Association between Homocysteine and Vitamin D Levels in Asymptomatic Korean Adults

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Association between Homocysteine and Vitamin D Levels in Asymptomatic Korean Adults

Summary

  • An increased homocysteine level is a risk factor for cardiovascular disease, venous thromboembolism, cerebrovascular disease, and chronic kidney disease.
  • Vitamin D deficiency is associated with coronary artery disease and metabolic disorders.
  • The study included data from 1375 adults (895 men and 480 women) with a mean age of 52.62 ± 9.94 years.
  • Homocysteine levels were positively associated with age, hypertension, diabetes, smoking habits, and levels of low-density lipoprotein cholesterol, creatinine, uric acid, and high-sensitivity C-reactive protein.
  • Vitamin D levels were negatively associated with serum levels of homocysteine after adjusting for covariates.
  • Long-term prospective studies are needed to establish a causal relationship between vitamin D status and serum levels of homocysteine in asymptomatic Korean adults.
  • An intervention trial is warranted to determine whether vitamin D administration is helpful for the primary prevention of cardiovascular disease by lowering the homocysteine level in this population.

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Full research Association between Homocysteine and Vitamin D Levels in Asymptomatic Korean Adults: https://pubmed.ncbi.nlm.nih.gov/38674846/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=1B1L42DK3a-JWCV4P_PtHHBmWjwBLFNcDXsYJkbqjQD0Ca7UQh&fc=None&ff=20240427133354&v=2.18.0.post9+e462414

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