Smart Healthcare

Itinai.com light and shadow chase in a bright clinical trial 94e57646 2deb 4898 b35d 841dc91eb7a5 3

Itinai.com light and shadow chase in a bright clinical trial 94e57646 2deb 4898 b35d 841dc91eb7a5 3

Current updates relating to treatment for interstitial cystitis/bladder pain syndrome: systematic review and network meta-analysis

Current updates relating to treatment for interstitial cystitis/bladder pain syndrome: systematic review and network meta-analysis

“`html

Study Summary: Efficacy of Therapies for Interstitial Cystitis (IC) / Bladder Pain Syndrome (BPS)

Background

Despite previous studies, there is no complete review of treatment options for IC/BPS. This study aimed to assess the effectiveness of different therapies and identify factors that influence their success.

Methods

Reviewed 70 trials with 3,651 patients
Looked at symptoms like pain, urgency, frequency, and nocturia
Used meta-analysis to compare treatments

Results

Certain treatments like instillation and intravesical injection showed significant improvements in pain and urgency. No single treatment showed significant improvement in all symptoms. Age and follow-up period were found to influence specific symptoms.

Conclusion

Combining therapies may be beneficial for IC patients, even though treatment is challenging. The study provides valuable insights into the effectiveness of IC treatments.

TRIAL REGISTRATION: PROSPERO CRD42022384024

“`

2024-04-25

Clinical trials

AI-Powered Health Tools

Interactive AI Tools to Help You Understand Your Health

Solutions for Smart Healthcare

Clinical Research

2025-01-11

Clinical trials

Comparison of diaphragmatic breathing exercises and incentive spirometry on the functional status of heart failure patients: a randomized controlled trial

Comparison of Breathing Exercises and Incentive Spirometry for Heart Failure Patients Background Heart failure (HF) can weaken respiratory muscles, leading to symptoms like fatigue and shortness of breath. Strengthening these…
2025-04-24

Clinical trials

The longitudinal impact of low-dose morphine on diurnal cortisol profiles in people with chronic breathlessness and chronic obstructive pulmonary disease (COPD): an exploratory study

Study Overview This study explored how low-dose morphine affects cortisol levels and breathlessness in people with chronic obstructive pulmonary disease (COPD). Cortisol is a hormone linked to stress, and understanding…
2025-02-27

Clinical trials

Weighted Blankets for Agitation in Hospitalized Patients with Dementia: Protocol for a Randomized Controlled Trial

Background There are not many approved treatments for aggression and agitation in dementia patients. Although antipsychotics and benzodiazepines are often used, they can have serious side effects. Weighted blankets may…
2024-05-24

Clinical trials

Early diagnosis of melanoma: a randomized trial assessing the impact of the transmission of photographs taken with a smartphone from the general practitioner to the dermatologist on the time to dermatological consultation

Early Diagnosis of Melanoma: Impact of Smartphone Photo Transmission on Dermatological Consultation Time Background: Difficulty in obtaining timely dermatological consultation hinders early melanoma diagnosis. Optimizing patient care pathways is crucial…
2025-05-12

Clinical trials

Effects of Tai Chi and Qigong intervention on anxiety and stress in diabetic and hypertensive Brazilian patients: a randomized controlled trial

Study Overview This study looked at how practicing Tai Chi and Qigong for 13 weeks affects anxiety and stress in middle-aged and older Brazilian patients with diabetes and high blood…
2024-06-23

Clinical trials

Association of demographics, lumbar active range of motion and disability in chronic low back: a baseline data analysis of a randomized controlled trial from Pakistan

Association of Demographics, Lumbar Range of Motion, and Disability in Chronic Low Back: Baseline Data Analysis BMC Musculoskelet Disord. 2024 Jun 22;25(1):489. doi: 10.1186/s12891-024-07613-9. Background: Low back pain (LBP) poses…
2025-04-14

Clinical trials

Evaluation of a novel elbow joint torque measurement device in healthy subjects and stroke patients: a randomized trial

Introduction Current clinical practice struggles to measure elbow joint movements effectively. This study introduces a new device called the Elbow Joint Torque Measurement Device (EJTMD) that measures muscle strength and…
2025-03-20

Clinical trials

Inadequate consumption of dietary fatty acids is a risk factor for ovarian cancer: evidence from the prostate, lung, colorectal, and ovarian cancer screening trial

Understanding the Link Between Dietary Fatty Acids and Ovarian Cancer Purpose: There is ongoing debate about how dietary fatty acids (FAs) may affect the risk of ovarian cancer (OC). This…
2025-05-27

Clinical trials

Single-Dose IncobotulinumtoxinA: A Promising Pain Relief for Early Knee Osteoarthritis

Understanding the Trial Results This study looked at a treatment for early-stage knee osteoarthritis (OA), a common condition that causes pain and disability. The researchers tested a single dose of…
2025-04-24

Clinical trials

Effect of Upper Body Flexibility Exercises on Respiratory Muscle Performance, Upper Limb Endurance and Activities of Daily Living in Patients With Chronic Respiratory Disease-A Randomized Control Trial

Background and Purpose Patients with chronic respiratory disease (CRD) often use their neck muscles for breathing, which can lead to poor posture and reduced muscle efficiency. Improving upper body flexibility…
2024-08-20

Clinical trials

Multivitamin Compliance Reduces Injuries of Female Recruits at Air Force Basic Training: A Randomized Controlled Cohort Study

Multivitamin Compliance Reduces Injuries of Female Recruits at Air Force Basic Training: A Randomized Controlled Cohort Study ABSTRACT Introduction: Basic military training (BMT) for U.S. Air Force and Space Force…
2025-01-14

Clinical trials

A phase II double-blind multicentre, placebo-controlled trial to assess the efficacy and safety of alpelisib (BYL719) in paediatric and adult patients with Megalencephaly-CApillary malformation Polymicrogyria syndrome (MCAP): the SESAM study protocol

A Phase II Clinical Trial for MCAP Syndrome: The SESAM Study Introduction Megalencephaly capillary malformation polymicrogyria (MCAP syndrome) is caused by specific genetic changes. Key symptoms include large head size,…
2025-04-21

Clinical trials

Improving and preserving cardiorespiratory fitness, muscle strength and adiposity through a complex lifestyle intervention in community-dwelling older adults with elevated cardiometabolic risk: study protocol for the RESTART randomised controlled trial

Introduction As people age, they face more health issues related to heart and metabolism, which can increase healthcare costs. To help older adults maintain their physical health, the RESTART trial…
2025-01-29

Clinical trials

Minimally invasive compared to open surgery in patients with low-risk cervical cancer following simple hysterectomy: An exploratory analysis from the Gynegologic Cancer Intergroup/Canadian Cancer Trials Group CX.5/SHAPE trial

Minimally Invasive Surgery for Low-Risk Cervical Cancer Study Overview This study examines whether minimally invasive surgery (MIS) is safe for women with low-risk cervical cancer who have undergone simple hysterectomy.…
2025-04-22

Clinical trials

Electrical Muscle Stimulation With or Without Blood Flow Restriction Does Not Prevent the Impairment in Glycemic Control After 1 Week of Physical Inactivity

Summary of Research Findings Physical inactivity can harm blood sugar control, but exercise can help. This study looked at whether using electrical muscle stimulation (EMS) with or without blood flow…