Assessing Changes in Motor Function and Mobility in Individuals with Parkinson’s Disease Study Overview This study looked at how 12 sessions of patient-specific adaptive dynamic cycling (PSADC) compared to non-adaptive cycling (NA) affected motor function and mobility in people with Parkinson’s disease (PD). We used advanced sensors to measure changes accurately. Methodology Twenty-three participants with…
Targeted Biofeedback Training to Improve Gait in Stroke Patients Study Overview This study explores how biofeedback (BFB) training can help stroke patients regain their walking ability. BFB training uses specific walking targets to guide rehabilitation. Key Findings Stroke patients often have uneven walking patterns, especially during the stance phase. The study involved 60 participants: 40…
Efficacy of Customized Insoles for Diabetic Foot Pressure Study Overview This study looked at how customized insoles affect foot pressure in patients with diabetic neuropathy. It compared results from patients using the insoles to those using a placebo over three and six months. Key Findings Background: Diabetic neuropathy can be detected early in patients with…
The Application of Directional Preference for Chronic Knee Pain Overview This study focused on chronic knee pain in Brazilian Jiu-Jitsu practitioners (BJJPs). It evaluated the effectiveness of the McKenzie Method of Mechanical Diagnosis and Therapy (MDT) using Directional Preference (DP) to improve function and reduce pain. Study Details Sixty-five BJJPs with chronic knee pain were…
Immediate Effects of Soft Tissue Mobilization and Percussive Massage on Balance in Young Adults with Pes Planus Study Overview This study looked at how two treatments, IASTM (Instrument Assisted Soft Tissue Mobilization) and PMT (Percussive Massage Therapy), affect balance in young adults with flat feet (pes planus). Methodology We diagnosed pes planus using the navicular…
Effectiveness of Manual Therapy for Carpal Tunnel Syndrome Study Overview This study aimed to find out if combining cervical spine manual therapy (CMT) with traditional physical therapy (PT) leads to better outcomes for people with carpal tunnel syndrome (CTS) compared to using PT alone. Methodology Forty-eight patients diagnosed with CTS were split into two groups:…
Effectiveness of Scapula Mobilization Technique for Cervical Pain Study Overview This study investigates whether scapula mobilization can improve nerve sensitivity in patients with neck pain (cervicalgia). Cervicalgia is localized neck pain caused by nerve root compression, often linked to muscles around the scapula. Methods We recruited 60 adults with cervicalgia and a positive upper limb…
A Pilot Study on Qigong for Parkinson’s Disease Background Neuroinflammation is a key factor in the decline of neurons in people with Parkinson’s disease (PD). High levels of inflammatory markers, like IL-1β, IL-6, and TNF-α, are common in PD patients and relate to various non-motor symptoms. Qigong, a mind-body exercise, has been used to help…
Carrageenan and Insulin Resistance in Humans: A Clinical Trial Overview Study Background This study investigates the effects of carrageenan, a common food additive, on insulin resistance and inflammation in humans. While it is known to cause issues in animal studies, its impact on human health is not fully understood. Study Design A total of 20…
Effects of Canagliflozin on Patients with Type 2 Diabetes on Peritoneal Dialysis Study Overview Patients with type 2 diabetes (T2D) who are on dialysis face a higher risk of death due to heart and blood vessel issues. This study looks at how a medication called canagliflozin, which is used for T2D, affects heart health in…
A Phase II Study on Lenalidomide and Dexamethasone for Relapsed Multiple Myeloma Background Allogeneic stem cell transplant is currently the only potential cure for multiple myeloma (MM), but most patients will relapse. This study aimed to explore the effectiveness and safety of lenalidomide and dexamethasone (Len/Dex) followed by donor lymphocyte infusions (DLIs) in patients who…
Contrast-Enhanced Ultrasound vs. MRI for Liver Lesions Study Overview This study compares contrast-enhanced ultrasound (CEUS) with MRI for identifying focal nodular hyperplasia (FNH) and hepatocellular adenoma (HCA). MRI can be expensive and uncomfortable for patients, so we wanted to see if CEUS could provide similar results. Trial Details Approved by the institutional review board, this…
Effectiveness of the Community Paramedicine at Home (CP@home) Program Overview This study evaluates the CP@home program, which provides home visits by community paramedics to reduce emergency medical services (EMS) calls among frequent users in Ontario. Study Design The research was a 6-month randomized controlled trial, meaning participants were randomly assigned to either the CP@home program…
The Impact of Virtual Education on Women’s Breast Self-Examination Skills Study Overview This study explored how virtual education affects women’s ability to perform breast self-examinations (BSE), which is vital for early breast cancer detection. The goal was to see if online programs could improve knowledge, self-efficacy, and practical skills related to BSE. Methodology A total…
Efficacy and Safety of Mesenchymal Stem Cells in Treating Steroid-Refractory Acute Graft-Versus-Host Disease Background Many patients with acute graft-versus-host disease (aGVHD) do not respond well to corticosteroids. Mesenchymal stem cells (MSCs) may offer an effective second-line treatment for these patients, but more clinical studies are needed. Study Overview This study involved 78 patients with steroid-refractory…
Efficacy and Safety of Neurocognitive Adaptive Training for Depression A 12-Week Study Overview This study explored how Neurocognitive Adaptive Training for Depression (NCAT-D) works with selective serotonin reuptake inhibitors (SSRIs) to help patients with cognitive issues due to late-life depression (LLD). Study Details Conducted from May 5, 2021, to April 21, 2023, at Beijing Anding…
Randomized Controlled Trial of Cilostazol Addition for In-Stent Restenosis After Carotid Artery Stenting Background Restenosis, or narrowing of the arteries, after carotid artery stenting (CAS) can increase the risk of ischemic stroke. This study looked at whether adding cilostazol to treatment could reduce this risk. Methods In this trial, patients with carotid artery issues scheduled…
Study on Self-Management for People with Epilepsy Introduction Self-management tools can make epilepsy treatment more effective and accessible. However, we need more long-term data to prove their benefits. The Transtheoretical Model (TTM) helps tailor self-management to where individuals are in their behavioral change journey. This model aims to address specific needs, reduce information overload, minimize…
Development of a Mobile Health Support Program for Nigerian Women with Breast Cancer Background Breast cancer (BC) is a major health issue worldwide, particularly in Nigeria, where it has high rates of occurrence and death. Chemotherapy, a common treatment, can cause physical and emotional challenges that affect patients’ quality of life. There is a need…
Improving HIV Care for South African Men: Study Overview Background To control the HIV epidemic, it’s vital to increase HIV testing and treatment among people living with HIV (PLHIV). Unfortunately, men, especially in South Africa, are less likely to know their HIV status or begin treatment compared to women. Many men are also at a…