Clinical trials

Understanding the Trial Results The study looked at using a probiotic called Saccharomyces boulardii along with the antibiotic vancomycin to treat Clostridioides difficile infection (CDI). Here’s what we found: What Worked: The combination of S. boulardii and vancomycin showed a higher overall cure rate and reduced the chances of the infection coming back. What Didn’t […] ➡️➡️➡️

Understanding the Trial Results The study looked at whether using a preoperative enema before anal surgery helps patients. Here’s what we found: What Worked? For most patients, using a preoperative enema did not make a difference in pain levels or complications after surgery. Patients who had a specific type of surgery (Milligan-Morgan haemorrhoidectomy) reported less […] ➡️➡️➡️

Understanding the Study Results This study looked at different ways to treat melasma, a common skin condition. Melasma can be hard to treat because existing treatments often have side effects and don’t always work well. The researchers tested a new form of tranexamic acid (TXA) using nanotechnology, which helps the medicine penetrate the skin better. […] ➡️➡️➡️

Understanding the Trial Results What Worked? Pramipexole showed some improvement in reducing depressive symptoms in patients with treatment-resistant bipolar depression. Positive effects were noted on mood and psychosocial function over time. Patients experienced improvements in quality of life and well-being. What Didn’t Work? The difference in effectiveness between pramipexole and a placebo was not statistically […] ➡️➡️➡️

Trial Results Explained The study looked at how well a new type of nutrition, called LEOVIT ONCO, helps patients with esophageal and gastric cancer who are not getting enough protein and energy. Here’s what they found: What Worked: Patients who used LEOVIT ONCO showed better improvements in their body weight and protein levels compared to […] ➡️➡️➡️

Understanding the Trial Results The study looked at how effective cardiac rehabilitation is for patients who have had an acute coronary syndrome (ACS), which is a serious heart condition. Here’s what they found: What Worked Patients in the cardiac rehabilitation program followed dietary guidelines better (73.5% vs. 52.4%). They were more active physically (85.3% vs. […] ➡️➡️➡️

Understanding the Trial Results The PREVENTOMICS study looked at how effective personalized nutrition plans are for adults with overweight and obesity in Poland and the UK. Here’s what we found: What Worked? Personalized nutrition plans combined with behavioral changes (PP+B) showed potential for cost-effectiveness in Poland and the UK. Both PP+B and personalized plans (PP) […] ➡️➡️➡️

Summary of the Trial Results This study looked at how different ways of informing Latina women about their breast density after a mammogram affected their feelings about breast cancer. The research included three methods of communication: regular mail, mail with extra educational materials, and one-on-one support from a community health worker. What Worked? None of […] ➡️➡️➡️

Understanding the Trial Results This study looked at factors that can predict how successful rapid maxillary expansion (RME) will be in late adolescents. Here’s what the results mean: What Worked? Patients with higher maturity stages of the midpalatal suture (MSM) and cervical vertebrae (CVM) had a higher chance of RME failure. Patients with a lower […] ➡️➡️➡️

Understanding the Trial Results The study looked at two ways to help children who have a cardiac arrest outside of a hospital. One method used a device called i-gel® for airway management, while the other used a bag-valve-mask. Here’s what we found: What Worked: Both methods provided similar levels of ventilation, meaning they both helped […] ➡️➡️➡️

Understanding the Study Results This study looked at how certain personality traits affect how women cope with breast cancer. The main focus was on: Self-Criticism: Being hard on oneself. Dependency: Relying on others for support. Efficacy: Feeling capable and effective. The results showed that: Women who were more self-critical had a harder time functioning, felt […] ➡️➡️➡️

Understanding the Trial Results This study looked at how the position of a patient’s arms during a special type of scan—used for checking blood vessels in the neck and chest—affected the quality of the images and the amount of radiation exposure. Here’s what we found: What Worked: Keeping both arms down by the sides of […] ➡️➡️➡️

Understanding the Study Results The study focused on helping adolescent girls manage the emotional challenges of Premenstrual Syndrome (PMS). The key findings are: What Worked: The therapy program combining Cognitive Behavioral Therapy (CBT) and Narrative Therapy significantly reduced negative thinking and emotional distress related to PMS. What Didn’t Work: There were no notable negative outcomes […] ➡️➡️➡️

Results of the Spiritual Care Program The study found that a spiritual care program significantly helped mothers of children with leukemia. Here’s what worked: Increased Self-Efficacy: Mothers who participated in the program felt more confident in their caregiving abilities. Reduced Caregiver Burden: These mothers reported feeling less overwhelmed and stressed after the program. On the […] ➡️➡️➡️

Understanding the Trial Results This study looked at how body composition affects patients with heart failure who have preserved ejection fraction (HFpEF). Here’s what we found: What Worked? Higher fat mass index (FMI) was linked to a greater risk of serious health issues and death. Higher lean body mass index (LBMI) was associated with a […] ➡️➡️➡️

Understanding the Trial Results This study looked at how to help patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) use their CPAP machines better. The trial compared two groups: one received extra education and support, while the other got standard care. What Worked? Patients who received therapeutic patient education (TPE) and augmented clinical support (ACS) were […] ➡️➡️➡️

Understanding the Trial Results The study looked at how well injectable buprenorphine (LAB) helps people with opioid use disorder (OUD) who are hospitalized with infections. The main goal was to see if starting LAB during their hospital stay would lead to more patients receiving medication for OUD after 12 weeks compared to standard treatment. What […] ➡️➡️➡️

Findings from the Atorvastatin Trial for Kawasaki Disease What Worked? The trial showed that atorvastatin is safe for Japanese children with acute Kawasaki disease (KD) and coronary artery aneurysms (CAAs). The maximum dose that was well-tolerated was 0.5 mg/kg per day for six weeks. There were no serious harmful effects, and any minor liver enzyme […] ➡️➡️➡️

Understanding the Trial Results This clinical trial is exploring how a traditional treatment, called Rasayana Formulation (RF) along with Shigru Pallava eye drops, can help people with Primary Open-Angle Glaucoma (POAG). The goal is to see if these treatments can protect the eyes and lower eye pressure better than standard care alone. What Worked? If […] ➡️➡️➡️

Understanding the Trial Results This study looked at a new treatment for children with autism spectrum disorder (ASD). It tested whether giving children their own stem cells from bone marrow, along with educational support, would help them more than just education alone. What Worked? The group that received stem cell therapy and education showed a […] ➡️➡️➡️