Effects of Synbiotic Supplementation on Bone and Metabolic Health in Caucasian Postmenopausal Women: Rationale and Design of the OsteoPreP Trial

Effects of Synbiotic Supplementation on Bone and Metabolic Health in Postmenopausal Women

Overview

This study explores how a synbiotic supplement can help improve bone and metabolic health in Caucasian postmenopausal women. The OsteoPreP trial will last for 12 months and aims to see if this supplement can prevent bone loss and improve overall health.

Study Details

The trial involves 160 postmenopausal women who do not have osteoporosis or are not currently taking any bone-affecting treatments. Participants will undergo scans to ensure they do not have osteoporosis before starting the trial.

Key Goals

  • Primary Goal: Measure the change in bone density in the tibia after 12 months.
  • Secondary Goals: Assess effects on the immune system, cognition, gut health, and blood sugar levels.

Importance of the Trial

This trial will provide valuable information on the safety and effectiveness of a synbiotic supplement that includes both types of bacteria and prebiotic fiber. The findings could lead to new strategies for preventing osteoporosis and managing metabolic issues in postmenopausal women.

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