miR-221-3p: A Potential Biomarker for Chronic Periodontitis
Overview
Researchers investigated the role of miR-221-3p in chronic periodontitis (CP) development and management. They aimed to uncover its diagnostic potential and therapeutic implications.
Key Findings
- miR-221-3p levels were lower in CP patients compared to healthy individuals.
- miR-221-3p demonstrated high diagnostic accuracy for CP, showing potential as a biological marker.
- It was negatively correlated with periodontal indicators and inflammatory factors.
- Overexpression of miR-221-3p reduced the production of inflammatory factors in lab-induced cells.
Clinical Relevance
The expression of miR-221-3p holds promise as a diagnostic bioindicator for chronic periodontitis. This research opens up new possibilities for CP diagnosis and treatment.
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