Impact of a 12-Week Dietary Intervention on Adipose Tissue Metabolic Markers in Overweight Women of Reproductive Age Study Overview The study aimed to assess the effects of a 12-week dietary intervention on metabolic markers of adipose tissue in overweight women of reproductive age. It compared the effectiveness of calorie restriction and low-starch diets, taking into…
The Effect of Curcumin on Reducing Atherogenic Risks in Obese Patients with Type 2 Diabetes: A Randomized Controlled Trial Study Overview Curcumin, derived from turmeric root, has been found to have anti-inflammatory effects, and this study aimed to assess its potential in reducing the risk of atherosclerosis in obese patients with type 2 diabetes. The…
Effect of Rosuvastatin versus Atorvastatin on New-Onset Diabetes Mellitus in Patients Treated with High-Intensity Statin Therapy for Coronary Artery Disease Key Findings: Among patients with coronary artery disease (CAD) receiving high-intensity statin therapy, the incidence of new-onset diabetes mellitus (NODM) was not significantly different between those treated with rosuvastatin and atorvastatin. However, a notable drug…
Impact of Fine Needle Aspiration Cytology Strategy for Diagnosis of Tuberculous Lymphadenitis Introduction In India, tuberculosis (TB) is a significant concern, particularly in individuals with HIV/AIDS. Extrapulmonary TB (EPTB) accounts for about 50% of TB cases, with tuberculous lymphadenitis being the most common form, representing around 35% of EPTB cases. Fine needle aspiration cytology (FNAC)…
Primary Premature Ejaculation Treatment Study Exploring Warm Acupuncture with Large-Quantity Moxibustion Objective: To investigate the clinical impact of warm acupuncture with large-quantity moxibustion on primary premature ejaculation (kidney deficiency and liver stagnation). Methods: 240 patients were randomly assigned to a warm acupuncture group, an acupuncture group, or a western medication group. The warm acupuncture group…
Practical Solutions for Postherpetic Neuralgia Treatment Combining Traditional Techniques with Modern Medicine Pricking-cupping combined with auricular thumbtack needle treatment has shown promising results for postherpetic neuralgia (PHN) of qi stagnation and blood stasis on chest and waist. This randomized controlled trial compared this approach with oral pregabalin capsule treatment. Key Findings: Patients receiving pricking-cupping combined…
Effect of Utilizing Different Data Sources on Clinical Trial Findings Key Findings: A study investigated the impact of using self-reported questionnaires, administrative data, or a combination of both on the outcomes of a long-term clinical trial. Results showed that utilizing different data sources had no significant impact on the study findings compared to when outcomes…
Empowering mind-body wellness: effect of bundling seated exercises and psychoeducational rehabilitation using the teach-back approach on fatigue and coping of women postmastectomy ABSTRACT Being diagnosed with Breast Cancer (BC) can cause significant fatigue and disrupt a patient’s life. Our study aimed to investigate the impact of combining seated exercises and psychoeducational rehabilitation using the teach-back…
Inflammatory Markers and Noncoding-RNAs Responses to HIIT and Berberine Supplementation in Prediabetic Men Study Overview This study compared the effects of two different models of high-intensity interval training (HIIT) with or without berberine supplementation on inflammatory markers and insulin resistance in middle-aged men with prediabetes and overweight or obesity. Key Findings All exercise interventions led…
Surgical Advantage of Modified Labial Salivary Gland Biopsy Using Chalazion Forceps: A Prospective Randomized Controlled Study Key Findings: Modified labial salivary gland biopsy (LSGB) using chalazion forceps showed significant advantages over traditional LSGB, including: Smaller incision Shorter operative time Less intraoperative bleeding Lower 24-hour post-surgery pain score Better incision healing at 7 days after surgery…
The Effect of Chinese Herbal Medicine on Male Factor Infertility: Study Protocol for a Randomized Controlled Trial Background The global prevalence of infertility is 9%, with male factors potentially accounting for 40% to 60% of cases. Conventional treatments can be ineffective, invasive, costly, and linked to adverse effects and high risks. Previous studies have shown…
Clinical Effect of MB-PDT Assisted Initial Therapy on Alveolar Angle Absorption of Lower Anterior Teeth Abstract Purpose: To assess the impact of MB-PDT assisted essential therapy on angle resorption of lower anterior alveolar bone in patients with periodontitis. Methods: Forty patients with periodontitis stage III-IV or C, lower anterior teeth alveolar bone angle resorption, and…
Modern Pharmacotherapy of Acute Bacterial Sinusitis: Clinical Trial Results Objective To compare the effectiveness of Cefixim Express and Suprax Solutab in treating acute bacterial sinusitis. Methods 60 adult patients with acute bacterial sinusitis were divided into two groups. Group 1 received Cefixim Express, and Group 2 received Suprax Solutab. Both groups took 400 mg dispersible…
Benefits of Budesonide/Glycopyrronium/Formoterol Fumarate Dihydrate on COPD Overview This post-hoc analysis from the KRONOS study explores the effects of triple therapy with Budesonide/Glycopyrronium/Formoterol Fumarate Dihydrate (BGF) compared to dual therapies on lung function and exacerbations in COPD patients without asthma diagnosis. The focus is on blood eosinophil count and exacerbation history. Practical Solutions For patients…
COMEDI Study: Improving Cataract Surgery Outcomes Introduction The COMEDI study explores the benefits of combining monofocal and extended depth-of-focus (EDOF) intraocular lenses (IOLs) in cataract surgery. EDOF lenses offer a wider range of vision compared to monofocal lenses, and are a promising alternative to multifocal lenses which can cause visual side effects. Methods and Analysis…
Efficacy and Safety Evaluation of 177Lu-FAP-2286 in Advanced Lung Cancer Treatment Study Overview The study aimed to assess the effectiveness and safety of peptide-targeted radionuclide therapy (PTRT) with 177Lu-FAP-2286 in patients with advanced lung cancer. Results and Findings Short-term efficacy assessment showed 44% of patients had a partial metabolic response, 33.3% had stable metabolic disease,…
Possibilities of Azilsartan Medoxomil for Preparation for Planned Percutaneous Coronary Intervention in Patients With Type 2 Diabetes Mellitus Key Findings Evaluation of the efficacy and safety of azilsartan medoxomil for preoperative preparation and improving the long-term prognosis of elective percutaneous coronary intervention (PCI) in patients with ischemic heart disease (IHD), arterial hypertension (AH), and type…
Knee Arthroscopic Surgery in Middle-Aged Patients With Meniscal Symptoms: A 10-Year Follow-up of a Prospective, Randomized Controlled Trial ABSTRACT Background: Previous evaluations of arthroscopic meniscal surgery showed little or no benefit in the short and midterm, but long-term effects were unknown. Purpose: To compare the 10-year outcomes in middle-aged patients with meniscal symptoms between those…
Study on Anticoagulant Treatment for Portal Vein Thrombosis in Cirrhosis Patients Objective To compare the safety and effectiveness of two anticoagulant treatments for portal vein thrombosis (PVT) in cirrhosis patients. Methods Cirrhotic patients with PVT received low-molecular-weight heparin calcium (LMWH-Ca) injections for 2 weeks. They were then randomly assigned to receive either warfarin or rivaroxaban…
Treatment of Temporomandibular Joint Internal Derangement using MESNA Injection Introduction The study focuses on using MESNA injection to treat temporomandibular joint (TMJ) internal derangement, targeting the inflammation that contributes to TMJ diseases. Objectives The aim was to evaluate the effectiveness of injecting MESNA directly into the TMJ for treating internal derangement. Materials and Methods A…