Clinical Trials

“`html Background Infections from wounds can be tough to treat, especially with bacteria becoming resistant to common antibiotics. This highlights the need for new treatment methods that are proven effective through reliable testing. Objective This study aimed to evaluate how well phage therapy works compared to traditional treatments for patients with various types of surgical […] ➡️➡️➡️

Background The iCAN mobile health program aims to help people experiencing homelessness by improving their access to healthcare and reducing visits to hospitals and emergency rooms. Objective This study evaluates the costs and financial benefits of the iCAN program through three main analyses: cost analysis, cost-benefit analysis, and budget impact analysis. Methods We gathered financial […] ➡️➡️➡️

Background Patients with a high risk of bleeding often have complicated heart artery issues. This study looked at whether using advanced imaging during heart procedures (called PCI) helps these patients more than traditional imaging methods. Study Overview This research was part of a larger trial called RENOVATE-COMPLEX-PCI, which took place in Korea from May 2018 […] ➡️➡️➡️

Overview of the Clinical Trial A recent clinical trial in Japan explored the use of rituximab, a treatment for membranous nephropathy with nephrotic syndrome, without steroids or immunosuppressants. This study involved 88 patients and compared the effects of rituximab against a placebo. Study Design This was a multicenter trial, taking place at 15 locations in […] ➡️➡️➡️

Aim of the Study This study aimed to compare the effectiveness of using laser treatment combined with sinus curettage against using curettage alone for treating pilonidal sinus disease (PSD). We looked at postoperative complications, how well wounds healed, and the chances of the disease coming back. We also wanted to find out what factors might […] ➡️➡️➡️

Study Overview This study looked at how adults with higher body weights face weight stigma in healthcare settings and how a specific strategy can help. The strategy involves using an “identity-safety cue,” which shows that a person’s social identity is valued. Study Details A total of 527 adults in the U.S. who identified as overweight […] ➡️➡️➡️

“`html Importance of Colorectal Cancer Screening About 60 million adults live in rural areas of the US, where many do not get screened for colorectal cancer (CRC). This is especially true for those on Medicaid. Study Objective The goal of this study was to see how effective a program was that used mailed tests and […] ➡️➡️➡️

Background Immune checkpoint blockade (ICB) is a treatment that works well for some patients with head and neck squamous cell carcinoma (HNSCC), but many do not respond to it. Study Overview In a recent clinical trial, patients with recurrent or metastatic HNSCC who did not respond to ICB were given a low dose of a […] ➡️➡️➡️

Understanding Insulin Resistance in Adolescents This study looks at how insulin resistance (IR) affects teenagers with obesity, especially focusing on fat tissue in their bodies. Key Findings Researchers tested 30 teenagers, some with IR and others without it, using a glucose test and MRI scans. They found: Teenagers with IR had a harder time controlling […] ➡️➡️➡️

Vitamin D₃ for Tic Disorders in Children Background Vitamin D₃ might help reduce tic symptoms in children with chronic tic disorders (CTDs). This study looked at how different doses of vitamin D₃ affect tic severity and vitamin D levels in kids diagnosed with CTDs. Study Overview In the study, 83 children aged 4 to 15 […] ➡️➡️➡️

Comparison of Ticagrelor and Clopidogrel This study looked at how well Ticagrelor and Clopidogrel work for patients with coronary heart disease and unstable angina. The goal was to understand their effects on heart health and inflammation. Key Findings The Ticagrelor group had fewer angina attacks compared to the Clopidogrel group. Patients taking Ticagrelor experienced shorter […] ➡️➡️➡️

Background Chronic Plantar Fasciitis (CPF) is a condition that causes persistent foot pain and is often linked with anxiety and fear of movement. An approach called Pain Neuroscience Education (PNE) has shown potential in helping with these mental aspects, but there hasn’t been enough strong evidence on how well it works when combined with physiotherapy […] ➡️➡️➡️

Psychological Support for Cancer Patients This study focused on helping cancer patients who struggle with adjustment disorders through a special psychological program. Here’s what we found: Study Overview We looked at 59 cancer patients, dividing them into two groups: one received the psychological support program, and the other did not. The program included: Psychoeducation: 1-4 […] ➡️➡️➡️

Understanding Egg Allergy Prevention in Infants Key Findings from Recent Research Egg allergy (EA) is a common issue among children, alongside cow’s milk allergy and atopic dermatitis. This study highlights the benefits of introducing baked eggs into an infant’s diet early on. By starting baked egg consumption between 4 to 6 months of age and […] ➡️➡️➡️

Background Functional dyspepsia (FD) is a common reason people visit doctors. It can lead to high medical costs and impact patients’ quality of life. This study looked at how meditation can help people with FD when used alongside standard treatments. Meditation is a safe and affordable therapy that may reduce the side effects of long-term […] ➡️➡️➡️

Background The study explored how adding methylene blue to a pain relief method called fascia iliaca compartment block (FICB) could improve pain management after hip surgery. Study Overview Ninety elderly patients scheduled for total hip arthroplasty (THA) participated in this clinical trial from June 2023 to February 2024. They were divided into two groups: MB […] ➡️➡️➡️

Study Overview This study explored how low-calorie diets can help Chinese individuals with type 2 diabetes (T2D) achieve remission. Unlike other ethnic groups, Chinese people have unique characteristics related to T2D and obesity. The goal was to see if a low-calorie formula diet (LCFD) or a low-calorie real food-based diet (LCRFD) could be effective for […] ➡️➡️➡️

Study Overview This study focused on finding the right dose of ciprofol, used with sufentanil, to safely sedate patients during gastroscopy procedures. Aim of the Study The goal was to identify the dose of ciprofol that effectively sedates 90% of patients when combined with 5 µg of sufentanil. Study Method This was a double-blind study […] ➡️➡️➡️

Background High-sensitive cardiac troponin tests help predict outcomes for patients with atrial fibrillation (AF). However, there is limited research on how long-term treatments affect troponin levels in AF patients without heart disease or heart failure. Study Overview This study, part of the RATe control in Atrial Fibrillation (RATAF) II research, looked at how six months […] ➡️➡️➡️

Background Medical journals recommend specific guidelines for authors to follow when writing their studies. However, many authors find it difficult to choose the right guideline for their work. To help with this, the UK EQUATOR Centre created the GoodReports website. Initial tests showed that simply advising authors to use a guideline did not improve their […] ➡️➡️➡️