Dr M. Trenton

Clinical Study Overview This study focused on how effective different strengths of hydrogen peroxide (HP) are for in-office dental bleaching, and how they affect tooth sensitivity and patients’ quality of life. Study Details The trial included 54 participants who received bleaching treatments using three different concentrations of hydrogen peroxide: 18%, 25%, and 40%. The following […] ➡️➡️➡️

Background Finding patients with inherited colorectal cancer (CRC) can greatly help in managing their health. However, many people hesitate to get genetic testing for CRC, leading to low participation rates. As genetic testing becomes more common, we need better ways to help people make informed choices and increase the number of at-risk individuals who get […] ➡️➡️➡️

Background New care models that combine technology can help manage the increasing needs of older adults. However, how effective they really are is still unclear. Objective This study aimed to see how well a new care model, called SMART, could improve the quality of life for older adults living at home. Methods In this study, […] ➡️➡️➡️

Introduction More patients with metastatic colorectal cancer (mCRC) are now showing no signs of disease after treatment. However, current guidelines don’t clearly recommend ongoing treatment for these patients. Capecitabine metronomic chemotherapy is a promising option due to its effectiveness and low side effects, yet no randomized controlled trials (RCTs) have been done on this approach. […] ➡️➡️➡️

Background Postpartum depression (PPD) can affect up to 1 in 5 new parents, leading to more episodes of depression in the future. This study explored whether a one-day online workshop using cognitive behavioral therapy (CBT) could help prevent PPD. Methods This trial involved pregnant individuals at 28-38 weeks who were at high risk for PPD […] ➡️➡️➡️

Importance of Clinical Trials in Cancer Treatment Historically, less than 10% of adults with cancer participate in clinical trials, even though these trials can offer new treatment options. Study Objective This study aimed to see if informing oncologists about specific clinical trials, identified by artificial intelligence (AI), would increase participation when patients’ cancer worsened. Study […] ➡️➡️➡️

Clinical Trial Overview This clinical trial studied the effects of different in-office tooth bleaching gels on tooth sensitivity, gum irritation, and overall patient satisfaction. Study Design 160 participants were divided into two groups of 80. Each group used a different bleaching gel: Whiteness HP Maxx (acidic, unstable pH) Whiteness HP Automixx Plus (neutral, stable pH) […] ➡️➡️➡️

Understanding the Organic Halo Effect This study looks at how organic food labels affect people’s views on calorie content and how often they should eat different types of food. It has been found that organic labels may make foods seem healthier, but the impact varies based on whether the food is high or low in […] ➡️➡️➡️

AIM This study looks at how adding stretching of the hamstring muscles affects pain and mouth opening in people with jaw pain (TMD) when combined with standard treatments like ultrasound therapy. MATERIALS AND METHODS We studied 56 participants aged 18 to 35 years with TMD, randomly dividing them into two groups. The first group (Experimental […] ➡️➡️➡️

Study Overview This study looked at how different types of information affect pain levels in people experiencing low back pain (LBP) after a specific exercise. Study Details Fifty healthy individuals who had never trained with weights participated in the study. They performed a back exercise that was expected to cause some muscle soreness. One group […] ➡️➡️➡️

Introduction As people age, they face more health issues related to heart and metabolism, which can increase healthcare costs. To help older adults maintain their physical health, the RESTART trial is testing a lifestyle program aimed at improving fitness and strength in those at risk of heart disease. Study Overview The RESTART trial is a […] ➡️➡️➡️

Background Chronic cluster headache is a rare but very painful condition that causes severe headaches without long breaks between attacks. It can be hard to treat because there are few options available. Eptinezumab is a new treatment that targets a specific protein involved in these headaches. The CHRONICLE trial studied how safe and effective eptinezumab […] ➡️➡️➡️

Study Overview This study investigated two non-invasive treatments for pain caused by calcaneal spurs: extracorporeal shock wave therapy (ESWT) and high-intensity laser therapy (HILT). The goal was to see which treatment was more effective in reducing pain and improving function. How the Study Was Conducted Patients with calcaneal spurs were randomly divided into two groups. […] ➡️➡️➡️

Background Artificial intelligence (AI) is becoming more common in healthcare, especially in decision support systems. Some AI systems provide predictions along with confidence levels (uncertainty-aware AI), while others only give predictions (black-box AI). It’s unclear how these different types of AI affect healthcare providers’ performance and response times. Study Objective This study explored how black-box […] ➡️➡️➡️

Clinical Trial Overview This clinical trial, conducted on April 17, 2025, focused on patients who have both Major Depressive Disorder (MDD) and Opioid Use Disorder (OUD). These conditions create significant challenges, requiring treatments that tackle both mental health and addiction issues. Aims of the Study The goal was to compare two treatments, ketamine and buprenorphine, […] ➡️➡️➡️

Overview of the CHANCES Trial The CHinA National CancEr Screening (CHANCES) Trial is a major study designed to improve cancer detection in China, specifically focusing on lung cancer and colorectal cancer (CRC). Effective cancer screening can lead to earlier diagnosis, better treatment, and lower death rates. Trial Objectives This trial aims to: Evaluate different screening […] ➡️➡️➡️

Introduction Artificial Intelligence (AI) can make learning how to perform cardiac ultrasounds easier. It provides real-time guidance on how to handle the ultrasound probe, helping users get better images for diagnosis. This study examines how AI tools can help new users learn cardiac ultrasound more effectively. Study Overview This study involved a controlled trial with […] ➡️➡️➡️

“`html Introduction Diagnosing inherited bleeding disorders can be a long and costly process. Many patients end up without a clear diagnosis, often feeling frustrated and emotionally drained. Recent advancements in genetic testing offer a promising solution to improve patient care by potentially speeding up the diagnosis process. Study Overview This study will compare two approaches […] ➡️➡️➡️

Background Breast cancer is a major health issue in Pakistan, with many women diagnosed at advanced stages. Regular screening is not common among Pakistani women, despite the increasing number of cases. There is a lack of research focused on improving breast self-examination practices in this context. Study Purpose This study aims to create and test […] ➡️➡️➡️

Background Less than 25% of people with borderline personality disorder (BPD) get the recommended therapy. Digital tools can help close this gap. This study tested a digital therapy called priovi for BPD. Methods We ran a study in Germany with patients diagnosed with moderate to severe BPD. Participants were at least 18 years old, had […] ➡️➡️➡️