Clinical Trials

“`html Understanding AI in Medical Consultations The use of artificial intelligence (AI) in healthcare aims to enhance diagnosis and consultation. However, it’s important to evaluate how this technology affects patients’ experiences and trust. Study Goals This study examines whether AI, or AI combined with human input, can effectively replace human doctors in diagnosis, focusing on: […] ➡️➡️➡️

“`html Improving Access to Hereditary Cancer Risk Assessments Current methods to enhance access to hereditary cancer risk assessments in primary care are insufficient. This study explores two strategies to identify patients with cancer histories and offer genetic testing. Study Overview The EDGE clinical trial involved 12 clinics across Montana, Wyoming, and Washington, engaging a total […] ➡️➡️➡️

Background Acne vulgaris is a common skin condition affecting up to 80% of people aged 11 to 30. It can lead to issues like redness, dark spots, and scarring, which negatively impact quality of life. Topical treatments are commonly used, and sticking to the treatment plan is crucial for success. Aims of the Study This […] ➡️➡️➡️

Background Research shows that screening can encourage people to change their behavior. Low physical activity (PA) is a risk factor for lung cancer that can be changed. This study looks at how safe and practical an 8-week exercise program is for people involved in lung cancer screening. Methods Participants without lung cancer from an Australian […] ➡️➡️➡️

Background Lacrimal irrigation is an important skill for diagnosing and treating eye conditions related to tear drainage. This study looks at two different techniques for lacrimal irrigation and introduces a new self-training model to help new ophthalmology residents learn these skills better. Methods In this study, 92 ophthalmology residents were divided into two groups. Both […] ➡️➡️➡️

“`html Background Diabetic polyneuropathy is a common condition affecting people with diabetes, but there are few proven treatments available. Current options include managing pain, using alpha-lipoic acid, and antidepressants. Some physical therapies, like electrical stimulation and heated stone therapy, have been suggested but lack strong evidence. Study Overview A study was conducted with 68 diabetic […] ➡️➡️➡️

Overview of the Study This study focused on cancer-related fatigue (CRF), a common and troubling issue for cancer patients. Researchers wanted to see if a treatment called 3.95 μm infrared moxibustion could help reduce this fatigue. Study Details A total of 65 cancer patients with CRF participated in a randomized controlled trial. The patients were […] ➡️➡️➡️

Clinical Trial Overview The study published in Lancet Oncology explores the best timing for using nivolumab (a type of PD-1 inhibitor) alongside chemotherapy in patients with early triple-negative breast cancer. The goal was to see how two different schedules of administering nivolumab with carboplatin and paclitaxel (two chemotherapy drugs) would affect treatment outcomes. Study Details […] ➡️➡️➡️

Background Recent research shows that a treatment called stereotactic body radiotherapy (SBRT) can help men with a specific type of prostate cancer that has spread to a few other areas. This study looked at whether adding a short course of hormone therapy (ADT) to SBRT could help patients live longer without their cancer getting worse. […] ➡️➡️➡️

Cognitive Behavioral Therapy for Insomnia in Young Cancer Survivors Background: Many young people who have survived childhood cancer experience insomnia, which can lead to poor health and a lower quality of life. Unfortunately, many do not receive the help they need. An online program called iSleep youth offers cognitive behavioral therapy specifically for insomnia. Study […] ➡️➡️➡️

Overview of Computerized Cognitive Training Computerized cognitive training (cCT) is a treatment that helps people practice mental tasks using a computer. It’s a non-invasive approach, meaning it doesn’t require surgery or other invasive procedures. Unlike traditional face-to-face training, which can be expensive and have long waiting times, mobile cCT is more accessible and flexible for […] ➡️➡️➡️

“`html Study Overview This study explored whether a one-week reduced-carbohydrate diet (RCD) could help improve insulin sensitivity and endothelial function in adults with type 1 diabetes. The researchers compared the effects of the RCD to a standard carbohydrate diet (SCD). Key Findings The RCD led to a 16% reduction in daily insulin doses. However, insulin […] ➡️➡️➡️

Background In cases where scaphoid fractures are suspected but initial x-rays appear normal, patients are usually put in a cast. However, only 10% of these cases actually have a fracture. To prevent unnecessary treatments, we studied whether using a bandage instead of a cast leads to similar recovery results. Study Overview We conducted a clinical […] ➡️➡️➡️

Study Overview Amniocentesis is a common test during pregnancy to check for genetic conditions. This study looked at how using videos to provide information affects anxiety and pain for women undergoing this procedure. Key Findings The study included women aged 18-45 who were scheduled for amniocentesis. They were divided into two groups: one received video-based […] ➡️➡️➡️

Study Overview This study focused on the effectiveness and safety of Cinnatropin®, a biosimilar growth hormone, in treating growth-related disorders in children and adolescents. Key Findings A total of 20,465 patients participated, with 405 in a detailed analysis. The most common issue was growth hormone deficiency. After 12 months, the average height standard deviation score […] ➡️➡️➡️

Background Many traditional antidepressants work well for some patients but not for everyone, especially those with major depressive disorder (MDD). Agomelatine is a different type of antidepressant that may help enhance the effects of standard treatments like SSRIs and SNRIs. This study looks at how well agomelatine works when added to these traditional medications for […] ➡️➡️➡️

Purpose Pathology reports can be difficult for patients newly diagnosed with breast cancer to understand. We studied how patient-centered pathology reports (PCPRs), which use simpler language, can help patients better understand their results. Methods We involved sixty-six patients who were recently diagnosed with breast cancer. They were divided into two groups: one group received both […] ➡️➡️➡️

Study Overview This study aimed to see if probiotics could help improve behavior and gut issues in children aged 2-9 with autism spectrum disorder (ASD). Study Design The research was a single-blinded, randomized, placebo-controlled trial conducted at five clinics. Participants 180 children with ASD participated, divided into two groups: one received probiotics and the other […] ➡️➡️➡️

Study Overview This study looked at how effective a medication called upadacitinib is for patients with axial spondyloarthritis (axSpA), a type of arthritis that affects the spine. The goal was to see if starting treatment early makes a difference in long-term health outcomes. Study Details Researchers conducted two studies (SELECT-AXIS 1 and 2) involving patients […] ➡️➡️➡️

Background People with dementia often have trouble sleeping. The MoNoPol-Sleep study aimed to create and test a new approach to help improve sleep for those living in nursing homes. Objectives The study looked at how well the new sleep intervention was put into practice, what helped or hindered its use, and how it was accepted […] ➡️➡️➡️