Effective Counseling for Knee Osteoarthritis: A Study Overview Objective This study aimed to see how motivational interviewing-based counseling affects pain, mental health, and self-care in people with knee osteoarthritis. Methods We conducted a randomized controlled trial with 60 participants (29 received counseling, 31 were in the control group). We collected data using: Personal Information Form…
Study Overview This study examines how intravenous tirofiban and the number of retrieval attempts relate to symptomatic intracranial hemorrhage (sICH) in patients undergoing endovascular therapy (EVT). Key Findings Participants: 866 patients were analyzed. Tirofiban Use: Patients receiving tirofiban had a higher risk of sICH (OR: 1.853). Retrieval Attempts: More than 2 retrieval attempts significantly increased…
Modifiable Prognostic Factors of High Societal Costs in Musculoskeletal Disorders Background Musculoskeletal disorders create significant challenges for society. This study focuses on understanding factors that can be changed to reduce high societal costs for individuals on sick leave due to these disorders. Methods We analyzed data from a clinical trial involving 509 participants in Norway.…
Evaluation of Treatment for Pterygium Study Overview: This study investigates the benefits of modified limbal stem cell transplantation (Modified LSC) combined with bandage contact lens (BCL) implantation in treating pterygium. Objective: To assess how effective Modified LSC and BCL are in improving outcomes after pterygium surgery. Methods: A total of 479 patients with primary pterygium…
Effect of Cognitive-Behavioral Therapy-Based Physical Play on Children’s Empathy Study Overview This study aimed to see if a sports game intervention based on cognitive-behavioral therapy could improve empathy in children with intellectual disabilities. Methodology A total of 31 children aged 7-8, diagnosed with intellectual developmental disorder, participated in the study. They were divided into two…
Efficacy and Safety of Minocycline in Retinitis Pigmentosa Study Overview Retinitis pigmentosa (RP) leads to the gradual loss of vision due to the death of photoreceptor cells. This process is worsened by the activation of microglia, which are immune cells in the eye. Currently, there is no agreed-upon treatment for RP. Minocycline is known to…
Ocrelizumab in Early-Stage Relapsing-Remitting Multiple Sclerosis Study Overview This study evaluated the effectiveness and safety of ocrelizumab as a first-line treatment for patients with early-stage relapsing-remitting multiple sclerosis (RRMS) over four years. Key Findings Patient Profile: 678 patients aged 18-55 with early-stage RRMS participated. No Evidence of Disease Activity: 66.4% of patients showed no evidence…
Comparison of Latex and Silicone Indwelling Catheters Study Overview This study examines the rate of bacterial colonization in two types of catheters—Latex and Silicone—used in males with acute urinary retention after 5 days of catheterization. Background Urinary catheterization is a common procedure, but it can lead to catheter-associated urinary tract infections (CAUTI), which are frequent…
COMPARISON OF DENTIN HYPERSENSITIVITY MANAGEMENT By Dentin Bonding Agent and Thinly Applied Glass Ionomer Cement: A Clinical Trial BACKGROUND: Dentin hypersensitivity is a widespread issue in dentistry, often referred to as the “common cold” of dental problems. This study aimed to compare the effectiveness of glass ionomer cement and dentin bonding agent in treating this…
Mediators of Change in Online Trauma Intervention Study Overview This study explores how early online interventions for trauma can help. It focused on a 3-week therapist-guided program that uses prolonged exposure therapy, comparing it to a waiting-list control group. Key Findings The research aimed to see if improvements in specific PTSD symptoms during the intervention…
A Comparative Study of Esketamine-Propofol vs Sufentanil-Propofol for Breast Surgery Study Overview This study investigates two anesthesia methods for patients undergoing breast surgery: esketamine-propofol and sufentanil-propofol. The goal is to find out which method is safer and more effective for pain relief and sedation. Study Purpose Minimally invasive rotary resection (MIRR) is vital for breast…
Clinical Trial Overview Objective: This study aimed to assess how effective and safe Buzhongyiqi pills (BZYQP) are in improving the appetite of colorectal cancer patients undergoing chemotherapy. Trial Design This was a pilot, randomized, single-blind cross-over clinical trial involving patients diagnosed with stage II-IV colorectal cancer receiving chemotherapy. Methods Participants were divided into two groups:…
The Impact of Baduanjin Exercise on Mental Health and Heart Rate Variability in College Students Study Overview This study looked at how a 16-week Baduanjin exercise program affected the mental health and heart rate variability (HRV) of college students who face challenges in sports. The goal was to see if this exercise could help improve…
Study Overview This research focused on how black tea drinks with inulin and dextrin (BTID) affect blood sugar levels in patients with type 2 diabetes (T2DM). It was a well-structured clinical trial comparing BTID to a placebo. Key Findings Significant Blood Sugar Control A total of 35 patients participated, with 32 completing the study. The…
Combined Mindfulness and Physical Activity for Better Mental Health Study Overview This study explored how combining mindfulness-based stress reduction (MBSR) and physical activity (PA) can enhance sleep quality and mental health in patients with Major Depressive Disorder (MDD). Key Findings Participants: 67 patients with MDD, averaging 35 years old, all on sertraline treatment. Groups: Patients…
Mindfulness Training for Children with ADHD Background Attention Deficit Hyperactivity Disorder (ADHD) is a common condition in school-aged children, characterized by inattention, hyperactivity, and impulsivity. Mindfulness training can help improve these symptoms and enhance emotional well-being, leading to a better quality of life. Aim The study aimed to explore how mindfulness training affects attention, impulsivity,…
Evaluation of Residual Carious Dentin Detection Methods Study Overview This study examines different methods for detecting leftover caries after tooth cavity preparation. The goal is to remove only the harmful caries while preserving healthy dentin. Methods Used The trial involved three methods: Visual-Tactile Method (Group A) Caries Detector Dye (CDD – Group B) Laser Fluorescence…
Self-Collection of Specimens for Chlamydia and Gonorrhea Testing Study Overview This study focused on whether self-collected samples could effectively diagnose Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections among men who have sex with men (MSM) in China. The goal was to make testing more accessible for those who hesitate to visit clinics. Key Findings…
Protocol Overview Study Title: Hyperbaric Oxygen Therapy (HBOT) for Treating Vaso-Occlusive Crisis (VOC) in Sickle Cell Disease (SCD) Publication: BMJ Open, November 2024 Introduction Sickle cell disease (SCD) is a common genetic disorder that affects many newborns and leads to serious complications, including vaso-occlusive crisis (VOC). VOC can cause severe pain and significantly reduce life…
iDiabetes Platform: Enhancing Diabetes Care in Scotland Introduction and Aim Diabetes is a major global health issue, leading to serious health problems and increasing deaths. One challenge is applying research findings to improve diabetes care. We propose a solution through a new digital platform called ‘intelligent Diabetes’ (iDiabetes). This platform aims to provide personalized diabetes…