risks and assist their relatives in starting genetic risk evaluations, including home […] ➡️➡️➡️

Study Overview This study focused on how peer group management can help people with chronic pain, especially those who struggle to work due to their condition. It explored whether group support could provide relief when traditional treatments fall short. Who Participated? The participants were employees aged 18-65 from the Municipality of Helsinki, mostly women (83%). […] ➡️➡️➡️

Background Postural orthostatic tachycardia syndrome (POTS) causes symptoms like dizziness and rapid heartbeat when standing up. It is often seen in people recovering from COVID-19. Study Purpose This study aimed to test if low-level tragus stimulation (LL-TS) could help patients with POTS after COVID-19. Study Details We included 57 participants who had POTS after COVID-19. […] ➡️➡️➡️

Importance of Cognitive Behavioral Therapy for Insomnia (CBT-I) CBT-I can help reduce symptoms of depression, but we need to understand how it works better. Study Objective The goal of this study was to see if CBT-I changes the way people perceive emotions in facial expressions and if these changes help improve depressive symptoms. Study Design […] ➡️➡️➡️

Introduction Patients in COVID-19 intensive care units often face psychological challenges like anxiety and depression. These issues can hinder their recovery. This study looks at how a supportive training program can help reduce these symptoms in hospitalized patients. Study Overview In 2021, a study was conducted with 60 COVID-19 patients in Najaf hospitals. Patients were […] ➡️➡️➡️

Background Breast cancer is the most common cancer among women globally, with triple-negative breast cancer (TNBC) being the most aggressive type. In India, TNBC makes up about one-third of all breast cancer cases. While adding pembrolizumab to standard chemotherapy has shown benefits, many patients in low- and middle-income countries cannot access this treatment due to […] ➡️➡️➡️