Study Title Self-reported menstrual cycle is positively influenced by a well-designed, energy-controlled ketogenic diet compared to a low-fat diet in overweight/obese women of reproductive age Study Information Published in PLoS One on August 16, 2024, this study aimed to compare the effects of a ketogenic diet (KD) and a low-fat diet (LFD) on menstrual patterns…
Suvorexant for Reduction of Delirium in Older Adults After Hospitalization: A Randomized Clinical Trial Objective To evaluate the orexin receptor antagonist suvorexant for reducing delirium in older adults at high risk for delirium after hospitalization. Design and Participants Double-blind, placebo-controlled, phase 3 randomized clinical trial conducted at 50 hospitals in Japan. Study population included Japanese…
The Effect of Promoting Factors on Learning by Four Different Delivery Modes BMC Med Educ. 2024 Aug 15;24(1):880. doi: 10.1186/s12909-024-05864-7. Background: Developing effective teaching methods in the digital era is crucial due to challenges in maintaining students’ concentration. This study assessed the effects of learning-promoting factors across group boundaries and within RCT learning groups, comparing…
EXULTANT Trial: Improving Tuberculosis Diagnosis in HIV-Positive Hospitalized Patients Overview The EXULTANT trial aims to evaluate a new screening strategy for diagnosing tuberculosis (TB) in hospitalized people living with HIV (PLHIV) in Tanzania and Mozambique. The trial focuses on the impact of using multiple specimens (sputum, stool, and urine) for TB diagnosis, along with urine…
Impact of Vojta Therapy on Chronic Lower Back Pain Key Findings: Combining Vojta therapy (VT) with standard care and electrotherapy significantly improved posture, reduced depression, and enhanced self-esteem in patients with chronic lower back pain (LBP). Study Details: A randomized controlled trial involving 148 patients diagnosed with chronic LBP. Patients were split into LBP-VT (n…
Benefits of Home-Based Foot Neuromuscular Electrical Stimulation for Older Adults Introduction Many older adults experience lower leg pain and circulation issues, impacting their daily function and quality of life. This study examined the effects of home-based foot neuromuscular electrical stimulation (NMES) using Revitive® on self-reported function, leg pain, and other leg symptoms. Methods A randomized…
Insomnia prehabilitation in newly diagnosed breast cancer patients: Protocol for a pilot, multicentre, randomised controlled trial comparing nurse delivered sleep restriction therapy to sleep hygiene education (INVEST trial) ABSTRACT Insomnia is a common sleep disorder that affects breast cancer patients, impacting their quality of life. This trial aims to test the feasibility and effectiveness of…
Efficacy and Safety of Shi Cervical Rotational Manipulation in Patients With Atlantoaxial Joint Subluxation: Protocol for a Randomized Controlled Trial ABSTRACT In this study, we aim to evaluate the effectiveness and safety of Shi cervical rotational manipulation (SCRM) in patients diagnosed with atlantoaxial joint subluxation (AJS). SCRM is a traditional Chinese medicine (TCM) manual therapy…
Relative motion splints versus metacarpophalangeal joint blocking splints in the management of trigger finger: Study protocol for a randomized comparative trial ABSTRACT Hand-based metacarpophalangeal joint (MCPJ) blocking splints are commonly used for trigger finger (TF), but finger-based relative motion (RM) splints are also used without evidence. This trial aims to compare the effectiveness, function, occupational…
Exploring the Impact of Environment on Physical Activity in Patients with COPD Practical Solutions and Value Individuals with chronic obstructive pulmonary disease (COPD) often have reduced physical activity levels, which can lead to poorer outcomes. Traditional trials aimed at increasing physical activity have not been very successful. To address this, an ecological model incorporating individual,…
Increasing Cancer Screening Participation Study Overview: A clinical trial investigated the effectiveness of increasing cervical and colorectal cancer screening participation by leveraging attendance at breast cancer screenings. The trial was conducted in the Central Denmark Region from September 2021 to May 2022. Intervention: At selected breast cancer screening units, women attending were offered self-sampling kits…
Online Disease Management Training for Older Adults With Osteoarthritis: A Randomized Controlled Trial Introduction Using online methods in health education is effective for providing individual services to older adults with limited access to health services at low cost, allowing for continuous communication. Methods The study involved 52 older adults diagnosed with osteoarthritis, with 26 in…
Treating Newly Diagnosed Multiple Myeloma with Innovative Therapy Value of the Study A recent study investigated the effectiveness and safety of a new treatment for newly diagnosed multiple myeloma. The treatment, known as the BLD regimen, combined domestic bortezomib with lenalidomide and dexamethasone. The results showed promising outcomes, with a high overall response rate and…
Testing a persuasive health communication intervention (PHCI) for emergency department patients Key Highlights Previous studies have shown that many emergency department (ED) patients in the USA decline HIV or hepatitis C (HCV) testing. We need effective and cost-efficient interventions to increase testing rates, especially for people who inject drugs (PWIDs) who are at higher risk…
Study on FACIT-Fatigue in Axial Spondyloarthritis Patients Key Findings and Practical Solutions Fatigue is a significant symptom for axial spondyloarthritis (axSpA) patients. The FACIT-Fatigue scale, a 13-item patient-reported outcome, was evaluated for its effectiveness in measuring fatigue severity and impact on daily activities in axSpA patients, including those with non-radiographic axSpA (nr-axSpA) and radiographic axSpA…
A Tele-detection and Referral Pathways Model for Early Childhood Caries Control: The TRACE Study Background Early childhood caries (ECC) is a common disease affecting children under 6 years old. It can be reversed in early stages, but often goes undetected. New methods are needed to detect oral diseases early for better control. Methods A randomized…
Role of Comprehensive Vestibular Rehabilitation Based on Virtual Reality Technology in Residual Symptoms After Canalith Repositioning Procedure Abstract Background: This study aimed to investigate the effectiveness of comprehensive vestibular rehabilitation using virtual reality (VR) technology in managing residual symptoms following the canalith repositioning procedure. Methods: 124 patients diagnosed with benign paroxysmal positional vertigo and experiencing…
Comparison of Ultrasound-Guided Adductor Canal Block and Surgeon-Performed Block for Pain Management after Total Knee Arthroplasty: A Prospective Randomized Controlled Study Objective: The study aimed to compare the effectiveness of adductor canal block (ACB) performed by surgeons and anesthesiologists using ultrasound guidance for postoperative pain management after total knee arthroplasty (TKA). Methods: A total of…
Opioid-free Anesthesia vs. Opioid-based Anesthesia in Shoulder Arthroscopy Key Findings: Opioid-free anesthesia (OFA) with esketamine-dexmedetomidine significantly reduced postoperative nausea and vomiting (PONV) compared to opioid-based anesthesia (OBA) with propofol-remifentanil. Patients in the OFA group also experienced shorter post-anesthesia care unit (PACU) stays. Practical Solutions: Implementing OFA with esketamine-dexmedetomidine can help reduce PONV and streamline postoperative…
Efficacy of At-Home Bleaching on Tooth Surfaces Objective To compare the effectiveness and side effects of at-home tooth bleaching on the outer (buccal) surface only versus both the outer and inner (lingual) surfaces. Materials and Methods Sixty patients with certain tooth color were divided into two groups: one received at-home bleaching on the outer surface…