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Improving Gait and Reducing Falls in Older Adults with Mild Cognitive Impairment: Insights from the SYNERGIC Trial

Understanding the SYNERGIC Trial Results

The SYNERGIC trial looked at how combining exercise, cognitive training, and vitamin D affects walking and the risk of falling in older adults with mild cognitive impairment (MCI). Here’s what the results mean for patients and clinics.

What Worked?

  • Exercise and Cognitive Training: Participants who did aerobic-resistance exercises along with cognitive training improved their walking speed by 7.5 cm/s in just 6 months.
  • Reduced Falls: There was a significant drop in falls and serious falls after 12 months for those who participated in the exercise and training program.

What Didn’t Work?

  • Vitamin D Supplementation: Adding vitamin D did not help improve walking or reduce falls. In fact, it made walking less stable for some.

How Does This Help Patients and Clinics?

These findings suggest that older adults with MCI can benefit from a combination of exercise and cognitive training to improve their mobility and reduce the risk of falls. Clinics can use this information to design better programs for their patients.

Real-World Opportunities

  • Hospitals can create exercise and cognitive training programs tailored for older adults with MCI.
  • Doctors can recommend specific exercises and cognitive activities to help improve gait and reduce falls.

Measurable Outcomes to Track

  • Walking speed improvements (measured in cm/s).
  • Number of falls and serious falls recorded.
  • Patient feedback on mobility and confidence in walking.

AI Tools to Consider

Clinics can explore AI solutions to track patient progress and customize exercise plans. For example, AI apps can monitor walking speed and provide reminders for exercises.

Step-by-Step Plan for Clinics

  1. Start Small: Begin with a pilot program that includes simple aerobic-resistance exercises and basic cognitive training.
  2. Gather Feedback: Collect data on patient progress and experiences after a few months.
  3. Adjust Programs: Use the feedback to improve and expand the program based on what works best.
  4. Educate Staff: Train healthcare providers on the importance of exercise and cognitive training for older adults with MCI.

For more details on the research, you can read the full study here.

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