Relationship between electronically monitored adherence to direct oral anticoagulants and ischemic or hemorrhagic events after an initial ischemic stroke-A case control study

“`html

Study Overview

Patients with atrial fibrillation (AF) who have had an ischemic stroke are at high risk for further clinical events. Taking direct oral anticoagulants (DOAC) is important for preventing these events, but some patients may not take their medication as prescribed. This study looked at how well stroke survivors with AF adhered to their DOAC treatment.

Practical Solutions

• Using a small electronic device (Time4MedTM) to measure DOAC intake
• Defining specific time intervals for monitoring adherence
• Retrospective calculation of adherence to DOAC
• Adjusting for age and daily pill burden in the analysis

Key Findings

• Adherence to DOAC was high overall, but varied for different types of clinical events
• Low adherence (<76%) was associated with recurrent ischemic events
• High adherence (>96%) was associated with hemorrhagic complications

Value

Improving adherence to DOAC in AF patients could help prevent recurrent ischemic events. However, patients with high adherence should also be regularly assessed for bleeding risk.

For more information, visit ClinicalTrials.gov

“`

Full Clinical Trial Report Relationship between electronically monitored adherence to direct oral anticoagulants and ischemic or hemorrhagic events after an initial ischemic stroke-A case control study: https://pubmed.ncbi.nlm.nih.gov/38662779/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=1B1L42DK3a-JWCV4P_PtHHBmWjwBLFNcDXsYJkbqjQD0Ca7UQh&fc=None&ff=20240425230036&v=2.18.0.post9+e462414