Dr M. Trenton

“`html Study Title: Spatial profiling of ovarian carcinoma and tumor microenvironment evolution under neoadjuvant chemotherapy Purpose Investigate changes in immune tumor microenvironment (iTME) in ovarian cancer patients undergoing neoadjuvant chemotherapy (NACT) Correlate changes in immune cell subsets and coregulators with clinical outcomes Experimental Design Used multiplexed immune profiling and cell clustering analysis on paired ovarian […] ➡️➡️➡️

“`html Characterizing Technology Use and Preferences for Health Communication in South Asian Immigrants With Prediabetes or Diabetes: Cross-Sectional Descriptive Study JMIR Form Res. 2024 Apr 26;8:e52687 Background: Type 2 diabetes is a significant concern for South Asian groups. Lifestyle programs can help manage diabetes, but they need to be adapted for mobile health (mHealth). Objective: […] ➡️➡️➡️

“`html Protocol for a Prospective Noninterventional Study Importance of Early Detection of Preeclampsia in Pregnant Women Preeclampsia affects 2%-8% of pregnancies and can lead to high maternal and fetal mortality rates due to late identification. Misfolded proteins in urine samples may serve as a promising biomarker for predicting preeclampsia. Study Objectives and Methods Evaluate the […] ➡️➡️➡️

“`html Summary of Clinical Trial Results A study was conducted to evaluate the effectiveness of an educational program using technology-enhanced learning to teach neurology residents how to identify interictal epileptiform discharges (IEDs). Methods Junior neurology residents were randomly assigned to three groups: control, intervention 1, and intervention 2. The intervention involved video tutorials and rating […] ➡️➡️➡️

“`html Feasibility of Exergaming for Upper Extremity Rehabilitation in People with Multiple Sclerosis: Prospective Clinical Trial Background Exergaming has been suggested as a more motivational rehabilitation method for people with multiple sclerosis (MS). However, the lack of specific scenarios designed for people with MS is a major disadvantage. Objectives This study aims to assess the […] ➡️➡️➡️

“`html Predisposing, Precipitating, and Perpetuating Factors of Insomnia in Cancer Survivors Objective To identify the factors contributing to insomnia in cancer survivors, including those that make it more likely, those that trigger it, and those that maintain it at subthreshold, moderate, and severe levels. Sample & Setting 135 cancer survivors participating in a clinical trial […] ➡️➡️➡️

Diagnostic Performance of Fluorescein-Guided Sentinel Lymph Node Biopsy in Early Breast Cancer Practical Solutions and Value Traditional methods for evaluating axillary lymph nodes in early breast cancer are resource-intensive. Fluorescein Sodium (FS)-guided sentinel lymph node biopsy (SLNB) offers a low-cost alternative. Meta-analysis shows a high Sentinel Lymph Node Identification Rate (SLN-IR) of 93% and a […] ➡️➡️➡️

“`html Measuring critical force in sport climbers: a validation study of the 4 min all-out test on finger flexors PURPOSE Study aimed to validate critical force (CF) for finger flexors derived from the 4 min all-out test as a boundary for the highest sustainable work intensity in sport climbers. METHODS Twelve participants performed the 4 […] ➡️➡️➡️

Document Factors Affecting Physical Activity in Pediatric Cancer Survivors Published in: Eur J Pediatr. 2024 Apr 26. DOI: 10.1007/s00431-024-05584-6 Abstract Pediatric cancer survivors (PCS) with overweight and obesity are at risk for secondary chronic diseases. Despite the benefits of physical activity (PA) after treatment, PCS have low PA levels. This highlights the need for lifestyle […] ➡️➡️➡️

“`html Evaluation of Large Language Models in Breast Cancer Clinical Scenarios Practical Solutions and Value Large language models (LLMs) like GPT-3.5, GPT-4.0, and Claude2 have shown potential in breast cancer diagnosis, treatment, and care. A study compared the performances of these LLMs in clinical scenarios related to breast cancer. Clinical scenarios were categorized into assessment […] ➡️➡️➡️

“`html Study Title The Acute Effects of Ball Pressure on Anticipation Timing Following a Series of Purposeful Headers in Adult Football (Soccer) Players Objective To investigate the immediate impact of ball pressure on anticipation timing after purposeful headers in adult soccer players. Practical Solutions Use of lower-pressure and higher-pressure match balls for headers Assessment of […] ➡️➡️➡️

“`html Practical Solutions and Value of SoftVue Breast Tomographic Ultrasound (BTUS) This clinical trial article highlights the practical solutions and value of SoftVue BTUS in breast cancer screenings and theranostic treatments. Key Insights and Vision Review provides unique insights into the scientific scope and clinical vision of SoftVue BTUS inventors and pioneers. Over 20-year collaboration […] ➡️➡️➡️

“`html An Evaluation of Racial and Ethnic Representation in Research Conducted with Young Adults Diagnosed with Cancer Practical Solutions and Value Research found that young adults with cancer from diverse racial and ethnic groups are under-represented, leading to incomplete understanding of their psychosocial outcomes. Using data from the Young Adults with Cancer in Their Prime […] ➡️➡️➡️

“`html Improved Diagnosis and Treatment for Myelodysplastic Neoplasms (MDS) with Ring Sideroblasts or SF3B1 Mutations Study Overview Reviewed 395 MDS patients at our center from 2018 to 2023 Identified 39 patients with lower-risk MDS and SF3B1 mutations Supports the revised 2022 definitions of the World Health Organization (WHO) and International Consensus Classification (ICC) Key Findings […] ➡️➡️➡️

“`html Physiological Variability during Prehospital Stroke Care: Which Monitoring and Interventions Are Used? Healthcare (Basel). 2024 Apr 15;12(8):835 ABSTRACT Prehospital care for stroke is crucial for quick diagnosis and management. This review looks at how monitoring and interventions for physiological parameters in stroke patients can be improved to enhance outcomes. The review included 19 studies […] ➡️➡️➡️

“`html Effectiveness of Non-Pharmacological Interventions for Dementia among the Elderly: A Randomized Controlled Trial Summary No medicine can cure dementia, but non-pharmacological treatments can help slow down the disease and reduce symptoms. Pharmacological treatments have side effects and are expensive, making non-pharmacological interventions more urgent. This study evaluated the effectiveness of non-pharmacological interventions in dementia […] ➡️➡️➡️

The Flow-S Device: A Practical Solution for Field-Based Diagnosis of Schistosoma Infection Background: – A new device called Flow-S has been developed to simplify the diagnosis of active Schistosoma infection in the field using urine samples. – Current laboratory-based tests for this infection require complex pre-treatment steps that are not suitable for field use. Key […] ➡️➡️➡️

“`html Carbohydrate Antigen 125 (CA 125): A Novel Biomarker in Acute Heart Failure Practical Solutions and Value Heart failure is a major global health issue with high hospitalization rates and mortality. There is a need for new and reliable biomarkers for diagnosing, predicting outcomes, and guiding treatment for patients with acute heart failure. Recent research […] ➡️➡️➡️

“`html Development and Characterisation of a New Patient-Derived Xenograft Model of AR-Negative Metastatic Castration-Resistant Prostate Cancer Key Points: Prostate cancer is evolving, leading to more treatment-induced neuroendocrine and double-negative prostate cancer cases. These subtypes are resistant to standard treatments, making it challenging to find effective therapies. The CU-PC01 PDX model represents AR-negative mCRPC with specific […] ➡️➡️➡️

“`html Primary Arterial Hypertension and Cognitive Function in Young Adults Key Findings: Young adults with primary hypertension (PH) showed poorer performance in tasks of response speed and sustained attention compared to healthy controls. High office systolic blood pressure (oSBP) was independently associated with poor sustained attention. Practical Solutions and Value: Regular monitoring and management of […] ➡️➡️➡️