Clinical trials

Research Findings on Trigger Warnings A recent study examined the effectiveness of trigger warnings for emotionally challenging content. It found that both traditional and modified trigger warnings do not significantly reduce distress in individuals, including those who may be more vulnerable due to anxiety or trauma. Study Overview The study involved 606 university students who […] ➡️➡️➡️

Introduction Oligodendroglioma (ODG) is a rare brain tumor that mostly affects younger adults. Treatment usually involves surgery, radiation therapy (RT), and chemotherapy. However, traditional RT can lead to long-term problems with thinking and quality of life. Proton beam therapy (PBT) may offer a better option by reducing radiation exposure to healthy brain tissue. Study Overview […] ➡️➡️➡️

Study Overview This study looked at the effects of aspirin and omega-3 fatty acids (FAs) on age-related macular degeneration (AMD), a major eye condition affecting older adults. It was part of a larger trial aimed at understanding heart health in people with diabetes. Research Purpose The goal was to determine if aspirin and omega-3 FAs […] ➡️➡️➡️

Background There are not many approved treatments for aggression and agitation in dementia patients. Although antipsychotics and benzodiazepines are often used, they can have serious side effects. Weighted blankets may offer a non-drug option to help reduce agitation in these patients. Objective This study aims to explore how weighted blankets affect aggression and agitation in […] ➡️➡️➡️

Background Acute kidney injury (AKI) can lead to serious health problems and high medical costs. An electronic alert system was created to help doctors diagnose AKI more effectively by automatically collecting important information and sending alerts. However, we still need to understand how this system affects medical expenses. Methods This study analyzed data from a […] ➡️➡️➡️

“`html Importance of Ultrasound Neuromodulation in Alzheimer’s Disease As dementia cases rise and treatment options remain limited, ultrasound neuromodulation presents a new potential therapy for Alzheimer’s Disease (AD). More research is needed to understand its full capabilities in treating brain disorders. Study Overview This study evaluated the effects of transcranial pulse stimulation (TPS) on patients […] ➡️➡️➡️

“`html Importance of Emergency Departments for Children’s Mental Health The emergency department (ED) plays a crucial role in helping children facing mental and behavioral health crises. It acts as a central point for families looking for support. Study Objectives This study aimed to assess the effects of a new mental health care approach on children’s […] ➡️➡️➡️

“`html Objective The study aimed to understand how the order of treatment—using stimulant medication and behavioral parent training—affects outcomes for children and mothers in families with multiple cases of attention-deficit/hyperactivity disorder (ADHD). Methods Mothers with ADHD and their children showing high ADHD symptoms participated in the study. Thirty-five mother-child pairs were randomly assigned to four […] ➡️➡️➡️

“`html Background and Objectives Chronic pelvic pain (CPP) is a common issue linked to pelvic inflammatory disease (PID). While acupuncture is often used to manage CPP, there hasn’t been enough research on using laser stimulation at specific acupuncture points. This study aimed to explore how laser treatment affects pain and quality of life in women […] ➡️➡️➡️

“`html Background and Objectives Fibromyalgia (FM) causes widespread chronic pain, stiffness, sleep issues, and fatigue. This study aimed to compare two recovery methods for improving sleep quality: a standard treatment in a hospital versus a relaxation therapy at home. Materials and Methods The study involved 60 adult patients diagnosed with FM. They were divided into […] ➡️➡️➡️

“`html Background and Objectives Prediabetes is a condition where blood sugar levels are higher than normal but not high enough to be classified as diabetes. This study looked at how a structured exercise program could improve health markers in inactive people with prediabetes over 16 weeks. Study Overview A 16-week randomized controlled trial was conducted […] ➡️➡️➡️

“`html Background and Objectives Clostridioides difficile infection (CDI) is a serious type of diarrhea often acquired in hospitals. This study looked at how the probiotic Bacillus licheniformis (B. licheniformis) can help maintain healthy gut bacteria in patients with CDI. Study Overview This research was conducted at six academic centers in Korea. It involved patients diagnosed […] ➡️➡️➡️

“`html Nutrients Study on Dysmenorrhea Dysmenorrhea is a condition that causes pain during menstruation and affects many women. This study looked at how probiotics and high-intensity interval training (HIIT) can help reduce the severity of dysmenorrhea. Study Overview Participants were divided into groups based on their condition: Control Group: No dysmenorrhea Dysmenorrhea Group: Experiencing dysmenorrhea […] ➡️➡️➡️

“`html Understanding Paroxysmal Sympathetic Hyperexcitation (PSH) Paroxysmal sympathetic hyperexcitation (PSH) is a condition that occurs after severe brain injuries, leading to sudden increases in sympathetic nervous system activity. This study explores how effective a treatment combining transcranial direct current stimulation (tDCS) and medication can be for PSH patients. Study Overview In this study, 40 patients […] ➡️➡️➡️

“`html Understanding Autism Spectrum Disorder (ASD) ASD is a condition that affects social interaction and can lead to repetitive behaviors. There is a need for new therapies that specifically target these behaviors. Study Overview This study investigates whether high-definition transcranial direct current stimulation (HD-tDCS) can help reduce these repetitive behaviors in children with ASD. It […] ➡️➡️➡️

“`html Clinical Trial Overview This study compared two methods for diagnosing chronic coronary syndrome (CCS) in patients experiencing chest pain. The methods were: Coronary Computed Tomographic Angiography (CCTA) followed by Invasive Coronary Angiography (ICA) Direct Invasive Coronary Angiography (ICA) Study Design A total of 1200 patients were included from TEDA International Cardiovascular Hospital between January […] ➡️➡️➡️

“`html Study Overview This study looks at how negative pressure wound therapy (NPWT) affects a small molecule called microRNA-155 (miR-155) in patients with diabetic foot ulcers (DFUs) and how this relates to wound healing. What We Did We involved 60 patients with DFUs, dividing them into two groups: one group received NPWT (40 patients) and […] ➡️➡️➡️

“`html Introduction Delirium is a common and serious condition in older patients in hospitals. It can lead to higher death rates, longer stays in the hospital, and problems with thinking. Researchers are looking into whether melatonin can help prevent delirium by improving sleep and regulating body rhythms. This study will see how well melatonin works […] ➡️➡️➡️

Background HIV transmission has risen in the U.S. among people who inject drugs. Testing for HIV and connecting individuals to treatment is essential for both personal and public health. However, many barriers prevent access to testing, even within programs designed to support this population. Study Overview This study will evaluate a new approach to improve […] ➡️➡️➡️

Objective: Vonoprazan is a new medication that helps treat Helicobacter pylori infections effectively. This study compares a 14-day treatment with vonoprazan and amoxicillin against personalized therapy based on drug sensitivity. Methods: In this study, 240 adults who did not respond to previous H. pylori treatments were randomly assigned to either the vonoprazan-amoxicillin treatment or the […] ➡️➡️➡️