Pilot Study on Direct MRCP for Gallstone Assessment
Background
Patients suspected of having gallstones usually get an abdominal ultrasound. However, if liver function tests (LFTs) are abnormal, they often undergo MRCP instead. This study explores whether MRCP can replace ultrasound, especially since new AI technologies may improve the accuracy of MRCP readings.
Method
Patients with suspected gallstone disease and abnormal LFTs were divided into two groups: one received direct MRCP, while the other followed standard care. We collected data on hospital visits, costs, and health outcomes. We also analyzed MRCP scans using specialized software.
Results
A total of 27 patients participated in the study over 12 months. The direct MRCP group had a quicker diagnosis, averaging 2.53 days and costing £449.54, compared to 4.18 days and £742.06 for standard care. The MRCP analysis revealed significant differences in gallbladder volume and cystic duct width between the two groups, indicating that direct MRCP may be more effective.
Conclusions
Direct MRCP appears to be a promising and cost-effective option for diagnosing suspected gallstone disease in patients with abnormal LFTs. The use of automated measurements could enhance detection of blockages. Further research with larger trials is needed to confirm these findings.
Clinical Trial Registration
This study is registered on ClinicalTrials.gov (NCT03709030) since October 17, 2018.
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